ES463785A1 - Un procedimiento para preparar compuestos acepina - Google Patents
Un procedimiento para preparar compuestos acepinaInfo
- Publication number
- ES463785A1 ES463785A1 ES463785A ES463785A ES463785A1 ES 463785 A1 ES463785 A1 ES 463785A1 ES 463785 A ES463785 A ES 463785A ES 463785 A ES463785 A ES 463785A ES 463785 A1 ES463785 A1 ES 463785A1
- Authority
- ES
- Spain
- Prior art keywords
- decahydrocyclopent
- azepines
- analgesics
- aryl
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/32—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedimiento para preparar ciertas 2-substituido-5a-aril-decahidrociclopent (c) azepinas que pueden considerarse como relacionadas estructuralmente con ciertas estructuras parciales de la morfina, tales como los morfinanos, benzomorfanos, y derivados de isoquinolina. Los compuestos de la fórmula (i) no e han descrito hasta ahora, así como no hay disponible ningún método para su preparación. Además, los compuestos de la fórmula (i) exhiben una variación impredecible en las propiedades antagonistas y agonistas analgésicas, con posibilidad disminuida de dependencia física.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/737,957 US4141893A (en) | 1976-11-02 | 1976-11-02 | Decahydrocyclopent[c]azepines |
Publications (1)
Publication Number | Publication Date |
---|---|
ES463785A1 true ES463785A1 (es) | 1979-10-16 |
Family
ID=24965975
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES463785A Expired ES463785A1 (es) | 1976-11-02 | 1977-11-02 | Un procedimiento para preparar compuestos acepina |
ES472121A Expired ES472121A1 (es) | 1976-11-02 | 1978-07-27 | Un procedimiento para preparar compuestos azepina. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES472121A Expired ES472121A1 (es) | 1976-11-02 | 1978-07-27 | Un procedimiento para preparar compuestos azepina. |
Country Status (25)
Country | Link |
---|---|
US (1) | US4141893A (es) |
JP (1) | JPS5356682A (es) |
AT (1) | AT359067B (es) |
AU (1) | AU514786B2 (es) |
BE (1) | BE860313A (es) |
BG (1) | BG28418A3 (es) |
CA (1) | CA1094554A (es) |
DD (1) | DD133796A5 (es) |
DE (1) | DE2748467A1 (es) |
DK (1) | DK485377A (es) |
ES (2) | ES463785A1 (es) |
FR (1) | FR2369269A1 (es) |
GB (1) | GB1585297A (es) |
GR (1) | GR70054B (es) |
IE (1) | IE45900B1 (es) |
IL (1) | IL53237A0 (es) |
NL (1) | NL7712051A (es) |
NZ (1) | NZ185538A (es) |
PL (2) | PL108031B1 (es) |
PT (1) | PT67193B (es) |
RO (1) | RO73087B (es) |
SE (1) | SE7712217L (es) |
SU (1) | SU727141A3 (es) |
YU (1) | YU257477A (es) |
ZA (1) | ZA776499B (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3704661A1 (de) * | 1987-02-14 | 1988-08-25 | Hoechst Ag | Annelierte azepinon- und azocinon-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung, sowie zwischenprodukte bei ihrer herstellung |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA734895B (en) * | 1972-07-20 | 1974-06-26 | Du Pont | Analgesigs and/or narcotic antagonists |
US4001248A (en) * | 1974-06-07 | 1977-01-04 | Eli Lilly And Company | N-cycloalkylmethyl decahydroisoquinolines |
US4001247A (en) * | 1974-06-07 | 1977-01-04 | Eli Lilly And Company | 1-ethyl 3a-(substituted-phenyl) decahydroisoquinoline |
-
1976
- 1976-11-02 US US05/737,957 patent/US4141893A/en not_active Expired - Lifetime
-
1977
- 1977-10-26 PT PT67193A patent/PT67193B/pt unknown
- 1977-10-27 GB GB44730/77A patent/GB1585297A/en not_active Expired
- 1977-10-27 CA CA289,696A patent/CA1094554A/en not_active Expired
- 1977-10-27 IL IL53237A patent/IL53237A0/xx unknown
- 1977-10-27 NZ NZ185538A patent/NZ185538A/xx unknown
- 1977-10-27 YU YU02574/77A patent/YU257477A/xx unknown
- 1977-10-28 SE SE7712217A patent/SE7712217L/xx unknown
- 1977-10-28 IE IE2205/77A patent/IE45900B1/en unknown
- 1977-10-28 DE DE19772748467 patent/DE2748467A1/de not_active Withdrawn
- 1977-10-28 FR FR7732775A patent/FR2369269A1/fr active Granted
- 1977-10-28 BE BE1008482A patent/BE860313A/xx unknown
- 1977-11-01 DK DK485377A patent/DK485377A/da unknown
- 1977-11-01 AU AU30234/77A patent/AU514786B2/en not_active Expired
- 1977-11-01 ZA ZA00776499A patent/ZA776499B/xx unknown
- 1977-11-01 NL NL7712051A patent/NL7712051A/xx not_active Application Discontinuation
- 1977-11-01 BG BG7737701A patent/BG28418A3/xx unknown
- 1977-11-02 ES ES463785A patent/ES463785A1/es not_active Expired
- 1977-11-02 RO RO7792003A patent/RO73087B/ro unknown
- 1977-11-02 AT AT782077A patent/AT359067B/de not_active IP Right Cessation
- 1977-11-02 SU SU772538948A patent/SU727141A3/ru active
- 1977-11-02 PL PL1977201884A patent/PL108031B1/pl unknown
- 1977-11-02 DD DD7700201830A patent/DD133796A5/xx unknown
- 1977-11-02 PL PL1977215629A patent/PL112151B1/pl unknown
- 1977-11-02 JP JP13211077A patent/JPS5356682A/ja active Pending
- 1977-12-29 GR GR54665A patent/GR70054B/el unknown
-
1978
- 1978-07-27 ES ES472121A patent/ES472121A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
PT67193A (en) | 1977-11-01 |
AU514786B2 (en) | 1981-02-26 |
BE860313A (fr) | 1978-04-28 |
DE2748467A1 (de) | 1978-05-03 |
SU727141A3 (ru) | 1980-04-05 |
IL53237A0 (en) | 1977-12-30 |
AU3023477A (en) | 1979-05-10 |
YU257477A (en) | 1983-01-21 |
GB1585297A (en) | 1981-02-25 |
ATA782077A (de) | 1980-03-15 |
FR2369269B1 (es) | 1980-05-16 |
AT359067B (de) | 1980-10-27 |
ES472121A1 (es) | 1979-04-01 |
PT67193B (en) | 1979-03-22 |
PL112151B1 (en) | 1980-09-30 |
IE45900B1 (en) | 1982-12-29 |
SE7712217L (sv) | 1978-05-03 |
PL108031B1 (pl) | 1980-03-31 |
DK485377A (da) | 1978-05-03 |
FR2369269A1 (fr) | 1978-05-26 |
NZ185538A (en) | 1979-06-08 |
NL7712051A (nl) | 1978-05-05 |
JPS5356682A (en) | 1978-05-23 |
BG28418A3 (en) | 1980-04-15 |
PL201884A1 (pl) | 1978-12-04 |
DD133796A5 (de) | 1979-01-24 |
IE45900L (en) | 1978-05-02 |
CA1094554A (en) | 1981-01-27 |
ZA776499B (en) | 1979-06-27 |
US4141893A (en) | 1979-02-27 |
RO73087B (ro) | 1981-08-20 |
GR70054B (es) | 1982-07-26 |
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