ES472735A1 - Lumpy cellular particle like glucoseisomerase enzyme activated by iron - Google Patents

Lumpy cellular particle like glucoseisomerase enzyme activated by iron

Info

Publication number
ES472735A1
ES472735A1 ES472735A ES472735A ES472735A1 ES 472735 A1 ES472735 A1 ES 472735A1 ES 472735 A ES472735 A ES 472735A ES 472735 A ES472735 A ES 472735A ES 472735 A1 ES472735 A1 ES 472735A1
Authority
ES
Spain
Prior art keywords
glucoseisomerase
lumpy
iron
enzyme
mass
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES472735A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Industri AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB35368/77A external-priority patent/GB1596662A/en
Priority claimed from US05/827,030 external-priority patent/US4152211A/en
Application filed by Novo Industri AS filed Critical Novo Industri AS
Publication of ES472735A1 publication Critical patent/ES472735A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/24—Preparation of compounds containing saccharide radicals produced by the action of an isomerase, e.g. fructose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A cellular mass of glucose isomerase (which can conform to BP 1516704 or USP 3980521) is activated by the incor poration of at least 0.05 wt. % (on the dry base) of Fe in the form of a water-sol., non-toxic, pref. solid. Fe salt after incorporation of the Fe, the glucose isomerase is converted into particle form and dried. At least 0.5 wt. % MgO, w.r.t. the dry wt. of the cellular mass, and 2 wt. % of solid glucose are pref. mixed with the Fe before addn. to the cellular mass. The mass is then extruded into granules. The prod. is used to isomerise glucuse. The method avoids the use of (toxic Co), at the same time allowing the Fe to be introduced with the enzyme, and causing it to remain firmly bound throughout the use of the enzyme.
ES472735A 1977-08-23 1978-08-22 Lumpy cellular particle like glucoseisomerase enzyme activated by iron Expired ES472735A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB35368/77A GB1596662A (en) 1966-09-15 1977-08-23 Glucose isomerase compositions comprising iron salts
US05/827,030 US4152211A (en) 1977-08-23 1977-08-23 Iron containing cell mass glucose isomerase preparation

Publications (1)

Publication Number Publication Date
ES472735A1 true ES472735A1 (en) 1979-02-16

Family

ID=26262696

Family Applications (1)

Application Number Title Priority Date Filing Date
ES472735A Expired ES472735A1 (en) 1977-08-23 1978-08-22 Lumpy cellular particle like glucoseisomerase enzyme activated by iron

Country Status (11)

Country Link
JP (1) JPS5856639B2 (en)
AT (1) AT364879B (en)
AU (1) AU515471B2 (en)
CA (1) CA1100065A (en)
DE (1) DE2833644C2 (en)
DK (1) DK147236C (en)
ES (1) ES472735A1 (en)
FR (1) FR2401170A1 (en)
IT (1) IT1174334B (en)
NL (1) NL187584C (en)
SE (1) SE465369B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6049479B2 (en) * 1981-03-19 1985-11-01 東レ株式会社 Glucose isomerase deactivation prevention material and glucose isomerization reaction method
JPS60168644U (en) * 1984-04-18 1985-11-08 株式会社日立製作所 Lighting circuits for car radios, etc.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3779869A (en) * 1971-05-13 1973-12-18 Miles Lab Enzyme stabilization
JPS5439472B2 (en) * 1974-06-26 1979-11-28
US3980521A (en) * 1974-08-28 1976-09-14 Novo Industri A/S Immobilization of glucose isomerase
US3935069A (en) * 1974-12-23 1976-01-27 R. J. Reynolds Tobacco Company Enzymatic process using immobilized microbial cells

Also Published As

Publication number Publication date
FR2401170B1 (en) 1983-08-26
NL187584C (en) 1991-11-18
IT7850815A0 (en) 1978-08-22
AU515471B2 (en) 1981-04-02
CA1100065A (en) 1981-04-28
DK147236B (en) 1984-05-21
AT364879B (en) 1981-11-25
DE2833644A1 (en) 1979-03-01
DK368278A (en) 1979-02-24
SE7808865L (en) 1979-02-24
DE2833644C2 (en) 1985-07-11
FR2401170A1 (en) 1979-03-23
SE465369B (en) 1991-09-02
AU3833878A (en) 1980-01-31
ATA611178A (en) 1981-04-15
IT1174334B (en) 1987-07-01
DK147236C (en) 1985-01-14
JPS5444092A (en) 1979-04-07
NL7808495A (en) 1979-02-27
NL187584B (en) 1991-06-17
JPS5856639B2 (en) 1983-12-15

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990201