ES466004A2 - New analogue of prostaglandin and its preparation - Google Patents
New analogue of prostaglandin and its preparationInfo
- Publication number
- ES466004A2 ES466004A2 ES466004A ES466004A ES466004A2 ES 466004 A2 ES466004 A2 ES 466004A2 ES 466004 A ES466004 A ES 466004A ES 466004 A ES466004 A ES 466004A ES 466004 A2 ES466004 A2 ES 466004A2
- Authority
- ES
- Spain
- Prior art keywords
- compound
- preparation
- physiologically compatible
- prostaglandin
- main patent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003180 prostaglandins Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
Improvements introduced in the object of main patent no. 434,590, filed on February 10, 1975 for: "Procedure for the preparation of new analog compounds of prostanoic acids", characterized in that a compound of formula I is prepared, in which R1 and R2 together signify oxygen, according to process steps a) to p) of claim 1 of main patent no. 434,590, the compound obtained is reacted with an acylating agent, and, if necessary, the compound obtained is reduced to form a compound of the formula XXIII, in which one of the radicals R1 and R2 signifies a hydroxyl group and the other signifies hydrogen and, optionally, a free acid of the formula XXIII is transformed, according to a usual procedure, into a physiologically compatible or in a physiologically compatible ester. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19772702366 DE2702366A1 (en) | 1977-01-21 | 1977-01-21 | NEW PROSTAGLANDIN ANALOGS AND METHOD FOR THEIR PRODUCTION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES466004A2 true ES466004A2 (en) | 1978-10-01 |
Family
ID=5999192
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES466004A Expired ES466004A2 (en) | 1977-01-21 | 1978-01-16 | New analogue of prostaglandin and its preparation |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS5392740A (en) |
| BE (1) | BE863205R (en) |
| DE (1) | DE2702366A1 (en) |
| DK (1) | DK29478A (en) |
| ES (1) | ES466004A2 (en) |
| FR (1) | FR2378009A2 (en) |
| LU (1) | LU78909A1 (en) |
| NL (1) | NL7714523A (en) |
| SE (1) | SE7800688L (en) |
| ZA (1) | ZA78366B (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4045577A (en) * | 1971-06-17 | 1977-08-30 | Alza Corporation | Valuable medicinial prostaglandin compounds prepared from material isolated from the sea |
| ZA764727B (en) * | 1975-09-02 | 1977-07-27 | Upjohn Co | Prostanoic acid derivatives |
-
1977
- 1977-01-21 DE DE19772702366 patent/DE2702366A1/en active Pending
- 1977-12-29 NL NL7714523A patent/NL7714523A/en not_active Application Discontinuation
-
1978
- 1978-01-16 ES ES466004A patent/ES466004A2/en not_active Expired
- 1978-01-19 SE SE7800688A patent/SE7800688L/en unknown
- 1978-01-19 LU LU78909A patent/LU78909A1/en unknown
- 1978-01-20 ZA ZA00780366A patent/ZA78366B/en unknown
- 1978-01-20 DK DK29478A patent/DK29478A/en unknown
- 1978-01-20 JP JP573078A patent/JPS5392740A/en active Pending
- 1978-01-23 BE BE184545A patent/BE863205R/en active
- 1978-01-23 FR FR7801790A patent/FR2378009A2/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5392740A (en) | 1978-08-15 |
| NL7714523A (en) | 1978-07-25 |
| BE863205R (en) | 1978-07-24 |
| DK29478A (en) | 1978-07-22 |
| SE7800688L (en) | 1978-07-22 |
| ZA78366B (en) | 1979-01-31 |
| LU78909A1 (en) | 1978-09-28 |
| FR2378009A2 (en) | 1978-08-18 |
| DE2702366A1 (en) | 1978-08-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD2A | Announcement of lapse in spain |
Effective date: 20170706 |