ES444611A1 - Procedure for the preparation of aminopropanos replaced in position 1 with ariloxi and in position 3 in n. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of aminopropanos replaced in position 1 with ariloxi and in position 3 in n. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES444611A1
ES444611A1 ES444611A ES444611A ES444611A1 ES 444611 A1 ES444611 A1 ES 444611A1 ES 444611 A ES444611 A ES 444611A ES 444611 A ES444611 A ES 444611A ES 444611 A1 ES444611 A1 ES 444611A1
Authority
ES
Spain
Prior art keywords
aminopropanos
ariloxi
translation
replaced
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES444611A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES444611A1 publication Critical patent/ES444611A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1854—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1-Aryloxy-3-N-aminopropanes substituted on the nitrogen atom, of the formula I < IMAGE > in which the symbols R1, R2, R3, R4 and R5 have the meaning given in Patent Claim 1, are prepared by reacting an appropriately substituted phenol with an azcetidinol of the formula < IMAGE > The process products are distinguished by a beta -adrenolytic action and can be employed, for example, for the treatment or prophylaxis of disorders of the coronary vessels and for the treatment of cardiac arrhythmias, in particular of tachycardias, in human medicine. The hypotensive properties of the compounds are also of therapeutic interest.
ES444611A 1975-01-27 1976-01-26 Procedure for the preparation of aminopropanos replaced in position 1 with ariloxi and in position 3 in n. (Machine-translation by Google Translate, not legally binding) Expired ES444611A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752503222 DE2503222A1 (en) 1975-01-27 1975-01-27 PROCESS FOR THE PREPARATION OF 1-ARYL-OXY-3-N-SUBSTITUTED AMINOPROPAN DERIVATIVES

Publications (1)

Publication Number Publication Date
ES444611A1 true ES444611A1 (en) 1977-05-01

Family

ID=5937398

Family Applications (1)

Application Number Title Priority Date Filing Date
ES444611A Expired ES444611A1 (en) 1975-01-27 1976-01-26 Procedure for the preparation of aminopropanos replaced in position 1 with ariloxi and in position 3 in n. (Machine-translation by Google Translate, not legally binding)

Country Status (11)

Country Link
JP (1) JPS51125334A (en)
AT (1) AT340389B (en)
CH (1) CH623024A5 (en)
DE (1) DE2503222A1 (en)
DK (1) DK29376A (en)
ES (1) ES444611A1 (en)
FI (1) FI753667A (en)
GR (1) GR59280B (en)
LU (1) LU74246A1 (en)
NO (1) NO760239L (en)
SE (1) SE7600846L (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2644833A1 (en) * 1976-10-05 1978-04-20 Boehringer Sohn Ingelheim NEW 1-ARYLOXY-2-HYDROXY-3-ALKYLENE AMINOPROPANES AND METHOD FOR THE PRODUCTION THEREOF
DE3015991A1 (en) * 1980-04-25 1981-11-05 C.H. Boehringer Sohn, 6507 Ingelheim NEW 1-ARYLOXY-3-ALKYLAMINO-2-PROPANOLS AND METHOD FOR THE PRODUCTION THEREOF
DE3133719A1 (en) * 1981-08-26 1983-03-10 Boehringer Ingelheim KG, 6507 Ingelheim NEW 1-ARYLOXY-3-ALKINYLAMINO-2-PROPANOLS AND METHOD FOR THE PRODUCTION THEREOF
DE3133678A1 (en) * 1981-08-26 1983-03-17 Boehringer Ingelheim KG, 6507 Ingelheim NEW L-ARYLOXY-3-ALKYLAMINO-2-PROPANOLS AND METHOD FOR THEIR PRODUCTION
CA1262729A (en) * 1983-10-19 1989-11-07 Leo Alig Phenoxypropanolamines
US5166218A (en) * 1983-10-19 1992-11-24 Hoffmann-La Roche Inc. Phenoxypropanolamines and pharmaceutical compositions thereof
DE3407695A1 (en) * 1984-03-02 1985-09-12 Röhm Pharma GmbH, 6108 Weiterstadt PTERIDINE COMPOUNDS WITH PHARMACEUTICAL EFFECTIVENESS
US4652584A (en) * 1984-07-13 1987-03-24 Mcneilab, Inc. Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension
US4728666A (en) * 1985-12-11 1988-03-01 Mcneilab, Inc. Heteroaromatic acetylenes useful as antihypertensive agents
US4663334A (en) * 1985-12-11 1987-05-05 Mcneilab, Inc. Heteroaromatic acetylenes useful as antihypertensive agents
DE3866984D1 (en) * 1987-07-21 1992-01-30 Hoffmann La Roche Phenoxypropanolamine.
DE3852551T2 (en) * 1987-12-11 1995-05-18 Mitsui Petrochemical Ind AMINES AND THEIR USE.
SE8705150D0 (en) * 1987-12-23 1987-12-23 Haessle Ab NOVEL ANTIARRHYTHMIC AGENTS
EP0444138B1 (en) * 1988-11-17 1996-04-17 Physical Sciences, Inc. Electrocatalyst, methods for preparing it, electrodes prepared therefrom and methods for using them
US4969332A (en) * 1989-01-27 1990-11-13 Allied-Signal, Inc. Controller for a three-wheel turbocharger

Also Published As

Publication number Publication date
JPS51125334A (en) 1976-11-01
FI753667A (en) 1976-07-28
DE2503222A1 (en) 1976-07-29
SE7600846L (en) 1976-07-27
AT340389B (en) 1977-12-12
NO760239L (en) 1976-07-28
DK29376A (en) 1976-07-28
GR59280B (en) 1977-12-06
ATA939075A (en) 1977-04-15
LU74246A1 (en) 1977-03-18
CH623024A5 (en) 1981-05-15

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