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Laboratorios Made SA
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Laboratorios Made SA
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Priority to ES476088ApriorityCriticalpatent/ES476088A1/es
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Low-Molecular Organic Synthesis Reactions Using Catalysts
(AREA)
Abstract
Un procedimiento par la obtención de 1,3,3-trimetril-2-(3,4,5-trimetoxifenil)-4-metilenpiperidina de fómula (I) y sus sales de adición con ácidos farmacologicamente aceptables, por ejemplo el hidrocloruro, caracterizado porque en unq etapa de síntesis se hace reaccionar la 1-cloro-4-metil-3-pentanona con bencilmetilamina, con lo que se obtiene la 1-bencilmetilamino-4-metil-3-pentanona de fórmula (II), que se transforma en el hidrocloruro y a continuación se hidrogena catalíticamente utilizando paladio sobre carbón como catalizador para dar el hodrocloruro de la 4-metil-1-metilamino-3-pentanona de fórmula (III)
ES476088A1978-12-181978-12-18Un procedimiento para la obtencion de 1,3,3-trimetil-2-(3,4,5-trimetoxifenil)-4-metilenpiperidina.
ExpiredES476088A1
(es)