ES452447A1 - Mejoras introducidas en un organo de insercion ocular para tratar el ojo seco de secrecion lacrimal deficiente. - Google Patents
Mejoras introducidas en un organo de insercion ocular para tratar el ojo seco de secrecion lacrimal deficiente.Info
- Publication number
- ES452447A1 ES452447A1 ES452447A ES452447A ES452447A1 ES 452447 A1 ES452447 A1 ES 452447A1 ES 452447 A ES452447 A ES 452447A ES 452447 A ES452447 A ES 452447A ES 452447 A1 ES452447 A1 ES 452447A1
- Authority
- ES
- Spain
- Prior art keywords
- therapeutic agent
- dry eye
- therapeutic system
- treating aqueous
- proportional amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
Abstract
Mejoras introducidas en un órgano de inserción ocular para tratar el ojo seco de secreción lacrimal deficiente, comprendiendo dicho órgano de inserción un agente terapéutico confinado dentro de un cuerpo de polímero de tamaño y forma idóneos para ser introducido y retenido en el fondo de la cavidad ocular y que cuando se coloca en el ojo libera el agente terapéutico en forma continua durante un periodo de tiempo prolongado y en una cantidad proporcional controlada, caracterizadas dichas mejoras por el hecho de que el agente terapéutico es una disolución biológicamente compatible, y la cantidad proporcional es suficiente para inducir un flujo acuoso endógeno significativo a la película lagrimal.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/625,918 US3991759A (en) | 1975-10-28 | 1975-10-28 | Method and therapeutic system for treating aqueous deficient dry eye |
Publications (1)
Publication Number | Publication Date |
---|---|
ES452447A1 true ES452447A1 (es) | 1978-02-16 |
Family
ID=24508173
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES452447A Expired ES452447A1 (es) | 1975-10-28 | 1976-10-15 | Mejoras introducidas en un organo de insercion ocular para tratar el ojo seco de secrecion lacrimal deficiente. |
Country Status (18)
Country | Link |
---|---|
US (1) | US3991759A (es) |
JP (1) | JPS5255291A (es) |
AR (1) | AR213293A1 (es) |
AT (1) | AT353412B (es) |
AU (1) | AU502717B2 (es) |
BE (1) | BE847686A (es) |
CA (1) | CA1070614A (es) |
DE (1) | DE2648737A1 (es) |
DK (1) | DK487876A (es) |
ES (1) | ES452447A1 (es) |
FR (1) | FR2329261A1 (es) |
GB (1) | GB1526476A (es) |
IE (1) | IE44351B1 (es) |
IL (1) | IL50651A (es) |
IT (1) | IT1070272B (es) |
NL (1) | NL7611911A (es) |
SE (1) | SE7611944L (es) |
ZA (1) | ZA765799B (es) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4177256A (en) * | 1973-04-25 | 1979-12-04 | Alza Corporation | Osmotic bursting drug delivery device |
US4207890A (en) * | 1977-01-04 | 1980-06-17 | Mcneilab, Inc. | Drug-dispensing device and method |
US4190642A (en) * | 1978-04-17 | 1980-02-26 | Alza Corporation | Ocular therapeutic system for dispensing a medication formulation |
US4287175A (en) * | 1978-06-22 | 1981-09-01 | Merck & Co., Inc. | Contact lens wetting agents |
US4868154A (en) * | 1986-02-19 | 1989-09-19 | Eye Research Institute Of Retina Foundation | Stimulation of tear secretion with melanocyte stimulating hormones |
US4883658A (en) * | 1986-04-28 | 1989-11-28 | Holly Frank J | Ophthalmic solution for treatment of dry-eye syndrome |
US4744980A (en) * | 1986-04-28 | 1988-05-17 | Holly Frank J | Ophthalmic solution for treatment of dry eye syndrome |
US5660851A (en) * | 1989-12-26 | 1997-08-26 | Yissum Research Development Company Of The Hebrew Univ. Of Jerusalem | Ocular inserts |
US5290572A (en) * | 1992-08-06 | 1994-03-01 | Deo Corporation | Opthalmic composition for treating dry eye |
