ES458791A1 - Un procedimiento para la preparacion de nuevos derivados de naftilo. - Google Patents
Un procedimiento para la preparacion de nuevos derivados de naftilo.Info
- Publication number
- ES458791A1 ES458791A1 ES458791A ES458791A ES458791A1 ES 458791 A1 ES458791 A1 ES 458791A1 ES 458791 A ES458791 A ES 458791A ES 458791 A ES458791 A ES 458791A ES 458791 A1 ES458791 A1 ES 458791A1
- Authority
- ES
- Spain
- Prior art keywords
- naphthyl
- butanes
- acyloxy
- substituted
- optical isomers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 235000013844 butane Nutrition 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 2
- 230000003287 optical effect Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/08—Six-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/10—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond
- C07C67/11—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond being mineral ester groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
- C07C69/12—Acetic acid esters
- C07C69/14—Acetic acid esters of monohydroxylic compounds
- C07C69/145—Acetic acid esters of monohydroxylic compounds of unsaturated alcohols
- C07C69/157—Acetic acid esters of monohydroxylic compounds of unsaturated alcohols containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/34—Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
- C07C69/92—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un procedimiento para la preparación de nuevos derivados de naftilo de fórmula (II) Donde R1 es un átomo de cloro o bromo o un grupo metoxi, metilito o alquilo C1-4; R2 es un grupo tal que R2CO2H es un ácido farmacéuticamente aceptable de hasta 12 átomos de carbono; n es 1 o 2 y la línea de puntos representa un doble enlace opcionalmente presente; *** Ver imagen 01
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB19653/76A GB1538473A (en) | 1976-05-13 | 1976-05-13 | Naphthalene derivatives |
| GB4093776 | 1976-10-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES458791A1 true ES458791A1 (es) | 1978-08-01 |
Family
ID=26254167
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES458791A Expired ES458791A1 (es) | 1976-05-13 | 1977-05-13 | Un procedimiento para la preparacion de nuevos derivados de naftilo. |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US4299844A (es) |
| JP (1) | JPS52137456A (es) |
| AT (1) | AT356088B (es) |
| AU (1) | AU510882B2 (es) |
| CA (1) | CA1111440A (es) |
| CH (1) | CH630887A5 (es) |
| DE (1) | DE2721207A1 (es) |
| DK (1) | DK208677A (es) |
| ES (1) | ES458791A1 (es) |
| FR (1) | FR2351084A1 (es) |
| IE (1) | IE45417B1 (es) |
| IL (1) | IL52006A0 (es) |
| NL (1) | NL7705242A (es) |
| SE (1) | SE7705473L (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2014993B (en) * | 1977-11-03 | 1982-05-12 | Beecham Group Ltd | Chemical compounds |
| US4709082A (en) * | 1984-10-25 | 1987-11-24 | Nissan Chemical Industries, Ltd. | 2-phenylpropionic acid esters, method for optical resolution thereof and optically active substance thereof |
| US5026759A (en) * | 1985-05-08 | 1991-06-25 | Du Pont Merck Pharmaceutical | 2-substituted-1-naphthols as 5-lipoxygenase inhibitors |
| WO1994010116A1 (en) * | 1992-10-26 | 1994-05-11 | Sumitomo Chemical Company, Limited | Acetylene derivative, process for producing the same, liquid crystal composition containing the same as active ingredient, and liquid crystal element made therefrom |
| US5756851A (en) * | 1996-10-21 | 1998-05-26 | Albemarle Corporation | Production of nabumetone or precursors thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4035406A (en) * | 1973-08-20 | 1977-07-12 | Sandoz, Inc. | 4-alkyl-4-naphthyl-butanes |
| GB1474377A (en) * | 1973-09-11 | 1977-05-25 | Beecham Group Ltd | Naphthalene derivatives |
-
1977
- 1977-05-04 IL IL52006A patent/IL52006A0/xx unknown
- 1977-05-05 CA CA277,757A patent/CA1111440A/en not_active Expired
- 1977-05-09 FR FR7714052A patent/FR2351084A1/fr active Granted
- 1977-05-10 SE SE7705473A patent/SE7705473L/xx not_active Application Discontinuation
- 1977-05-11 AU AU25077/77A patent/AU510882B2/en not_active Expired
- 1977-05-11 AT AT336977A patent/AT356088B/de not_active IP Right Cessation
- 1977-05-11 DE DE19772721207 patent/DE2721207A1/de not_active Withdrawn
- 1977-05-12 CH CH597777A patent/CH630887A5/de not_active IP Right Cessation
- 1977-05-12 JP JP5483977A patent/JPS52137456A/ja active Pending
- 1977-05-12 NL NL7705242A patent/NL7705242A/xx not_active Application Discontinuation
- 1977-05-12 IE IE966/77A patent/IE45417B1/en unknown
- 1977-05-12 DK DK208677A patent/DK208677A/da not_active Application Discontinuation
- 1977-05-13 ES ES458791A patent/ES458791A1/es not_active Expired
-
1979
- 1979-07-09 US US06/055,613 patent/US4299844A/en not_active Expired - Lifetime
-
1981
- 1981-07-27 US US06/287,260 patent/US4426392A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATA336977A (de) | 1979-09-15 |
| CH630887A5 (de) | 1982-07-15 |
| DE2721207A1 (de) | 1977-11-24 |
| IL52006A0 (en) | 1977-07-31 |
| IE45417L (en) | 1977-11-13 |
| AT356088B (de) | 1980-04-10 |
| AU510882B2 (en) | 1980-07-17 |
| SE7705473L (sv) | 1977-11-14 |
| DK208677A (da) | 1977-11-14 |
| US4426392A (en) | 1984-01-17 |
| NL7705242A (nl) | 1977-11-15 |
| IE45417B1 (en) | 1982-08-25 |
| CA1111440A (en) | 1981-10-27 |
| JPS52137456A (en) | 1977-11-16 |
| AU2507777A (en) | 1978-11-16 |
| FR2351084B1 (es) | 1980-03-07 |
| US4299844A (en) | 1981-11-10 |
| FR2351084A1 (fr) | 1977-12-09 |
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