ES466363A1 - Procedimiento para la obtencion de acido n-9,10-dihidro - lisergil-m-amino-benzoico - Google Patents
Procedimiento para la obtencion de acido n-9,10-dihidro - lisergil-m-amino-benzoicoInfo
- Publication number
- ES466363A1 ES466363A1 ES78466363A ES466363A ES466363A1 ES 466363 A1 ES466363 A1 ES 466363A1 ES 78466363 A ES78466363 A ES 78466363A ES 466363 A ES466363 A ES 466363A ES 466363 A1 ES466363 A1 ES 466363A1
- Authority
- ES
- Spain
- Prior art keywords
- acid
- amino
- obtaining
- formula
- lisergil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 2
- DTQVDTLACAAQTR-UHFFFAOYSA-N Trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-N 0.000 abstract 2
- CTSLXHKWHWQRSH-UHFFFAOYSA-N oxalyl chloride Chemical compound ClC(=O)C(Cl)=O CTSLXHKWHWQRSH-UHFFFAOYSA-N 0.000 abstract 2
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- ZAGRKAFMISFKIO-UHFFFAOYSA-N Isolysergic acid Natural products C1=CC(C2=CC(CN(C2C2)C)C(O)=O)=C3C2=CNC3=C1 ZAGRKAFMISFKIO-UHFFFAOYSA-N 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 150000001540 azides Chemical class 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- ZAGRKAFMISFKIO-QMTHXVAHSA-N lysergic acid Chemical compound C1=CC(C2=C[C@H](CN([C@@H]2C2)C)C(O)=O)=C3C2=CNC3=C1 ZAGRKAFMISFKIO-QMTHXVAHSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH107077 | 1977-01-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES466363A1 true ES466363A1 (es) | 1979-01-16 |
Family
ID=4201739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES78466363A Expired ES466363A1 (es) | 1977-01-28 | 1978-01-26 | Procedimiento para la obtencion de acido n-9,10-dihidro - lisergil-m-amino-benzoico |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US4180581A (enExample) |
| JP (1) | JPS5395999A (enExample) |
| AT (1) | ATA59078A (enExample) |
| AU (1) | AU3281078A (enExample) |
| BE (1) | BE863366A (enExample) |
| CA (1) | CA1105008A (enExample) |
| DE (1) | DE2802023A1 (enExample) |
| DK (1) | DK28278A (enExample) |
| ES (1) | ES466363A1 (enExample) |
| FI (1) | FI780168A7 (enExample) |
| FR (1) | FR2378781A1 (enExample) |
| GB (1) | GB1595606A (enExample) |
| IE (1) | IE46385B1 (enExample) |
| IL (1) | IL53901A (enExample) |
| IT (1) | IT7847795A0 (enExample) |
| NL (1) | NL7800817A (enExample) |
| NZ (1) | NZ186329A (enExample) |
| PH (1) | PH14096A (enExample) |
| PT (1) | PT67586B (enExample) |
| SE (1) | SE7800633L (enExample) |
| ZA (1) | ZA78521B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4526892A (en) * | 1981-03-03 | 1985-07-02 | Farmitalia Carlo Erba, S.P.A. | Dimethylaminoalkyl-3-(ergoline-8'βcarbonyl)-ureas |
| GB2173189B (en) * | 1985-02-21 | 1988-04-27 | Maruko Pharmaceutical Co | Ergoline derivatives and salts thereof and pharmaceutical compositions thereof |
| GB8515528D0 (en) * | 1985-06-19 | 1985-07-24 | Erba Farmitalia | Ergoline derivatives |
| DE3931819A1 (de) * | 1989-09-20 | 1991-03-28 | Schering Ag | 13-brom und 13, 14-dibrom-ergoline, ihre herstellung und verwendung in arzneimitteln |
| US5441961A (en) * | 1992-08-27 | 1995-08-15 | Eli Lilly And Company | Substituted cyclo or bicycloalkylamides of (8β)-6-(substituted) ergolines |
| ATE204278T1 (de) * | 1992-12-24 | 2001-09-15 | Pharmacia & Upjohn Spa | Serotoninergische ergolin derivate |
| AUPO395396A0 (en) * | 1996-12-02 | 1997-01-02 | Fujisawa Pharmaceutical Co., Ltd. | Benzamide derivatives |
