ES445762A1 - Procedimiento para preparar 2-oxo-1-pirrolidinilacetamida. - Google Patents
Procedimiento para preparar 2-oxo-1-pirrolidinilacetamida.Info
- Publication number
- ES445762A1 ES445762A1 ES445762A ES445762A ES445762A1 ES 445762 A1 ES445762 A1 ES 445762A1 ES 445762 A ES445762 A ES 445762A ES 445762 A ES445762 A ES 445762A ES 445762 A1 ES445762 A1 ES 445762A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- acetamide
- oxo
- production
- pharmaceutically useful
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 title 2
- NLKNQRATVPKPDG-UHFFFAOYSA-M potassium iodide Chemical compound [K+].[I-] NLKNQRATVPKPDG-UHFFFAOYSA-M 0.000 abstract 3
- WKNMKGVLOWGGOU-UHFFFAOYSA-N 2-aminoacetamide;hydron;chloride Chemical compound Cl.NCC(N)=O WKNMKGVLOWGGOU-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- -1 ethyl 4-chlorobutyric acid ester Chemical class 0.000 abstract 1
- SIXPSGNZQPKXTG-UHFFFAOYSA-N n-(2-oxopyrrolidin-1-yl)acetamide Chemical compound CC(=O)NN1CCCC1=O SIXPSGNZQPKXTG-UHFFFAOYSA-N 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI750944A FI51098C (fi) | 1975-03-27 | 1975-03-27 | Menetelmä terapeuttisesti arvokkaan 2-okso-1-pyrrolidinyyliasetamidin valmistamiseksi. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES445762A1 true ES445762A1 (es) | 1977-06-01 |
Family
ID=8509097
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES445762A Expired ES445762A1 (es) | 1975-03-27 | 1976-03-04 | Procedimiento para preparar 2-oxo-1-pirrolidinilacetamida. |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS51113867A (de) |
| AT (1) | AT347447B (de) |
| CA (1) | CA1059137A (de) |
| CH (1) | CH599151A5 (de) |
| ES (1) | ES445762A1 (de) |
| FI (1) | FI51098C (de) |
| NL (1) | NL7602263A (de) |
| PT (1) | PT64933B (de) |
| SU (1) | SU655304A3 (de) |
| YU (1) | YU45476A (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT391134B (de) * | 1979-03-22 | 1990-08-27 | Continental Pharma | Verfahren zum herstellen von neuen glycinamidderivaten, deren additionssalzen und deren optischen isomeren |
| IT1206699B (it) * | 1984-02-27 | 1989-04-27 | Isf Spa | Procedimento per preparare derivati di pirrolidone. |
| DE3683728D1 (de) | 1985-07-26 | 1992-03-12 | Denki Kagaku Kogyo Kk | Verfahren zur herstellung von oxiracetam. |
| CH680293A5 (de) * | 1990-06-26 | 1992-07-31 | Lonza Ag | |
| JP2969616B2 (ja) * | 1994-11-24 | 1999-11-02 | 田辺製薬株式会社 | ４−メルカプトピロリジン化合物の製法 |
| PL389364A1 (pl) | 2009-10-23 | 2011-04-26 | Uniwersytet Jagielloński | Nowe zastosowanie pochodnych 2-pirolidonu |
| RU2629117C1 (ru) * | 2016-06-14 | 2017-08-24 | Сизов Владимир Владимирович | Способ получения 4-замещенного 2-[2-оксо-1-пирролидинил] ацетамида |
-
1975
- 1975-03-27 FI FI750944A patent/FI51098C/fi not_active IP Right Cessation
-
1976
- 1976-02-21 JP JP1838876A patent/JPS51113867A/ja active Granted
- 1976-02-24 YU YU45476A patent/YU45476A/xx unknown
- 1976-03-04 ES ES445762A patent/ES445762A1/es not_active Expired
- 1976-03-04 NL NL7602263A patent/NL7602263A/xx not_active Application Discontinuation
- 1976-03-05 CA CA247,190A patent/CA1059137A/en not_active Expired
- 1976-03-22 PT PT6493376A patent/PT64933B/pt unknown
- 1976-03-23 CH CH361876A patent/CH599151A5/de not_active IP Right Cessation
- 1976-03-26 AT AT223576A patent/AT347447B/de not_active IP Right Cessation
-
1977
- 1977-12-05 SU SU772549949A patent/SU655304A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| PT64933B (en) | 1977-08-24 |
| FI51098C (fi) | 1976-10-11 |
| JPS5652017B2 (de) | 1981-12-09 |
| NL7602263A (nl) | 1976-09-29 |
| PT64933A (en) | 1976-04-01 |
| YU45476A (en) | 1982-05-31 |
| FI51098B (de) | 1976-06-30 |
| AT347447B (de) | 1978-12-27 |
| ATA223576A (de) | 1978-05-15 |
| CA1059137A (en) | 1979-07-24 |
| SU655304A3 (ru) | 1979-03-30 |
| CH599151A5 (en) | 1978-05-12 |
| JPS51113867A (en) | 1976-10-07 |
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