ES472158A1 - Procedure for the preparation of 3- (2-hydroxy-3-alkylaminopropoxy) benzotiofens and of any of its salts. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of 3- (2-hydroxy-3-alkylaminopropoxy) benzotiofens and of any of its salts. (Machine-translation by Google Translate, not legally binding)

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Publication number
ES472158A1
ES472158A1 ES472158A ES472158A ES472158A1 ES 472158 A1 ES472158 A1 ES 472158A1 ES 472158 A ES472158 A ES 472158A ES 472158 A ES472158 A ES 472158A ES 472158 A1 ES472158 A1 ES 472158A1
Authority
ES
Spain
Prior art keywords
alkylaminopropoxy
translation
hydroxy
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES472158A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consejo Superior de Investigaciones Cientificas CSIC
Original Assignee
Consejo Superior de Investigaciones Cientificas CSIC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consejo Superior de Investigaciones Cientificas CSIC filed Critical Consejo Superior de Investigaciones Cientificas CSIC
Priority to ES472158A priority Critical patent/ES472158A1/en
Publication of ES472158A1 publication Critical patent/ES472158A1/en
Expired legal-status Critical Current

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Abstract

Procedure for the preparation of 3- (2-hydroxy-3-alkylaminopropoxy) benzotiofenes and of any of its general formula salts: ** formula ** in which x represents h, one or several substituents in any position of the nucleus and any radical rent, aralquilo or ariloxialquilo. It is part of a general formula compound: ** formula ** which is treated with epiclorhydridin in the presence of potassic terc-butylate using dimetyl sulfoxide as a solvent. The compound resulting from isopropylamine treatment and rearing with naoh solution followed by acidification with diluted hcl leads to the desired compound. The compound obtained presents properties as a b-adrenergic blocker. (Machine-translation by Google Translate, not legally binding)
ES472158A 1978-07-28 1978-07-28 Procedure for the preparation of 3- (2-hydroxy-3-alkylaminopropoxy) benzotiofens and of any of its salts. (Machine-translation by Google Translate, not legally binding) Expired ES472158A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES472158A ES472158A1 (en) 1978-07-28 1978-07-28 Procedure for the preparation of 3- (2-hydroxy-3-alkylaminopropoxy) benzotiofens and of any of its salts. (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES472158A ES472158A1 (en) 1978-07-28 1978-07-28 Procedure for the preparation of 3- (2-hydroxy-3-alkylaminopropoxy) benzotiofens and of any of its salts. (Machine-translation by Google Translate, not legally binding)

Publications (1)

Publication Number Publication Date
ES472158A1 true ES472158A1 (en) 1979-03-16

Family

ID=8476571

Family Applications (1)

Application Number Title Priority Date Filing Date
ES472158A Expired ES472158A1 (en) 1978-07-28 1978-07-28 Procedure for the preparation of 3- (2-hydroxy-3-alkylaminopropoxy) benzotiofens and of any of its salts. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES472158A1 (en)

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990201