ES452508A1 - Quaternary ammonium compounds having pharmacological activity - Google Patents

Quaternary ammonium compounds having pharmacological activity

Info

Publication number
ES452508A1
ES452508A1 ES452508A ES452508A ES452508A1 ES 452508 A1 ES452508 A1 ES 452508A1 ES 452508 A ES452508 A ES 452508A ES 452508 A ES452508 A ES 452508A ES 452508 A1 ES452508 A1 ES 452508A1
Authority
ES
Spain
Prior art keywords
formula
carbon atoms
quaternary ammonium
ammonium compounds
pharmacological activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES452508A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Michigan
Original Assignee
University of Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Michigan filed Critical University of Michigan
Publication of ES452508A1 publication Critical patent/ES452508A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Process for preparing quaternary salts of 1- (trialkylamino) -3-phenylphenoxy-2-propanol, of the formula: ** (see formula) ** Wherein r, r 'and r "are lower alkyl groups having from 1 to 4 carbon atoms inclusive and x" is the anion of a non-toxic pharmaceutically acceptable acid, characterized in that it comprises making a compound of the formula: ** (see formula) ** Wherein r and r 'are alkyl radicals containing from 1 to 4 carbon atoms, with a compound of the general formula: (alkyl) x (III) Wherein the alkyl group contains from 1 to 4 carbon atoms and x is a halide, sulfate or phosphate. (Machine-translation by Google Translate, not legally binding)
ES452508A 1975-10-20 1976-10-19 Quaternary ammonium compounds having pharmacological activity Expired ES452508A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62376775A 1975-10-20 1975-10-20

Publications (1)

Publication Number Publication Date
ES452508A1 true ES452508A1 (en) 1977-11-01

Family

ID=24499333

Family Applications (1)

Application Number Title Priority Date Filing Date
ES452508A Expired ES452508A1 (en) 1975-10-20 1976-10-19 Quaternary ammonium compounds having pharmacological activity

Country Status (17)

Country Link
JP (1) JPS5287146A (en)
AT (1) AT344686B (en)
AU (1) AU1881776A (en)
BE (1) BE847428A (en)
CA (1) CA1076605A (en)
CH (1) CH605635A5 (en)
DE (1) DE2647038A1 (en)
DK (1) DK470076A (en)
ES (1) ES452508A1 (en)
FR (1) FR2328459A1 (en)
GB (1) GB1561718A (en)
IL (1) IL50716A0 (en)
NL (1) NL7611543A (en)
NO (1) NO763555L (en)
NZ (1) NZ182359A (en)
SE (1) SE7611575L (en)
ZA (1) ZA766218B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202144322A (en) * 2020-03-31 2021-12-01 日商納美仕有限公司 Epoxy amine adduct, curing catalyst, resin composition, sealing material, adhesive and cured article

Also Published As

Publication number Publication date
FR2328459A1 (en) 1977-05-20
SE7611575L (en) 1977-04-21
GB1561718A (en) 1980-02-27
ZA766218B (en) 1977-11-30
NO763555L (en) 1977-04-21
NL7611543A (en) 1977-04-22
JPS5287146A (en) 1977-07-20
DK470076A (en) 1977-04-21
IL50716A0 (en) 1976-12-31
CH605635A5 (en) 1978-10-13
AT344686B (en) 1978-08-10
CA1076605A (en) 1980-04-29
DE2647038A1 (en) 1977-04-21
ATA776976A (en) 1977-12-15
AU1881776A (en) 1978-04-27
BE847428A (en) 1977-04-19
NZ182359A (en) 1979-06-08

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