ES459070A1 - Azatetracyclic compounds - Google Patents

Azatetracyclic compounds

Info

Publication number
ES459070A1
ES459070A1 ES459070A ES459070A ES459070A1 ES 459070 A1 ES459070 A1 ES 459070A1 ES 459070 A ES459070 A ES 459070A ES 459070 A ES459070 A ES 459070A ES 459070 A1 ES459070 A1 ES 459070A1
Authority
ES
Spain
Prior art keywords
compounds
image
formula
azatetracyclic
azatetracyclic compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES459070A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES459070A1 publication Critical patent/ES459070A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/32—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/14—[b,f]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/74—Naphthothiophenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/14—[b,f]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes

Abstract

Azatetracyclic compounds of formula I < IMAGE > are obtained by reaction of a reactive diester of a diethanol of formula II < IMAGE > with a compound of formula III < IMAGE > The meaning of the individual symbols is given in Claim 1. The novel compounds may be used as tranquillizing, antipsychotic and sedative compounds for the treatment of anxiety (agitation) states.
ES459070A 1976-05-26 1977-05-24 Azatetracyclic compounds Expired ES459070A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH665076A CH624105A5 (en) 1976-05-26 1976-05-26 Process for the preparation of novel azatetracyclic compounds

Publications (1)

Publication Number Publication Date
ES459070A1 true ES459070A1 (en) 1978-04-16

Family

ID=4312888

Family Applications (1)

Application Number Title Priority Date Filing Date
ES459070A Expired ES459070A1 (en) 1976-05-26 1977-05-24 Azatetracyclic compounds

Country Status (30)

Country Link
JP (1) JPS52144687A (en)
AR (2) AR227608A1 (en)
AT (1) AT356114B (en)
AU (1) AU510471B2 (en)
BE (1) BE855009A (en)
CA (1) CA1104566A (en)
CH (2) CH624105A5 (en)
CS (2) CS225103B2 (en)
CY (1) CY1211A (en)
DD (1) DD131169A5 (en)
DE (1) DE2723105A1 (en)
DK (1) DK150301C (en)
ES (1) ES459070A1 (en)
FI (1) FI64582C (en)
FR (1) FR2352816A1 (en)
GB (1) GB1578266A (en)
GR (1) GR72092B (en)
HK (1) HK8784A (en)
HU (1) HU177417B (en)
IE (1) IE45204B1 (en)
IL (1) IL52168A (en)
KE (1) KE3339A (en)
MY (1) MY8500099A (en)
NL (1) NL7705707A (en)
NO (1) NO148489C (en)
NZ (1) NZ184191A (en)
PT (1) PT66588B (en)
SE (1) SE427354B (en)
SG (1) SG63683G (en)
ZA (1) ZA773161B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3069086D1 (en) * 1979-12-10 1984-10-04 Ciba Geigy Ag AZATETRACYCLIC CARBONITRILES

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL178593C (en) * 1974-01-31 1986-04-16 Akzo Nv PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION BASED ON A TETRACYCLIC COMPOUND AND METHOD FOR PREPARING THE TETRACYCLIC COMPOUNDS TO BE USED THEREOF
CH592095A5 (en) * 1974-02-22 1977-10-14 Ciba Geigy Ag

Also Published As

Publication number Publication date
PT66588A (en) 1977-06-01
ZA773161B (en) 1978-04-26
DE2723105C2 (en) 1987-03-12
JPS52144687A (en) 1977-12-02
CH624105A5 (en) 1981-07-15
AT356114B (en) 1980-04-10
FI64582B (en) 1983-08-31
CH624106A5 (en) 1981-07-15
HK8784A (en) 1984-02-10
AU510471B2 (en) 1980-06-26
AR228124A1 (en) 1983-01-31
IE45204L (en) 1977-11-26
JPH0141627B2 (en) 1989-09-06
FR2352816A1 (en) 1977-12-23
NO148489C (en) 1983-10-19
CS225103B2 (en) 1984-02-13
DE2723105A1 (en) 1977-12-15
NO148489B (en) 1983-07-11
SE427354B (en) 1983-03-28
PT66588B (en) 1978-10-23
NO771830L (en) 1977-11-29
GR72092B (en) 1983-09-13
FR2352816B1 (en) 1980-01-18
MY8500099A (en) 1985-12-31
AU2547377A (en) 1978-11-30
SG63683G (en) 1984-07-27
CY1211A (en) 1984-04-06
DD131169A5 (en) 1978-06-07
IE45204B1 (en) 1982-07-14
FI771651A (en) 1977-11-27
ATA372577A (en) 1979-09-15
NZ184191A (en) 1979-12-11
IL52168A0 (en) 1977-07-31
DK229977A (en) 1977-11-27
IL52168A (en) 1981-07-31
BE855009A (en) 1977-11-25
FI64582C (en) 1983-12-12
NL7705707A (en) 1977-11-29
DK150301C (en) 1988-01-04
AR227608A1 (en) 1982-11-30
SE7706120L (en) 1977-11-27
DK150301B (en) 1987-02-02
HU177417B (en) 1981-10-28
KE3339A (en) 1983-11-25
GB1578266A (en) 1980-11-05
CS225106B2 (en) 1984-02-13
CA1104566A (en) 1981-07-07

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990601