ES455064A1 - Nuevo procedimiento para la obtencion del acido (d)-2(6-me- toxi-2-naftil)-propionico. - Google Patents

Nuevo procedimiento para la obtencion del acido (d)-2(6-me- toxi-2-naftil)-propionico.

Info

Publication number
ES455064A1
ES455064A1 ES77455064A ES455064A ES455064A1 ES 455064 A1 ES455064 A1 ES 455064A1 ES 77455064 A ES77455064 A ES 77455064A ES 455064 A ES455064 A ES 455064A ES 455064 A1 ES455064 A1 ES 455064A1
Authority
ES
Spain
Prior art keywords
propanal
naphthyl
methoxy
isomer
give
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES77455064A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VALLES QUIMICA
Original Assignee
VALLES QUIMICA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by VALLES QUIMICA filed Critical VALLES QUIMICA
Priority to ES77455064A priority Critical patent/ES455064A1/es
Priority to DK179377A priority patent/DK179377A/da
Priority to FI771328A priority patent/FI771328A/fi
Priority to FR7735102A priority patent/FR2377370A1/fr
Publication of ES455064A1 publication Critical patent/ES455064A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C07C51/29—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with halogen-containing compounds which may be formed in situ
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings

Abstract

Nuevo procedimiento para la obtención del ácido (d)-2(6-metoxi-2-naftil)-propiónico, caracterizado por la realización de la siguiente sucesión de operaciones: a) Condensación del 2(6-metoxi-2-naftil)-propal racémico con la 5(alfa-feniletil)-semioxamacida dextrógira, en medio bencénico anhidro y en presencia de yodo como catalizador, para formar la mezcla diastereoisómera de semioxamazonas: **(Fórmula)** b) Resolución de la mezcla diastereoisómera de semioxamazonas obtenida, mediante recristalizaciones en dioxano, para separar el isómero d,d III puro, reservando las aguas madres conteniendo el isómero 1,d III para su recuperación si se desea; c) Hidrólisis del isómero d,d III separado bajo la acción del ácido sulfúrico al 20 % para liberar el isómero dextrogiro del 2(6-metoxi-2-naftil)-propanal; d) Oxidación del aldehido dextrógiro obtenido, utilizando como oxidante una solución de clorito sódico en presencia de ácido sulfámico, para obtener el producto final deseado (-acido 2(6-metoxi-2-naftil)-propiónico dextrógiro)).
ES77455064A 1977-01-17 1977-01-17 Nuevo procedimiento para la obtencion del acido (d)-2(6-me- toxi-2-naftil)-propionico. Expired ES455064A1 (es)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ES77455064A ES455064A1 (es) 1977-01-17 1977-01-17 Nuevo procedimiento para la obtencion del acido (d)-2(6-me- toxi-2-naftil)-propionico.
DK179377A DK179377A (da) 1977-01-17 1977-04-22 Fremgangsmaade til fremstilling af (d)-2(6-methoxy-2-naphthyl) -propionsyre
FI771328A FI771328A (fi) 1977-01-17 1977-04-26 Nytt foerfarande foer framstaellning av (d)-2(6-metoxi-2-naftyl)propionsyra
FR7735102A FR2377370A1 (fr) 1977-01-17 1977-11-15 Procede pour l'obtention de l'acide (d)-2(6-methoxy-2-naphtyl)-propionique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES77455064A ES455064A1 (es) 1977-01-17 1977-01-17 Nuevo procedimiento para la obtencion del acido (d)-2(6-me- toxi-2-naftil)-propionico.

Publications (1)

Publication Number Publication Date
ES455064A1 true ES455064A1 (es) 1978-02-01

Family

ID=8472965

Family Applications (1)

Application Number Title Priority Date Filing Date
ES77455064A Expired ES455064A1 (es) 1977-01-17 1977-01-17 Nuevo procedimiento para la obtencion del acido (d)-2(6-me- toxi-2-naftil)-propionico.

