ES449747A1 - Process for obtaining crystalline aesein - Google Patents

Process for obtaining crystalline aesein

Info

Publication number
ES449747A1
ES449747A1 ES449747A ES449747A ES449747A1 ES 449747 A1 ES449747 A1 ES 449747A1 ES 449747 A ES449747 A ES 449747A ES 449747 A ES449747 A ES 449747A ES 449747 A1 ES449747 A1 ES 449747A1
Authority
ES
Spain
Prior art keywords
seeds
crystalline
water
cation exchanger
eluate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES449747A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Madaus Holding GmbH
Original Assignee
Dr Madaus GmbH and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Madaus GmbH and Co filed Critical Dr Madaus GmbH and Co
Publication of ES449747A1 publication Critical patent/ES449747A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/256Polyterpene radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Procedure for the obtaining of crystalline escin from the seeds of aesculus hippocastanum, characterized by extracting shredded seeds of aesculus hippocastanum with organic solvents miscible with water, mainly alcohols, putting the extraction liquids obtained in contact with a cation exchanger in h form, the resulting eluate is concentrated by distillation, after removing the cation exchanger, treating the eluate with water, separating by filtration or centrifugation the crystalline precipitate originated and eventually converting the obtained scinic acid, with a pharmacologically compatible base, into the corresponding salt. (Machine-translation by Google Translate, not legally binding)
ES449747A 1975-07-11 1976-07-10 Process for obtaining crystalline aesein Expired ES449747A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2530941A DE2530941C2 (en) 1975-07-11 1975-07-11 Process for the production of crystalline aescin and for the production of certain aescin salts as well as triethanolammonium aescinate and medicaments containing this salt

Publications (1)

Publication Number Publication Date
ES449747A1 true ES449747A1 (en) 1977-08-16

Family

ID=5951217

Family Applications (1)

Application Number Title Priority Date Filing Date
ES449747A Expired ES449747A1 (en) 1975-07-11 1976-07-10 Process for obtaining crystalline aesein

Country Status (21)

Country Link
JP (1) JPS5234913A (en)
AR (1) AR210498A1 (en)
AU (1) AU510202B2 (en)
BE (1) BE844052A (en)
BG (1) BG27378A3 (en)
CA (1) CA1049497A (en)
CS (1) CS193077B2 (en)
DE (1) DE2530941C2 (en)
ES (1) ES449747A1 (en)
FI (1) FI63418C (en)
FR (1) FR2316962A1 (en)
GB (1) GB1551387A (en)
HK (1) HK33781A (en)
HU (1) HU175394B (en)
PH (1) PH13088A (en)
PL (1) PL99027B1 (en)
PT (1) PT65301B (en)
RO (1) RO71026A (en)
SU (1) SU786856A3 (en)
YU (1) YU39215B (en)
ZA (1) ZA764064B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60214046T2 (en) * 2002-03-25 2007-02-15 Council Of Scientific And Industrial Research A SIMPLE METHOD FOR OBTAINING BETA AESCINE FROM INDIAN ROCK CHESTNUTS (AESCULUS INDICA)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1095989B (en) * 1959-03-11 1960-12-29 Madaus & Co Dr Process for obtaining a crystallized acidic saponin from the seeds of the horse chestnut
FR1267224A (en) * 1960-06-07 1961-07-21 Madaus & Co Dr Process for the preparation of crystallized acid saponin from horse chestnuts
DE1667884B2 (en) * 1968-01-20 1976-09-30 Knoll Ag, Chemische Fabriken, 6700 Ludwigshafen PROCESS FOR THE EXTRACTION OF PURE AESCINE
DE2118916A1 (en) * 1971-04-19 1972-11-09 Schwabe, Willmar, Dr., 7500 Karlsruhe-Durlach Water-soluble acid saponin mixts prodn - by extraction of horse-chestnuts and complex formation with (alkyl)benzene
YU37063B (en) * 1971-12-06 1984-08-31 Lek Tovarna Farmacevtskih Process for preparing x-ray amorphous water-sulubleascin

Also Published As

Publication number Publication date
JPS5539560B2 (en) 1980-10-13
HK33781A (en) 1981-07-24
AU1573076A (en) 1978-01-12
PT65301A (en) 1976-07-01
FR2316962B1 (en) 1979-03-02
DE2530941C2 (en) 1991-10-10
JPS5234913A (en) 1977-03-17
FI63418B (en) 1983-02-28
RO71026A (en) 1981-09-24
YU39215B (en) 1984-08-31
FR2316962A1 (en) 1977-02-04
PL99027B1 (en) 1978-06-30
CA1049497A (en) 1979-02-27
DE2530941A1 (en) 1977-01-27
HU175394B (en) 1980-07-28
BG27378A3 (en) 1979-10-12
CS193077B2 (en) 1979-09-17
PH13088A (en) 1979-11-23
GB1551387A (en) 1979-08-30
YU166976A (en) 1982-08-31
PT65301B (en) 1977-12-13
AR210498A1 (en) 1977-08-15
FI761957A (en) 1977-01-12
ZA764064B (en) 1977-07-27
FI63418C (en) 1983-06-10
BE844052A (en) 1977-01-12
SU786856A3 (en) 1980-12-07
AU510202B2 (en) 1980-06-12

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