ES465872A1 - 1-phenoxy-3-t-butylaminopropan-2-ols - Google Patents

1-phenoxy-3-t-butylaminopropan-2-ols

Info

Publication number
ES465872A1
ES465872A1 ES465872A ES465872A ES465872A1 ES 465872 A1 ES465872 A1 ES 465872A1 ES 465872 A ES465872 A ES 465872A ES 465872 A ES465872 A ES 465872A ES 465872 A1 ES465872 A1 ES 465872A1
Authority
ES
Spain
Prior art keywords
formula
compound
platelet aggregation
relates
butylaminopropan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES465872A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr L Zambeletti SpA
Original Assignee
Dr L Zambeletti SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr L Zambeletti SpA filed Critical Dr L Zambeletti SpA
Publication of ES465872A1 publication Critical patent/ES465872A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

This invention relates to 1- (2-nitro-methhenoxy) -3-t-butylamino-propan-2-ol of formula (I) ** (Formula) ** Where the CH3 moiety can be attached to the 3 05 positions of the benzene ring, and its physiologically acceptable salts. The invention also relates to a method for the preparation of compound (I) and to pharmaceutical compositions with platelet aggregation inhibitory activity, containing as an active principle the compound of formula (I). It has now surprisingly been found that the compounds of formula (I) can inhibit platelet aggregation, and consequently thrombus formation, in such a way as to allow the compound to be used in the prevention and therapy of thrombosis. (Machine-translation by Google Translate, not legally binding)
ES465872A 1977-01-12 1978-01-10 1-phenoxy-3-t-butylaminopropan-2-ols Expired ES465872A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT4100177 1977-01-12

Publications (1)

Publication Number Publication Date
ES465872A1 true ES465872A1 (en) 1979-01-01

Family

ID=11249971

Family Applications (1)

Application Number Title Priority Date Filing Date
ES465872A Expired ES465872A1 (en) 1977-01-12 1978-01-10 1-phenoxy-3-t-butylaminopropan-2-ols

Country Status (8)

Country Link
JP (1) JPS53111023A (en)
AT (1) ATA20678A (en)
BE (1) BE862680A (en)
DE (1) DE2758868A1 (en)
ES (1) ES465872A1 (en)
FR (1) FR2377372A1 (en)
GB (1) GB1563469A (en)
NL (1) NL7800215A (en)

Also Published As

Publication number Publication date
DE2758868A1 (en) 1978-07-13
JPS53111023A (en) 1978-09-28
NL7800215A (en) 1978-07-14
GB1563469A (en) 1980-03-26
BE862680A (en) 1978-05-02
FR2377372A1 (en) 1978-08-11
ATA20678A (en) 1979-01-15

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