Country Status (4)

Country Link
DK (1) DK179377A (es)
ES (1) ES455064A1 (es)
FI (1) FI771328A (es)
FR (1) FR2377370A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0081993A2 (en) * 1981-12-11 1983-06-22 Syntex Pharmaceuticals International Limited Optically active alpha-substituted aryl ketones, their preparation and their use in preparing alpha-arylalkanoic acids

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5210258A (en) * 1981-12-11 1993-05-11 Syntex Pharmaceuticals International Ltd. Optically active alpha-naththylalkyl ketones
US4749804A (en) * 1981-12-11 1988-06-07 Syntex (U.S.A.) Inc. Preparation of stereoisomers of ketals

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0081993A2 (en) * 1981-12-11 1983-06-22 Syntex Pharmaceuticals International Limited Optically active alpha-substituted aryl ketones, their preparation and their use in preparing alpha-arylalkanoic acids
EP0081993A3 (en) * 1981-12-11 1984-01-11 Syntex Pharmaceuticals International Limited Optically active alpha-substituted aryl ketones, their preparation and their use in preparing alpha-arylalkanoic acids

Also Published As

Publication number Publication date
DK179377A (da) 1978-07-15
FI771328A (fi) 1978-07-15
FR2377370A1 (fr) 1978-08-11

Similar Documents

Publication Publication Date Title
EA200200016A1 (ru) Способ получения чистого циталопрама
ES2157293T3 (es) Preparacion de acidos carboxilicos c3-c6 alfa,beta-insaturados.
ES2074811T3 (es) Procedimiento para la obtencion de soluciones acuosas de peroxido de hidrogeno.
DK208089A (da) Fremgangsmaade til fremstilling af ferrichlorid ud fra fortyndet saltsyre
ES8101044A1 (es) Procedimiento para la depuracion de soluciones organicas de peracidos carboxilicos
ES455064A1 (es) Nuevo procedimiento para la obtencion del acido (d)-2(6-me- toxi-2-naftil)-propionico.
ES512933A0 (es) Un procedimiento para la produccion de sales magnesicas hidratadas por reaccion entre peroxido de hidrogeno, un anhidrido, una base y agua.
SE7602714L (sv) Sett for rening av ettiksyrahaltig svavelsyra
GB1501997A (en) Process for the purification of decane dicarboxylic acid-(1,10)
BE595884A (fr) Procédé de récupération d'acide sulfurique concentré à partir d'acides résiduaires dilués contenant des sels.
DE68910912T2 (de) Herstellung von Pyridazinon.
AR012346A1 (es) Proceso para la fabricacion de compuestos racemicos, compuestos obtenidos por dicho proceso y compuestos intermediarios
GB949669A (en) Process for the production of optically-active ª -alkyl-substituted phenoxyacetic acids and the alkylamides thereof
SU688426A1 (ru) Способ очистки отработанной серной кислоты от органических примесей
FI872671A (fi) Foerfarande foer retardering av i vatten oloesliga peroxikarboxylsyror.
SE8103635L (sv) Sett att framstella dikamba med hog halt
JPS5248519A (en) Purification method of mercury
FR2304255A7 (fr) Procede de fabrication d'acide terephtalique par oxydation du paraxylene
Fisher et al. 5-Bromo-2, 4-xylic Acid. Nuclear Halogenation with Alkaline Hypohalite Solutions
GB960665A (en) Azidophenylacetic acid resolution
FR2419931A1 (fr) Procede pour la fabrication d'acides cyanocarboxyliques
FR1270297A (fr) Procédé de récupération d'acide sulfurique concentré à partir d'acides résiduaires dilués contenant des sels
CO5031274A1 (es) Procedimiento para la produccion de acido maleico con minima produccion de acido fumarico
SU1690317A1 (ru) Способ получения йодноватой кислоты
JPS5559156A (en) Recovery of organic acid as by-product