ES444644A1 - Process for the preparation of thieno-pyridine derivatives - Google Patents

Process for the preparation of thieno-pyridine derivatives

Info

Publication number
ES444644A1
ES444644A1 ES444644A ES444644A ES444644A1 ES 444644 A1 ES444644 A1 ES 444644A1 ES 444644 A ES444644 A ES 444644A ES 444644 A ES444644 A ES 444644A ES 444644 A1 ES444644 A1 ES 444644A1
Authority
ES
Spain
Prior art keywords
formula
aryl
halogen
derivative
see
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES444644A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parcor SARL
Original Assignee
Parcor SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26218725&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES444644(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR7503968A external-priority patent/FR2300090A1/en
Priority claimed from FR7523786A external-priority patent/FR2319642A2/en
Application filed by Parcor SARL filed Critical Parcor SARL
Publication of ES444644A1 publication Critical patent/ES444644A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)

Abstract

A method of preparing thienopyridine derivatives of the formula: **(See formula)** in which R1 represents an optionally substituted alcoholic, aryl or aralcohyl radical, and R2 and R3 represent hydrogen or a lower alcoholic, aryl or heterocyclic radical, characterized in that (a) a derivative of formula is reacted: **(See formula)** in which R2 and R3 are as defined for formula (I) and X represents hydrogen, or an alkali metal, or a MgY radical in which Y represents a halogen, with a halogen-sulfonated derivative of formula Hal- SO2-R4 (III) in which Hal represents a halogen and represents an optionally substituted alcoholic, aryl or aralcohyl group, thus obtaining a compound of formula: **(See formula)** that (b) is then reacted with an amine of formula R1-NH2 (V), wherein R1 is as defined for formula (I), to obtain a compound of formula: **(See formula)** which (c) is then cyclized by means of formaldehyde to give the derivative of formula (I). (Machine-translation by Google Translate, not legally binding)
ES444644A 1975-02-07 1976-01-27 Process for the preparation of thieno-pyridine derivatives Expired ES444644A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7503968A FR2300090A1 (en) 1975-02-07 1975-02-07 Tetrahydro-thieno-pyridine derivs. prepn. - by cyclizing 2-(2-aminoethyl)thiophenes with formaldehyde (BE060876)
FR7523786A FR2319642A2 (en) 1975-07-30 1975-07-30 Tetrahydro-thieno-pyridine derivs. prepn. - by cyclizing 2-(2-aminoethyl)thiophenes with formaldehyde (BE060876)

Publications (1)

Publication Number Publication Date
ES444644A1 true ES444644A1 (en) 1977-05-16

Family

ID=26218725

Family Applications (1)

Application Number Title Priority Date Filing Date
ES444644A Expired ES444644A1 (en) 1975-02-07 1976-01-27 Process for the preparation of thieno-pyridine derivatives

Country Status (23)

Country Link
JP (1) JPS5931513B2 (en)
AR (1) AR211532A1 (en)
AT (1) AT345831B (en)
AU (1) AU496832B2 (en)
CA (1) CA1071630A (en)
CH (1) CH599217A5 (en)
DD (1) DD122977A5 (en)
DE (1) DE2604248C2 (en)
DK (1) DK136653B (en)
ES (1) ES444644A1 (en)
GB (1) GB1477990A (en)
GR (1) GR58595B (en)
HU (1) HU174050B (en)
IL (1) IL48926A (en)
MX (1) MX3207E (en)
NL (1) NL181432C (en)
PH (1) PH14038A (en)
PL (1) PL97671B1 (en)
PT (1) PT64782B (en)
RO (1) RO68148A (en)
SE (1) SE421621B (en)
SU (1) SU640665A3 (en)
YU (1) YU39610B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63137019U (en) * 1987-02-27 1988-09-08
FR2800070B1 (en) * 1999-10-22 2003-08-15 Sanofi Synthelabo PROCESS FOR THE PREPARATION OF A THIOPHENE DERIVATIVE

Also Published As

Publication number Publication date
YU26776A (en) 1982-05-31
AT345831B (en) 1978-10-10
PL97671B1 (en) 1978-03-30
GR58595B (en) 1977-11-10
DK46376A (en) 1976-08-08
DK136653B (en) 1977-11-07
RO68148A (en) 1981-05-30
PT64782B (en) 1977-07-07
NL7600998A (en) 1976-08-10
ATA75976A (en) 1978-02-15
CA1071630A (en) 1980-02-12
MX3207E (en) 1980-08-07
DD122977A5 (en) 1976-11-12
SE421621B (en) 1982-01-18
IL48926A0 (en) 1976-03-31
NL181432B (en) 1987-03-16
AU1091176A (en) 1977-08-11
DK136653C (en) 1978-04-10
AR211532A1 (en) 1978-01-30
IL48926A (en) 1978-07-31
AU496832B2 (en) 1978-11-02
CH599217A5 (en) 1978-05-12
PH14038A (en) 1980-12-12
YU39610B (en) 1985-03-20
HU174050B (en) 1979-10-28
GB1477990A (en) 1977-06-29
PT64782A (en) 1976-03-01
JPS51101996A (en) 1976-09-08
DE2604248A1 (en) 1976-08-19
DE2604248C2 (en) 1986-02-13
NL181432C (en) 1987-08-17
SE7601247L (en) 1976-08-09
SU640665A3 (en) 1978-12-30
JPS5931513B2 (en) 1984-08-02

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