ES458042A1 - Nuevo procedimiento para la sintesis de la 1-ciano-2-metil- 3-(2-(((5-metil-imidazol-4-il-)metil)tio)etil)-guanidina. - Google Patents

Nuevo procedimiento para la sintesis de la 1-ciano-2-metil- 3-(2-(((5-metil-imidazol-4-il-)metil)tio)etil)-guanidina.

Info

Publication number
ES458042A1
ES458042A1 ES458042A ES458042A ES458042A1 ES 458042 A1 ES458042 A1 ES 458042A1 ES 458042 A ES458042 A ES 458042A ES 458042 A ES458042 A ES 458042A ES 458042 A1 ES458042 A1 ES 458042A1
Authority
ES
Spain
Prior art keywords
guanidine
methyl
thiol
cyano
deriv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES458042A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ricorvi S A
Original Assignee
Ricorvi S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ricorvi S A filed Critical Ricorvi S A
Priority to ES458042A priority Critical patent/ES458042A1/es
Priority to FR7732156A priority patent/FR2386525A1/fr
Priority to PT67377A priority patent/PT67377B/pt
Publication of ES458042A1 publication Critical patent/ES458042A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA SINTESIS DE LA 1-CIANO-2-METIL-3-(2-((5-METIL-IMIDAZOL-4-IL-)METIL)TIO)ETIL)-GUANIDINA CUYA FORMULA ES: **FORMULA** SE HACE REACCIONAR EL 4-CLOROMETIL-5-METIL-IMIDAZOL CON EL 1-CIANO-2-METIL-3-((2-TIOL)ETIL)-GUANIDINA EN MEDIO ALCALINO, EN FORMA DE SAL DE TIOL. POSEE APLICACIONES TERAPEUTICAS.
ES458042A 1977-04-06 1977-04-06 Nuevo procedimiento para la sintesis de la 1-ciano-2-metil- 3-(2-(((5-metil-imidazol-4-il-)metil)tio)etil)-guanidina. Expired ES458042A1 (es)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES458042A ES458042A1 (es) 1977-04-06 1977-04-06 Nuevo procedimiento para la sintesis de la 1-ciano-2-metil- 3-(2-(((5-metil-imidazol-4-il-)metil)tio)etil)-guanidina.
FR7732156A FR2386525A1 (fr) 1977-04-06 1977-10-17 Procede pour la synthese de la 1-cyano-2-methyl-3- (2- (((5-methyl-imidazol-4-yl)methyl)thio)ethyl)-guanidine
PT67377A PT67377B (fr) 1977-04-06 1977-12-07 Nouveau procede pour la synthese de la 1-cyano-2-methyl-3-(2-<(-5-methyl-imidazol-4-yl)thio>ethyl)-guanidine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES458042A ES458042A1 (es) 1977-04-06 1977-04-06 Nuevo procedimiento para la sintesis de la 1-ciano-2-metil- 3-(2-(((5-metil-imidazol-4-il-)metil)tio)etil)-guanidina.

Publications (1)

Publication Number Publication Date
ES458042A1 true ES458042A1 (es) 1978-08-16

Family

ID=8473606

Family Applications (1)

Application Number Title Priority Date Filing Date
ES458042A Expired ES458042A1 (es) 1977-04-06 1977-04-06 Nuevo procedimiento para la sintesis de la 1-ciano-2-metil- 3-(2-(((5-metil-imidazol-4-il-)metil)tio)etil)-guanidina.

Country Status (3)

Country Link
ES (1) ES458042A1 (es)
FR (1) FR2386525A1 (es)
PT (1) PT67377B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI63753C (fi) * 1980-08-21 1987-02-19 Orion Yhtymae Oy Foerfarande foer framstaellning av kristallint simetidin.
IT1215344B (it) * 1987-01-27 1990-02-08 Dessy S R L Ora Recordati Farm Procedimento per la preparazione di composti ad attivita' anti-ulcera.
US5808090A (en) * 1996-02-22 1998-09-15 Endo Pharmaceuticals Inc. Process for preventing precipitation in cimetidine injection solutions

Also Published As

Publication number Publication date
PT67377A (fr) 1978-01-01
PT67377B (fr) 1979-05-18
FR2386525A1 (fr) 1978-11-03

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