ES473096A2 - Procedure for the preparation of 15-steroids. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of 15-steroids. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES473096A2 ES473096A2 ES473096A ES473096A ES473096A2 ES 473096 A2 ES473096 A2 ES 473096A2 ES 473096 A ES473096 A ES 473096A ES 473096 A ES473096 A ES 473096A ES 473096 A2 ES473096 A2 ES 473096A2
- Authority
- ES
- Spain
- Prior art keywords
- acids
- steroids
- translation
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 3
- 150000007513 acids Chemical class 0.000 abstract 3
- -1 chloroethynyl Chemical group 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- 125000002534 ethynyl group Chemical group [H]C#C* 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 125000002568 propynyl group Chemical group [*]C#CC([H])([H])[H] 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 150000003460 sulfonic acids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
- C07J33/007—Cyclic thioketals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0096—Alkynyl derivatives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Abstract
Procedure for the preparation of -steroids of the general formula I ** (Formula) ** wherein R1 signifies a hydrogen atom, a trialkohilsilyl group or an acyl group; and R2 signifies an ethynyl, chloroethynyl or propynyl group. Suitable acyl radicals R1 are those of physiologically compatible acids. Preferred acids are organic carboxylic and sulfonic acids with 1 to 16, especially 1 to 11, carbon atoms, which belong to the aliphatic, cycloaliphatic, aromatic, aromatic-aliphatic or heterocyclic series. These acids can also be saturated or unsaturated, monobasic or polybasic and/or can be substituted in the usual way. As examples of the substituents there will be mentioned alcohol, hydroxy, alkoxy, oxo or amino groups, or halogen atoms. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2749105A DE2749105C2 (en) | 1977-10-31 | 1977-10-31 | Process for the preparation of Δ → 1 → → 5 → -17α-chloroethinyl and propynyl steroids of the estran series |
| DE2749104A DE2749104C2 (en) | 1977-10-31 | 1977-10-31 | Process for the preparation of?? 15? -Steroids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES473096A2 true ES473096A2 (en) | 1979-07-01 |
Family
ID=25773014
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES473096A Expired ES473096A2 (en) | 1977-10-31 | 1978-09-05 | Procedure for the preparation of 15-steroids. (Machine-translation by Google Translate, not legally binding) |
Country Status (9)
| Country | Link |
|---|---|
| AT (1) | AT365608B (en) |
| CA (1) | CA1122591A (en) |
| CH (1) | CH639106A5 (en) |
| DD (1) | DD139583A6 (en) |
| DK (1) | DK147005C (en) |
| ES (1) | ES473096A2 (en) |
| HU (1) | HU178117B (en) |
| IT (1) | IT1159936B (en) |
| NL (1) | NL7808509A (en) |
-
1978
- 1978-08-16 NL NL7808509A patent/NL7808509A/en not_active Application Discontinuation
- 1978-09-05 ES ES473096A patent/ES473096A2/en not_active Expired
- 1978-10-17 IT IT28810/78A patent/IT1159936B/en active
- 1978-10-25 DD DD78208663A patent/DD139583A6/en unknown
- 1978-10-30 CA CA314,900A patent/CA1122591A/en not_active Expired
- 1978-10-30 AT AT0774478A patent/AT365608B/en not_active IP Right Cessation
- 1978-10-30 HU HU78SCHE659A patent/HU178117B/en unknown
- 1978-10-31 CH CH1121878A patent/CH639106A5/en not_active IP Right Cessation
- 1978-10-31 DK DK485378A patent/DK147005C/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATA774478A (en) | 1981-06-15 |
| HU178117B (en) | 1982-03-28 |
| AT365608B (en) | 1982-02-10 |
| DK485378A (en) | 1979-05-01 |
| DK147005C (en) | 1984-08-27 |
| CA1122591A (en) | 1982-04-27 |
| DD139583A6 (en) | 1980-01-09 |
| CH639106A5 (en) | 1983-10-31 |
| DK147005B (en) | 1984-03-12 |
| NL7808509A (en) | 1979-05-02 |
| IT1159936B (en) | 1987-03-04 |
| IT7828810A0 (en) | 1978-10-17 |
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