ES450364A1 - Oral compositions containing trifluoromethyl phenyl bis-biguanides as antiplaque agents - Google Patents
Oral compositions containing trifluoromethyl phenyl bis-biguanides as antiplaque agentsInfo
- Publication number
- ES450364A1 ES450364A1 ES450364A ES450364A ES450364A1 ES 450364 A1 ES450364 A1 ES 450364A1 ES 450364 A ES450364 A ES 450364A ES 450364 A ES450364 A ES 450364A ES 450364 A1 ES450364 A1 ES 450364A1
- Authority
- ES
- Spain
- Prior art keywords
- atoms
- biguanides
- compositions containing
- oral compositions
- trifluoromethyl phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000002882 anti-plaque Effects 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- -1 trifluoromethyl phenyl bis-biguanides Chemical class 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229940112822 chewing gum Drugs 0.000 abstract 1
- 235000015218 chewing gum Nutrition 0.000 abstract 1
- 239000012459 cleaning agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 210000000214 mouth Anatomy 0.000 abstract 1
- 239000002324 mouth wash Substances 0.000 abstract 1
- 229940051866 mouthwash Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/43—Guanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/69—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing fluorine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/24—Y being a hetero atom
- C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
- C07C279/265—X and Y being nitrogen atoms, i.e. biguanides containing two or more biguanide groups
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Cosmetics (AREA)
- Confectionery (AREA)
Abstract
A composition for oral and/or dental care, e.g. in the form of a tooth cleaning agent or mouthwash or chewing gum, contains a vehicle for use in the oral cavity and antiplaque agent of the formula (1) < IMAGE > in which n is a number from 1 up to and including 4, X and X' are each an alkylene radical which contains 1-3 C atoms, z and z' are zero or one, R and R' are each hydrogen atoms, alkyl radicals with 1-12 C atoms or aralkyl radicals with 7-12 C atoms, and R2 and R2' are each hydrogen atoms or alkyl radicals with 1-2 C atoms, or a pharmacologically acceptable salt of a compound of the formula (1).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60124475A | 1975-08-01 | 1975-08-01 | |
| US05/669,930 US4067962A (en) | 1975-08-01 | 1976-03-24 | Oral compositions containing trifluoromethyl phenyl bis-biguanides as antiplaque agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES450364A1 true ES450364A1 (en) | 1977-08-16 |
Family
ID=27083824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES450364A Expired ES450364A1 (en) | 1975-08-01 | 1976-07-31 | Oral compositions containing trifluoromethyl phenyl bis-biguanides as antiplaque agents |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS5254036A (en) |
| AT (1) | AT348682B (en) |
| CH (1) | CH621938A5 (en) |
| DE (1) | DE2633651A1 (en) |
| DK (1) | DK343676A (en) |
| ES (1) | ES450364A1 (en) |
| FR (1) | FR2319336A1 (en) |
| GB (1) | GB1549074A (en) |
| IE (1) | IE43411B1 (en) |
| IT (1) | IT1062647B (en) |
| LU (1) | LU75517A1 (en) |
| NL (1) | NL7608480A (en) |
| SE (2) | SE429923B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2262283B (en) * | 1991-12-12 | 1996-01-17 | Mitsubishi Materials Corp | Biguanide disinfectants |
| US8287843B2 (en) | 2003-06-23 | 2012-10-16 | Colgate-Palmolive Company | Antiplaque oral care compositions |
| WO2005000253A1 (en) | 2003-06-23 | 2005-01-06 | Colgate-Palmolive Company | Stable dentifrice compositions |
-
1976
- 1976-07-27 DE DE19762633651 patent/DE2633651A1/en not_active Withdrawn
- 1976-07-29 SE SE7608566A patent/SE429923B/en unknown
- 1976-07-30 FR FR7623368A patent/FR2319336A1/en active Granted
- 1976-07-30 IE IE1699/76A patent/IE43411B1/en unknown
- 1976-07-30 IT IT50698/76A patent/IT1062647B/en active
- 1976-07-30 DK DK343676A patent/DK343676A/en not_active Application Discontinuation
- 1976-07-30 AT AT566776A patent/AT348682B/en not_active IP Right Cessation
- 1976-07-30 CH CH974676A patent/CH621938A5/en not_active IP Right Cessation
- 1976-07-30 NL NL7608480A patent/NL7608480A/en not_active Application Discontinuation
- 1976-07-30 GB GB31865/76A patent/GB1549074A/en not_active Expired
- 1976-07-30 JP JP51090392A patent/JPS5254036A/en active Pending
- 1976-07-31 ES ES450364A patent/ES450364A1/en not_active Expired
- 1976-08-02 LU LU75517A patent/LU75517A1/xx unknown
-
1980
- 1980-12-11 SE SE8008721A patent/SE8008721L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IE43411B1 (en) | 1981-02-25 |
| NL7608480A (en) | 1977-02-03 |
| JPS5254036A (en) | 1977-05-02 |
| GB1549074A (en) | 1979-08-01 |
| DK343676A (en) | 1977-02-02 |
| FR2319336A1 (en) | 1977-02-25 |
| IE43411L (en) | 1977-02-01 |
| FR2319336B1 (en) | 1979-07-13 |
| SE8008721L (en) | 1980-12-11 |
| LU75517A1 (en) | 1977-04-20 |
| CH621938A5 (en) | 1981-03-13 |
| AT348682B (en) | 1979-02-26 |
| SE429923B (en) | 1983-10-10 |
| IT1062647B (en) | 1984-10-20 |
| SE7608566L (en) | 1977-02-02 |
| DE2633651A1 (en) | 1977-02-17 |
| ATA566776A (en) | 1978-07-15 |
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