US5830508A (en) * | 1992-08-06 | 1998-11-03 | Deo Corporation | Composition for treating dry eye |
DE19508029C2 (de) * | 1995-03-07 | 1997-10-09 | Richard Prof Dr Sueverkruep | Darreichungsform zur äußerlichen Applikation von ophthalmischen Arzneistoffen und Verfahren zur Herstellung derselben |
US5696166A (en) * | 1995-10-31 | 1997-12-09 | Yanni; John M. | Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders |
ZA989513B (en) | 1997-10-21 | 1999-04-21 | Alcon Lab Inc | Compositions containing histamine H2 agonists and methods of use in treating dry eye |
AU2183900A (en) | 1998-12-24 | 2000-07-31 | Alcon Laboratories, Inc. | Ep4 receptor agonists for treatment of dry eye |
WO2000038690A2 (en) | 1998-12-24 | 2000-07-06 | Alcon Laboratories, Inc. | Prostaglandin e agonists for treatment of dry eye |
TR200201250T2 (tr) | 1999-11-09 | 2002-09-23 | Alcon, Inc | Hidroksieikosatetraenoat tuzları, bileşimleri ve bunların göz kuruması bozukluklarının iyileştirilmesinde kullanım yöntemleri. |
ATE258791T1 (de) | 1999-11-09 | 2004-02-15 | Alcon Inc | Lipoxin-a4 und deren analoge zur behandlung von trockenen augen |
US6458854B2 (en) | 1999-11-09 | 2002-10-01 | Alcon Universal Ltd. | Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use |
CN1387504A (zh) | 1999-11-09 | 2002-12-25 | 爱尔康公司 | ω-链改性的15-羟基二十碳四烯酸衍生物和它们用于治疗干眼病的方法 |
US6320062B1 (en) | 1999-11-09 | 2001-11-20 | Alcon Universal Ltd. | 15-hydroxyeicosatetraenoic acid analogs with enhanced metabolic stability and methods of their use in treating dry eye disorders |
US6803385B2 (en) | 1999-11-09 | 2004-10-12 | Alcon, Inc. | Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders |
US6353032B1 (en) | 1999-11-09 | 2002-03-05 | Alcon Universal Ltd. | Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use |
DE60020591T2 (de) | 1999-11-09 | 2005-11-10 | Alcon Inc. | Benzenoidderivate von 15-hydroxyeicosatetraesäure und verfahren zur verwendung zur behandlung des trockenen auges |
PL355998A1 (en) | 1999-11-09 | 2004-05-31 | Alcon Inc. | Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders |
AU776146B2 (en) | 1999-11-09 | 2004-08-26 | Alcon Inc. | 3-heteroatom substituted and two carbon homologs of 15-HETE and methods of use |
MXPA02004700A (es) | 1999-11-09 | 2004-09-10 | Alcon Inc | Compuestos relacionados con acido 15-hidroxieicosatetraenoico y metodos de uso. |
US6552084B2 (en) | 1999-11-09 | 2003-04-22 | Alcon Universal Ltd. | Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders |
TR200201249T2 (tr) | 1999-11-09 | 2002-09-23 | Alcon, Inc. | 15-hidroksieikosatetraenoik asitin heteroatomun araya girdiği analogları ve bunların kullanım yöntemleri. |
AU1101301A (en) | 1999-11-09 | 2001-06-06 | Alcon Universal Limited | 2,2-difluoro 15-hydroxyeicosatetraenoic acid analogs and methods of use |
AU2603301A (en) | 1999-12-22 | 2001-07-03 | Alcon Universal Limited | 6-keto prostaglandin F1alpha and analogs for treating dry eye |
AR031135A1 (es) | 2000-10-10 | 2003-09-10 | Upjohn Co | Composiciones de antibiotico topico para el tratamiento de infecciones oculares |
US6872382B1 (en) | 2001-05-21 | 2005-03-29 | Alcon, Inc. | Use of selective PDE IV inhibitors to treat dry eye disorders |
CN1509462A (zh) | 2001-05-21 | 2004-06-30 | NF-κB抑制剂在治疗干眼疾病中的用途 | |
PT1392355E (pt) | 2001-05-21 | 2007-03-30 | Alcon Inc | Utilização de inibidores do proteassoma para tratar distúrbios associados à secura ocular |
EP1392322A1 (en) * | 2001-05-21 | 2004-03-03 | Alcon, Inc. | Method of treating dry eye disorders |
