ES448213A1 - Procedure for the preparation of substitute unidazolines. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of substitute unidazolines. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES448213A1
ES448213A1 ES76448213A ES448213A ES448213A1 ES 448213 A1 ES448213 A1 ES 448213A1 ES 76448213 A ES76448213 A ES 76448213A ES 448213 A ES448213 A ES 448213A ES 448213 A1 ES448213 A1 ES 448213A1
Authority
ES
Spain
Prior art keywords
acid addition
addition salt
translation
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES76448213A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scherico Ltd
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/582,313 external-priority patent/US3992403A/en
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of ES448213A1 publication Critical patent/ES448213A1/en
Expired legal-status Critical Current

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Abstract

Procedure for the preparation of imidazolines substituted in position 2 of the general formula I **(See formula)** and its acid addition salts, in which Q represents either a cyclopropylene group or a mono, di or trisubstituted ethylene group with the lower alcohol or cycloalcohyl substituent (s) being, and R represents the group **(See formula)** or Q represents methylene and R represents the grouping **(See formula)** whereby in the formulas R1 represents hydrogen, lower alcohol or cycloalkoxy, X and Y represent hydrogen or fluorine and n is an integer from 1 to 3; characterized in that a compound of the general formula VIII R-Q-Z (VIII) wherein R and Q are as defined above and 2 represents a carboxy group or one of its reactive derivatives, it is reacted with ethylenediamine or one of its reactive derivatives, and because the thus obtained imidazoline compound is isolated in free form or in the form of an acid addition salt and because if desired, the free base thus obtained is transformed into an acid addition salt, and respectively the acid addition salt thus obtained is transformed into the free base or another acid addition salt. (Machine-translation by Google Translate, not legally binding)
ES76448213A 1975-05-30 1976-05-25 Procedure for the preparation of substitute unidazolines. (Machine-translation by Google Translate, not legally binding) Expired ES448213A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58231275A 1975-05-30 1975-05-30
US05/582,313 US3992403A (en) 1975-05-30 1975-05-30 2-Imidazolines and their use as hypoglycemic agents
CH630876 1976-05-18

Publications (1)

Publication Number Publication Date
ES448213A1 true ES448213A1 (en) 1977-11-01

Family

ID=27175463

Family Applications (1)

Application Number Title Priority Date Filing Date
ES76448213A Expired ES448213A1 (en) 1975-05-30 1976-05-25 Procedure for the preparation of substitute unidazolines. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES448213A1 (en)

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