ES473547A1 - Un metodo para la preparacion de compuestos derivados de 2- oxazolidona. - Google Patents

Un metodo para la preparacion de compuestos derivados de 2- oxazolidona.

Info

Publication number
ES473547A1
ES473547A1 ES78473547A ES473547A ES473547A1 ES 473547 A1 ES473547 A1 ES 473547A1 ES 78473547 A ES78473547 A ES 78473547A ES 473547 A ES473547 A ES 473547A ES 473547 A1 ES473547 A1 ES 473547A1
Authority
ES
Spain
Prior art keywords
methyl
oxazolydone
derivatives
preparing
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES78473547A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Menarini SAS
Original Assignee
Menarini SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini SAS filed Critical Menarini SAS
Publication of ES473547A1 publication Critical patent/ES473547A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Un método para la preparación de compuestos derivados de 2- oxazolidona, de la fórmula general (I) **(Fórmula)** en donde R se elige del grupo constituido por grupos de isopropilo, n- octilo o isobutilo; R1 se elige del grupo constituido por 1-naftiloximetilo, 2- alilfenoximetilo, 4-acetaminofenoximetilo, 4- isopropiltiofenilo, 4-noitrofenilo, {2- [(tetrahidrofurfuril)oxi-]-fenoxi} metilo y [4-(2- metoxietil)fenoxi]metilo; y R2 se elige del grupo constituido por un átomo de hidrogeno y un grupo de metilo.
ES78473547A 1977-09-22 1978-09-21 Un metodo para la preparacion de compuestos derivados de 2- oxazolidona. Expired ES473547A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT779578A IT1109002B (it) 1977-09-22 1977-09-22 Derivati del 2 oxazolidone e loro metodi di preparazione

Publications (1)

Publication Number Publication Date
ES473547A1 true ES473547A1 (es) 1979-04-16

Family

ID=11132420

Family Applications (1)

Application Number Title Priority Date Filing Date
ES78473547A Expired ES473547A1 (es) 1977-09-22 1978-09-21 Un metodo para la preparacion de compuestos derivados de 2- oxazolidona.

Country Status (20)

Country Link
US (1) US4188323A (es)
JP (1) JPS5459271A (es)
AR (1) AR218933A1 (es)
AT (1) AT362368B (es)
AU (1) AU519531B2 (es)
BE (1) BE870675A (es)
CA (1) CA1118779A (es)
DD (1) DD138978A5 (es)
DE (1) DE2839907A1 (es)
DK (1) DK416278A (es)
ES (1) ES473547A1 (es)
FR (1) FR2404001A1 (es)
GB (1) GB2005261B (es)
HU (1) HU177872B (es)
IT (1) IT1109002B (es)
NL (1) NL7809647A (es)
SE (1) SE7809935L (es)
SU (1) SU947160A1 (es)
YU (1) YU225278A (es)
ZA (1) ZA785249B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4754047A (en) * 1979-08-16 1988-06-28 American Cyanamid Company Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and/or improving the efficiency of feed utilization thereby
US4522822A (en) * 1980-12-22 1985-06-11 American Cyanamid Company Phenylethane derivatives and acid addition salts thereof for increasing lean meat deposition and/or improving lean meat to fat ratio in warm blooded animals
US4501751A (en) * 1980-12-22 1985-02-26 American Cyanamid Company Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby
US4670450A (en) * 1985-11-13 1987-06-02 Merrell Dow Pharmaceuticals Inc. Cardiotonic thiazolones
US4728661A (en) * 1985-11-13 1988-03-01 Merrell Dow Pharmaceuticals Inc. Cardiotonic phenyl oxazolones
US4698353A (en) * 1985-11-13 1987-10-06 Merrell Dow Pharmaceuticals Inc. Cardiotonic heterocyclic oxazolones
IL98392A (en) * 1990-06-07 1996-01-19 Wellcome Found History of indole, their preparation and the pharmaceutical preparations containing them

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1284520A (fr) * 1958-11-03 1962-02-16 American Cyanamid Co Procédé de préparation de nouveaux composés de 2-oxazolidinones
US3062826A (en) * 1959-06-19 1962-11-06 Robins Co Inc A H 3, 4-disubstituted phenoxymethyl oxazolidones
US3062828A (en) * 1962-02-27 1962-11-06 Robins Co Inc A H 5-(alkoxyphenoxymethyl)-2-oxazolidones
US3637852A (en) * 1963-08-26 1972-01-25 Boehringer Sohn Ingelheim 1-phenoxy-2-hydroxy-3-isopropylamino-propanes and salts thereof
US3459782A (en) * 1963-08-26 1969-08-05 Boehringer Sohn Ingelheim 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes
US3331850A (en) * 1964-05-13 1967-07-18 Upjohn Co 5-(aryloxymethyl)-2-oxazolidinethiones
CH484172A (de) * 1965-07-09 1970-01-15 Ciba Geigy Verfahren zur Herstellung eines neuen Oxazolidinons
US3541130A (en) * 1967-02-06 1970-11-17 Boehringer Sohn Ingelheim 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes
GB1180089A (en) * 1967-10-20 1970-02-04 Delalande Sa Acetylenic Derivatives of 2-Oxazolidinones and processes of preparation
SE354851B (es) * 1970-02-18 1973-03-26 Haessle Ab
FR2338268A1 (fr) * 1976-01-16 1977-08-12 Nativelle Spa Nouveaux derives d'oxazolidinone, preparation et application a la synthese d'aryloxypropanolamines

Also Published As

Publication number Publication date
AU4005978A (en) 1980-03-27
AR218933A1 (es) 1980-07-15
FR2404001A1 (fr) 1979-04-20
ZA785249B (en) 1979-09-26
YU225278A (en) 1983-01-21
AT362368B (de) 1981-05-11
JPS5459271A (en) 1979-05-12
AU519531B2 (en) 1981-12-10
FR2404001B1 (es) 1980-10-31
DD138978A5 (de) 1979-12-05
BE870675A (fr) 1979-01-15
HU177872B (en) 1982-01-28
DE2839907A1 (de) 1979-04-05
NL7809647A (nl) 1979-03-26
IT1109002B (it) 1985-12-16
SU947160A1 (ru) 1982-07-30
US4188323A (en) 1980-02-12
CA1118779A (en) 1982-02-23
DK416278A (da) 1979-03-23
GB2005261B (en) 1982-03-17
GB2005261A (en) 1979-04-19
ATA674278A (de) 1980-10-15
SE7809935L (sv) 1979-03-23

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19991102