US7112588B2 (en) * | 2001-05-21 | 2006-09-26 | Alcon, Inc. | Use of proteasome inhibitors to treat dry eye disorders |
US6645994B1 (en) | 2001-06-01 | 2003-11-11 | Alcon, Inc. | Method of treating dry eye disorders |
US6750250B1 (en) | 2001-07-12 | 2004-06-15 | Alcon, Inc. | 11,12-oxidoarachidonic acid derivatives and methods of their use in treating dry eye disorders |
AU2003303623A1 (en) * | 2002-12-20 | 2004-07-29 | Alcon, Inc. | Treatment of dry eye by restoring 15-lipoxygenase activity to ocular surface cells |
NZ552481A (en) * | 2004-07-01 | 2008-12-24 | Schepens Eye Res | Compositions and methods for treating eye disorders and conditions |
US20090142292A1 (en) * | 2007-12-03 | 2009-06-04 | Blackwell Richard I | Method For The Mitigation of Symptoms of Dry Eye |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3896819A (en) * | 1969-04-01 | 1975-07-29 | Alejandro Zaffaroni | IUD having a replenishing drug reservoir |
US3664340A (en) * | 1969-10-17 | 1972-05-23 | Loran B Morgan | Scleral lens with attached tube |
US3828777A (en) * | 1971-11-08 | 1974-08-13 | Alza Corp | Microporous ocular device |
US3832458A (en) * | 1971-12-06 | 1974-08-27 | River C Foundation | Hydrophilic silicone composition and method |
US3818909A (en) * | 1972-10-25 | 1974-06-25 | F Bratton | Eye treatment application devices |
US3811444A (en) * | 1972-12-27 | 1974-05-21 | Alza Corp | Bioerodible ocular device |
US3917119A (en) * | 1974-11-01 | 1975-11-04 | Bel Art Prod Inc | Squeeze type device for dispensing liquid medicaments or the like to a bodily organ |
-
1975
- 1975-10-28 US US05/625,918 patent/US3991759A/en not_active Expired - Lifetime
-
1976
- 1976-09-22 IE IE2092/76A patent/IE44351B1/en unknown
- 1976-09-22 GB GB39320/76A patent/GB1526476A/en not_active Expired
- 1976-09-28 ZA ZA765799A patent/ZA765799B/xx unknown
- 1976-10-10 IL IL50651A patent/IL50651A/xx unknown
- 1976-10-12 AR AR265061A patent/AR213293A1/es active
- 1976-10-15 ES ES452447A patent/ES452447A1/es not_active Expired
- 1976-10-21 IT IT69536/76A patent/IT1070272B/it active
- 1976-10-26 FR FR7632190A patent/FR2329261A1/fr active Granted
- 1976-10-26 AU AU18999/76A patent/AU502717B2/en not_active Expired
- 1976-10-27 DE DE19762648737 patent/DE2648737A1/de not_active Withdrawn
- 1976-10-27 BE BE171834A patent/BE847686A/xx unknown
- 1976-10-27 CA CA264,278A patent/CA1070614A/en not_active Expired
- 1976-10-27 JP JP51128407A patent/JPS5255291A/ja active Pending
- 1976-10-27 SE SE7611944A patent/SE7611944L/ not_active Application Discontinuation
- 1976-10-27 NL NL7611911A patent/NL7611911A/xx not_active Application Discontinuation
- 1976-10-28 DK DK487876A patent/DK487876A/da unknown
- 1976-10-28 AT AT801676A patent/AT353412B/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU1899976A (en) | 1978-05-04 |
GB1526476A (en) | 1978-09-27 |
ZA765799B (en) | 1977-09-28 |
FR2329261A1 (fr) | 1977-05-27 |
BE847686A (fr) | 1977-02-14 |
AT353412B (de) | 1979-11-12 |
FR2329261B1 (es) | 1978-11-03 |
AR213293A1 (es) | 1979-01-15 |
NL7611911A (nl) | 1977-05-02 |
JPS5255291A (en) | 1977-05-06 |
SE7611944L (sv) | 1977-04-29 |
IL50651A0 (en) | 1976-12-31 |
IT1070272B (it) | 1985-03-29 |
ATA801676A (de) | 1979-04-15 |
CA1070614A (en) | 1980-01-29 |
IE44351B1 (en) | 1981-11-04 |
IL50651A (en) | 1979-12-30 |
IE44351L (en) | 1977-04-28 |
US3991759A (en) | 1976-11-16 |
DE2648737A1 (de) | 1977-05-05 |
AU502717B2 (en) | 1979-08-02 |
DK487876A (da) | 1977-04-29 |
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