| EP4126857A1 (en) | 2021-01-15 | 2023-02-08 | Beckley Psytech Limited | Ergoline analogues |
| US12264131B2 (en) | 2022-08-19 | 2025-04-01 | Beckley Psytech Limited | Pharmaceutically acceptable salts and compositions thereof |
| US12246005B2 (en) | 2023-06-13 | 2025-03-11 | Beckley Psytech Limited | 5-methoxy-n,n-dimethyltryptamine (5-MeO-DMT) formulations |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3228942A (en) * | 1966-01-11 | Methyl and i,g-dimeti-iyl ergoline i compounds | ||
| GB1112909A (en) * | 1964-09-15 | 1968-05-08 | Sandoz Ltd | Ergoline derivatives |
| IL41409A (en) * | 1972-02-04 | 1977-04-29 | Richter Gedeon Vegyeszet | Lysergic acid amides and process for their preparation |
| CA990287A (en) * | 1972-09-26 | 1976-06-01 | Sandoz Patents Limited | 13-bromo-lysergic acid compounds |
| US3904633A (en) * | 1973-02-05 | 1975-09-09 | Richter Gedeon Vegyeszet | Lysergic amides |
| HU172649B (hu) * | 1975-04-24 | 1978-11-28 | Gyogyszerkutato Intezet | Sposob poluchenija novykh biologicheski aktivnykh lizergamidov |
-
1978
- 1978-01-18 DE DE19782802023 patent/DE2802023A1/de not_active Withdrawn
- 1978-01-19 DK DK28278A patent/DK28278A/da not_active Application Discontinuation
- 1978-01-19 FI FI780168A patent/FI780168A7/fi not_active Application Discontinuation
- 1978-01-19 SE SE7800633A patent/SE7800633L/xx unknown
- 1978-01-23 GB GB2605/78A patent/GB1595606A/en not_active Expired
- 1978-01-24 NL NL7800817A patent/NL7800817A/xx not_active Application Discontinuation
- 1978-01-26 US US05/872,639 patent/US4180581A/en not_active Expired - Lifetime
- 1978-01-26 CA CA295,744A patent/CA1105008A/en not_active Expired
- 1978-01-26 ES ES78466363A patent/ES466363A1/es not_active Expired
- 1978-01-26 IT IT7847795A patent/IT7847795A0/it unknown
- 1978-01-26 BE BE184673A patent/BE863366A/xx unknown
- 1978-01-26 IE IE182/78A patent/IE46385B1/en unknown
- 1978-01-26 NZ NZ186329A patent/NZ186329A/xx unknown
- 1978-01-26 PT PT67586A patent/PT67586B/pt unknown
- 1978-01-26 IL IL53901A patent/IL53901A/xx unknown
- 1978-01-27 AT AT0059078A patent/ATA59078A/de not_active Application Discontinuation
- 1978-01-27 JP JP746678A patent/JPS5395999A/ja active Pending
- 1978-01-27 PH PH20718A patent/PH14096A/en unknown
- 1978-01-27 AU AU32810/78A patent/AU3281078A/en active Pending
- 1978-01-27 ZA ZA00780521A patent/ZA78521B/xx unknown
- 1978-01-27 FR FR7802311A patent/FR2378781A1/fr active Granted
-
1979
- 1979-06-04 US US06/044,916 patent/US4248871A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| IT7847795A0 (it) | 1978-01-26 |
| US4180581A (en) | 1979-12-25 |
| NZ186329A (en) | 1980-11-14 |
| IL53901A0 (en) | 1978-04-30 |
| ZA78521B (en) | 1979-09-26 |
| BE863366A (fr) | 1978-07-26 |
| GB1595606A (en) | 1981-08-12 |
| PH14096A (en) | 1981-02-10 |
| JPS5395999A (en) | 1978-08-22 |
| PT67586A (en) | 1978-02-01 |
| FR2378781A1 (fr) | 1978-08-25 |
| AU3281078A (en) | 1979-08-02 |
| IL53901A (en) | 1981-01-30 |
| FR2378781B1 (enExample) | 1980-08-29 |
| IE780182L (en) | 1978-07-28 |
| DK28278A (da) | 1978-07-29 |
| US4248871A (en) | 1981-02-03 |
| DE2802023A1 (de) | 1978-08-03 |
| SE7800633L (sv) | 1978-07-29 |
| CA1105008A (en) | 1981-07-14 |
| IE46385B1 (en) | 1983-05-18 |
| ATA59078A (de) | 1981-06-15 |
| PT67586B (en) | 1981-02-02 |
| NL7800817A (nl) | 1978-08-01 |
| FI780168A7 (fi) | 1978-07-29 |
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