ES455696A1 - Procedimiento de produccion de una solucion estable e inyec-table que contenga una sulfonamida y un potenciador. - Google Patents
Procedimiento de produccion de una solucion estable e inyec-table que contenga una sulfonamida y un potenciador.Info
- Publication number
- ES455696A1 ES455696A1 ES455696A ES455696A ES455696A1 ES 455696 A1 ES455696 A1 ES 455696A1 ES 455696 A ES455696 A ES 455696A ES 455696 A ES455696 A ES 455696A ES 455696 A1 ES455696 A1 ES 455696A1
- Authority
- ES
- Spain
- Prior art keywords
- potentiator
- sulphonamide
- producing stable
- stable solutions
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Procedimiento de producción de una solución estable e inyectable que contenga una sulfonamida y un potenciador, caracterizado porque la sulfonamida, bajo la forma de su sal dietanolamina, y una sal del potenciador, son disueltas en una mezcla de agua, propilenoglicol y N-metilpirrolidona, siendo el contenido acuoso del preparado del 10% al 50% p/v, el contenido en propilenoglicol del 15% al 30% p/v y el contenido en N-metilpirrolidona del 20% al 40% p/v; seguidamente se ajusta el pH entre 5,5 y 7,5.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK49776AA DK136934B (da) | 1976-02-06 | 1976-02-06 | Fremgangsmåde til fremstilling af en klar, stabil, injicerbar opløsning indeholdende et sulfonamid og en potentiator. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES455696A1 true ES455696A1 (es) | 1978-01-01 |
Family
ID=8094229
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES455696A Expired ES455696A1 (es) | 1976-02-06 | 1977-02-05 | Procedimiento de produccion de una solucion estable e inyec-table que contenga una sulfonamida y un potenciador. |
Country Status (15)
Country | Link |
---|---|
US (1) | US4133879A (es) |
AT (1) | AT347579B (es) |
AU (1) | AU512299B2 (es) |
BE (1) | BE851060A (es) |
CA (1) | CA1092970A (es) |
DE (1) | DE2704708A1 (es) |
DK (1) | DK136934B (es) |
ES (1) | ES455696A1 (es) |
FR (1) | FR2340100A1 (es) |
GB (1) | GB1522571A (es) |
NL (1) | NL186847C (es) |
NO (1) | NO145043C (es) |
NZ (1) | NZ183224A (es) |
SE (1) | SE436396B (es) |
ZA (1) | ZA77531B (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2631780C3 (de) * | 1976-07-15 | 1981-11-19 | Basf Ag, 6700 Ludwigshafen | Sulfonamid-Trimethoprim-Lösungen |
EP0007591B1 (de) * | 1978-08-01 | 1982-07-28 | Ciba-Geigy Ag | Stabile flüssige Arzneimittelformulierung auf Basis von 2,6-Diamino-5-(3',4',5'-trimethoxybenzyl)-pyrimidin(Trimethoprim) und einem Sulfonamid, Verfahren zu ihrer Herstellung und ihre Verwendung |
IE49934B1 (en) * | 1979-07-02 | 1986-01-08 | Pfizer | Long acting sulfonamide injectable compositions |
ATE3750T1 (de) * | 1979-07-05 | 1983-06-15 | Pfizer Inc. | Sulfonamidloesungen. |
HU180740B (en) * | 1979-11-27 | 1983-04-29 | Egyt Gyogyszervegyeszeti Gyar | Process for producing sulfonamide-containing,injectable pharmaceutical composition of prolongated activity |
HU212498B (en) | 1992-11-06 | 1996-07-29 | Egyt Gyogyszervegyeszeti Gyar | Process for producing water-soluble pharmaceutical compositions, containing sulfachlorpyridazin-sodium and trimethoprim |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH544053A (de) * | 1966-05-09 | 1973-11-15 | Hoffmann La Roche | Verfahren zur Herstellung von Sulfonamidderivaten |
ZM3271A1 (en) * | 1970-03-13 | 1972-10-23 | Wellcome Found | Improvements in or relating to injectable therapeutic compositions |
US3985876A (en) * | 1973-01-05 | 1976-10-12 | Burroughs Wellcome Co. | Chemotherapeutic solutions containing a sulphur and a salt of a 2,4-diamino-5-benzylpyrimidine |
IL46406A (en) * | 1975-01-08 | 1977-08-31 | Abic Ltd | The water-floating mixture containing robinidin |
-
1976
- 1976-02-06 DK DK49776AA patent/DK136934B/da not_active IP Right Cessation
-
1977
- 1977-01-31 GB GB3885/77A patent/GB1522571A/en not_active Expired
- 1977-01-31 ZA ZA770531A patent/ZA77531B/xx unknown
- 1977-01-31 US US05/764,244 patent/US4133879A/en not_active Expired - Lifetime
- 1977-01-31 NZ NZ183224A patent/NZ183224A/xx unknown
- 1977-02-03 BE BE174638A patent/BE851060A/xx not_active IP Right Cessation
- 1977-02-03 AU AU21909/77A patent/AU512299B2/en not_active Expired
- 1977-02-03 CA CA271,020A patent/CA1092970A/en not_active Expired
- 1977-02-03 SE SE7701218A patent/SE436396B/xx not_active IP Right Cessation
- 1977-02-04 FR FR7703206A patent/FR2340100A1/fr active Granted
- 1977-02-04 DE DE19772704708 patent/DE2704708A1/de not_active Withdrawn
- 1977-02-04 AT AT73577A patent/AT347579B/de not_active IP Right Cessation
- 1977-02-04 NO NO770386A patent/NO145043C/no unknown
- 1977-02-05 ES ES455696A patent/ES455696A1/es not_active Expired
- 1977-02-07 NL NLAANVRAGE7701267,A patent/NL186847C/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU512299B2 (en) | 1980-10-02 |
NZ183224A (en) | 1979-10-25 |
AT347579B (de) | 1979-01-10 |
SE436396B (sv) | 1984-12-10 |
ZA77531B (en) | 1977-12-28 |
NO770386L (no) | 1977-08-09 |
NL7701267A (nl) | 1977-08-09 |
DK49776A (es) | 1977-08-07 |
FR2340100A1 (fr) | 1977-09-02 |
BE851060A (fr) | 1977-05-31 |
ATA73577A (de) | 1978-05-15 |
NO145043C (no) | 1982-01-27 |
FR2340100B1 (es) | 1981-07-10 |
US4133879A (en) | 1979-01-09 |
DE2704708A1 (de) | 1977-08-11 |
AU2190977A (en) | 1978-08-10 |
SE7701218L (sv) | 1977-08-07 |
NO145043B (no) | 1981-09-21 |
GB1522571A (en) | 1978-08-23 |
NL186847C (nl) | 1991-03-18 |
CA1092970A (en) | 1981-01-06 |
DK136934C (es) | 1982-03-22 |
DK136934B (da) | 1977-12-19 |
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