ES464611A1 - Procedimiento para la obtencion de nuevos derivados del imidazol. - Google Patents

Procedimiento para la obtencion de nuevos derivados del imidazol.

Info

Publication number
ES464611A1
ES464611A1 ES464611A ES464611A ES464611A1 ES 464611 A1 ES464611 A1 ES 464611A1 ES 464611 A ES464611 A ES 464611A ES 464611 A ES464611 A ES 464611A ES 464611 A1 ES464611 A1 ES 464611A1
Authority
ES
Spain
Prior art keywords
substituted
unsubstituted
radical
het
acid addition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES464611A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES464611A1 publication Critical patent/ES464611A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/74—Naphthothiophenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedimiento para la obtención de nuevos derivados del imidazol de fórmula general I ***(Ver fórmula I)donde Het significa 1H-imidazol-1-ilo insustituido o sustituido por alquilo inferioruno de los símbolos X e Y significa el resto epitio-S- o el grupo etenileno -CH=CH- y el otro el enlace directo y n es 1 hasta 4y los anillos AB y C en caso dado están sustituidos o bien adicionalmente sustituidosy sus sales están sustituidos o bien adicionalmente sustituidosy sus sales de adición de un ácidocaracterizado porque a) un éster reactivo de un compuesto hidroxi de fórmula general II***(Ver fórmula II)
ES464611A 1976-12-01 1977-11-30 Procedimiento para la obtencion de nuevos derivados del imidazol. Expired ES464611A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU76303 1976-12-01

Publications (1)

Publication Number Publication Date
ES464611A1 true ES464611A1 (es) 1978-09-01

Family

ID=19728422

Family Applications (1)

Application Number Title Priority Date Filing Date
ES464611A Expired ES464611A1 (es) 1976-12-01 1977-11-30 Procedimiento para la obtencion de nuevos derivados del imidazol.

Country Status (17)

Country Link
US (1) US4171366A (es)
JP (1) JPS5368776A (es)
AT (1) AT361469B (es)
AU (1) AU517512B2 (es)
BE (1) BE861337A (es)
CA (1) CA1097351A (es)
DE (1) DE2753054A1 (es)
DK (1) DK531977A (es)
ES (1) ES464611A1 (es)
FI (1) FI773593A (es)
FR (1) FR2372829A1 (es)
GB (1) GB1590648A (es)
NL (1) NL7713241A (es)
NO (1) NO146600C (es)
NZ (1) NZ185824A (es)
SE (1) SE7713574L (es)
ZA (1) ZA777129B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8003141A (nl) * 1980-05-30 1982-01-04 Akzo Nv Biologisch aktieve tricyclische aminen.
GB8726505D0 (en) * 1987-11-12 1987-12-16 Ici Plc Naphtho(2 1-b)furan derivatives
JPH0249772A (ja) * 1988-04-07 1990-02-20 Glaxo Group Ltd イミダゾール誘導体
GB9407919D0 (en) * 1994-04-21 1994-06-15 Glaxo Group Ltd Chemical compounds
US9216977B2 (en) 2009-10-22 2015-12-22 The University Of North Carolina At Chapel Hill Antofine and cryptopleurine derivatives as anticancer agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903092A (en) * 1966-03-02 1975-09-02 Aspro Nicholas Ltd 2-Tertiaryamino-1-(benzo{8 b{9 thienyl)ethanols
SE7600674L (sv) * 1975-02-05 1976-08-06 Rohm & Haas Fungicider

Also Published As

Publication number Publication date
US4171366A (en) 1979-10-16
NZ185824A (en) 1980-08-26
NO774101L (no) 1978-06-02
AU517512B2 (en) 1981-08-06
AT361469B (de) 1981-03-10
NO146600C (no) 1982-11-03
GB1590648A (en) 1981-06-03
ATA857177A (de) 1980-08-15
ZA777129B (en) 1978-09-27
DE2753054A1 (de) 1978-06-08
FI773593A (fi) 1978-06-02
BE861337A (fr) 1978-05-30
CA1097351A (en) 1981-03-10
FR2372829A1 (fr) 1978-06-30
AU3108777A (en) 1979-06-07
JPS5368776A (en) 1978-06-19
DK531977A (da) 1978-06-02
NL7713241A (es) 1978-06-05
NO146600B (no) 1982-07-26
SE7713574L (sv) 1978-06-02
FR2372829B1 (es) 1982-06-04

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