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Labaz SA
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Labaz SA
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Priority to ES399253ApriorityCriticalpatent/ES399253A1/en
Publication of ES399253A1publicationCriticalpatent/ES399253A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Process for the preparation of imidazoline derivatives, of the general formula: ** (see formula) ** And the pharmaceutically acceptable acid addition salts thereof, in which formula r represents a straight or branched chain alkyl group containing from 1 to 4 carbon atoms; characterized in that ethylenediamine is reacted, in a lower alcohol, with an acid addition salt of a lower alkyl (2-alkylbenzo [b] furan-3-yl) -iminoacetate, of the general formula: ** (see formula) ** Wherein r'represents a lower alkyl group containing from 1 to 4 carbon atoms, x represents the anion of a strong acid and r is defined as above, to form the corresponding acid addition salt of the required compound of general formula i, which can be done; then reacting with a base to obtain the compound of formula i in the form of the free base, which, if desired, can be reacted with an organic or inorganic acid to form a different pharmaceutically acceptable acid addition salt. (Machine-translation by Google Translate, not legally binding)
ES399253A1972-01-271972-01-27Procedure for the preparation of imidazoline derivatives. (Machine-translation by Google Translate, not legally binding)
ExpiredES399253A1
(en)