ES462990A1 - Un procedimiento para la preparacion del yoduro de 2-(2-fu- roil)-1,4-dimetilpiridinio - Google Patents
Un procedimiento para la preparacion del yoduro de 2-(2-fu- roil)-1,4-dimetilpiridinioInfo
- Publication number
- ES462990A1 ES462990A1 ES462990A ES462990A ES462990A1 ES 462990 A1 ES462990 A1 ES 462990A1 ES 462990 A ES462990 A ES 462990A ES 462990 A ES462990 A ES 462990A ES 462990 A1 ES462990 A1 ES 462990A1
- Authority
- ES
- Spain
- Prior art keywords
- furoyl
- methylpyridine
- methyl iodide
- quaternary salt
- iodide quaternary
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Un procedimiento para la preparación del yoduro de 2-(2- furoil)¿1,4-dimetilpiridinio de fórmula I. **(Fórmula)** caracterizado porque en una primera etapa de síntesis se hace reaccionar bajo atmósfera de nitrógeno, la 2-ciano-4- metilpiridina con una disolución etérea de 2-furil-litio recientemente preparado, y porque tras de una hidrólisis ácida se obtiene la 2-(2-furoil)-4-metilpiridina (II). **(Fórmula)** la cual por calentamiento en presencia de un halógenuro de metilo, por ejemplo el ioduro de metilo, se convierte en el compuesto de fórmula I.
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES462990A ES462990A1 (es) | 1977-10-07 | 1977-10-07 | Un procedimiento para la preparacion del yoduro de 2-(2-fu- roil)-1,4-dimetilpiridinio |
DE19782843495 DE2843495A1 (de) | 1977-10-07 | 1978-10-05 | 2-(2-furoyl)-1,4-dimethylpyridin, 2-(2-furoyl)-1,4-dimethylpyridiniumjodid und verfahren zu ihrer herstellung |
GB7839498A GB2005273B (en) | 1977-10-07 | 1978-10-05 | Pyridine compounds and corresponding methyl halides methods of preparation and pharmaceutical compositions containing the same |
CH1041878A CH638518A5 (de) | 1977-10-07 | 1978-10-06 | 2-(2-furoyl)-4-methylpyridin und verfahren zu seiner herstellung. |
FR7828583A FR2405255B1 (fr) | 1977-10-07 | 1978-10-06 | L'iodure de 2-(2-furoyl)-1,4-dimethylpyridinium, son procede de preparation, et son application en tant que medicament |
JP12349378A JPS5479284A (en) | 1977-10-07 | 1978-10-06 | 22*22furoyl**1*44dimethyl pyridinium iodide and its manufacture |
US05/949,021 US4173705A (en) | 1977-10-07 | 1978-10-06 | 2-(2-Furoyl)-4-methylpyridine and its methyl iodide quaternary salt |
PT68627A PT68627A (en) | 1977-10-07 | 1978-10-06 | Process for the preparation of 2-(2-furoyl)-1,4-dimethyl-pyridinium iodide |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES462990A ES462990A1 (es) | 1977-10-07 | 1977-10-07 | Un procedimiento para la preparacion del yoduro de 2-(2-fu- roil)-1,4-dimetilpiridinio |
Publications (1)
Publication Number | Publication Date |
---|---|
ES462990A1 true ES462990A1 (es) | 1979-01-01 |
Family
ID=8474648
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES462990A Expired ES462990A1 (es) | 1977-10-07 | 1977-10-07 | Un procedimiento para la preparacion del yoduro de 2-(2-fu- roil)-1,4-dimetilpiridinio |
Country Status (8)
Country | Link |
---|---|
US (1) | US4173705A (es) |
JP (1) | JPS5479284A (es) |
CH (1) | CH638518A5 (es) |
DE (1) | DE2843495A1 (es) |
ES (1) | ES462990A1 (es) |
FR (1) | FR2405255B1 (es) |
GB (1) | GB2005273B (es) |
PT (1) | PT68627A (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5495828A (en) * | 1978-01-10 | 1979-07-28 | Nissan Motor Co Ltd | Exhaust recirculation system of internal combustion engine |
KR102560825B1 (ko) * | 2018-04-30 | 2023-07-31 | 현대자동차주식회사 | 리튬 이차전지 및 그 제조방법 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE792042A (fr) * | 1971-11-30 | 1973-05-29 | Ciba Geigy | Procede de preparation de nouvelles alcenylene-amines substituees en 3 |
-
1977
- 1977-10-07 ES ES462990A patent/ES462990A1/es not_active Expired
-
1978
- 1978-10-05 GB GB7839498A patent/GB2005273B/en not_active Expired
- 1978-10-05 DE DE19782843495 patent/DE2843495A1/de not_active Withdrawn
- 1978-10-06 CH CH1041878A patent/CH638518A5/de not_active IP Right Cessation
- 1978-10-06 JP JP12349378A patent/JPS5479284A/ja active Pending
- 1978-10-06 FR FR7828583A patent/FR2405255B1/fr not_active Expired
- 1978-10-06 US US05/949,021 patent/US4173705A/en not_active Expired - Lifetime
- 1978-10-06 PT PT68627A patent/PT68627A/pt unknown
Also Published As
Publication number | Publication date |
---|---|
FR2405255B1 (fr) | 1985-10-04 |
PT68627A (en) | 1978-11-01 |
DE2843495A1 (de) | 1979-04-12 |
GB2005273A (en) | 1979-04-19 |
GB2005273B (en) | 1982-02-17 |
CH638518A5 (de) | 1983-09-30 |
FR2405255A1 (fr) | 1979-05-04 |
US4173705A (en) | 1979-11-06 |
JPS5479284A (en) | 1979-06-25 |
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