ES443626A1 - Arufua 66 deokishitetorasaikurin no seiho - Google Patents

Arufua 66 deokishitetorasaikurin no seiho

Info

Publication number
ES443626A1
ES443626A1 ES443626A ES443626A ES443626A1 ES 443626 A1 ES443626 A1 ES 443626A1 ES 443626 A ES443626 A ES 443626A ES 443626 A ES443626 A ES 443626A ES 443626 A1 ES443626 A1 ES 443626A1
Authority
ES
Spain
Prior art keywords
group
hydrogenation
acid addition
addition salt
isomer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES443626A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES443626A1 publication Critical patent/ES443626A1/en
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/22—Organic complexes
    • B01J31/2204—Organic complexes the ligands containing oxygen or sulfur as complexing atoms
    • B01J31/2208—Oxygen, e.g. acetylacetonates
    • B01J31/2226—Anionic ligands, i.e. the overall ligand carries at least one formal negative charge
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
    • B01J31/2404—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0073—Rhodium compounds
    • C07F15/008—Rhodium compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/50—Organo-phosphines
    • C07F9/5045—Complexes or chelates of phosphines with metallic compounds or metals
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F41—WEAPONS
    • F41A—FUNCTIONAL FEATURES OR DETAILS COMMON TO BOTH SMALLARMS AND ORDNANCE, e.g. CANNONS; MOUNTINGS FOR SMALLARMS OR ORDNANCE
    • F41A9/00—Feeding or loading of ammunition; Magazines; Guiding means for the extracting of cartridges
    • F41A9/01—Feeding of unbelted ammunition
    • F41A9/24—Feeding of unbelted ammunition using a movable magazine or clip as feeding element
    • F41A9/26—Feeding of unbelted ammunition using a movable magazine or clip as feeding element using a revolving drum magazine
    • F41A9/27—Feeding of unbelted ammunition using a movable magazine or clip as feeding element using a revolving drum magazine in revolver-type guns
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F41—WEAPONS
    • F41A—FUNCTIONAL FEATURES OR DETAILS COMMON TO BOTH SMALLARMS AND ORDNANCE, e.g. CANNONS; MOUNTINGS FOR SMALLARMS OR ORDNANCE
    • F41A9/00—Feeding or loading of ammunition; Magazines; Guiding means for the extracting of cartridges
    • F41A9/29—Feeding of belted ammunition
    • F41A9/30—Sprocket-type belt transporters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/60—Reduction reactions, e.g. hydrogenation
    • B01J2231/64—Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
    • B01J2231/641—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes
    • B01J2231/645—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes of C=C or C-C triple bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/80—Complexes comprising metals of Group VIII as the central metal
    • B01J2531/82—Metals of the platinum group
    • B01J2531/822—Rhodium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Improved process of hydrogenating the exocyclic methylene group of a 6-deoxy-6-demotyl-6-methylenthothracycline or an acid addition salt thereof, characterized by carrying out the hydrogenation at a temperature of from about 20º to about 100ºC, at a pressure of from about 1 to about 100 atmospheres, under near neutral conditions or in the weakly acidic tetracycline acid addition salt in the presence of a catalytic amount of a compound of the formula Rh (OCOR) 2 (p [C6H5] 3) wherein R is selected from the group consisting of hydrogen, alkyl having 1 to 6 carbon atoms, chloromethyl, dichloromethyl, trichloromethyl, fluomethyl, difluomethyl, trifluomethyl, phenyl, chlorophenyl, tolyl, and anisyl, whereby the hydrogenation of the group of exocyclic methylene advances with a stereaselectivity that favors the alpha-isomer over the beta-isomer. (Machine-translation by Google Translate, not legally binding)
ES443626A 1974-12-19 1975-12-18 Arufua 66 deokishitetorasaikurin no seiho Expired ES443626A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53445274A 1974-12-19 1974-12-19

Publications (1)

Publication Number Publication Date
ES443626A1 true ES443626A1 (en) 1977-05-01

Family

ID=24130096

Family Applications (1)

Application Number Title Priority Date Filing Date
ES443626A Expired ES443626A1 (en) 1974-12-19 1975-12-18 Arufua 66 deokishitetorasaikurin no seiho

Country Status (26)

Country Link
JP (1) JPS5186457A (en)
AR (1) AR208347A1 (en)
AT (1) AT344320B (en)
AU (1) AU476488B2 (en)
BE (1) BE836775A (en)
BG (1) BG24798A3 (en)
CH (1) CH609042A5 (en)
CS (1) CS203099B2 (en)
DD (1) DD123600A5 (en)
DE (1) DE2554564A1 (en)
DK (1) DK151224C (en)
ES (1) ES443626A1 (en)
FI (1) FI59395C (en)
FR (1) FR2295014A1 (en)
HU (1) HU173508B (en)
IE (1) IE42180B1 (en)
LU (1) LU74054A1 (en)
NL (1) NL164849B (en)
NO (1) NO146236C (en)
PH (1) PH13795A (en)
PL (1) PL105946B1 (en)
RO (1) RO72846A (en)
SE (1) SE426587B (en)
SU (1) SU799650A3 (en)
YU (1) YU39474B (en)
ZA (1) ZA757902B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE435619C (en) * 1973-02-01 1985-11-18 Pfizer PROCEDURE FOR PREPARING A 6ALFA DEOXYTETRACYCLINE
DK386784A (en) * 1983-08-17 1985-02-18 Hovione Int Ltd PROCEDURE FOR PREPARING ALFA-6-DESOXY-TETRACYCLINES

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1368431A (en) * 1970-07-22 1974-09-25 Johnson Matthey Co Ltd Rhodium complex and methods of preparing the complex
SE435619C (en) * 1973-02-01 1985-11-18 Pfizer PROCEDURE FOR PREPARING A 6ALFA DEOXYTETRACYCLINE

Also Published As

Publication number Publication date
RO72846A (en) 1982-04-12
AU476488B2 (en) 1976-09-23
DK151224B (en) 1987-11-16
BE836775A (en) 1976-06-18
CH609042A5 (en) 1979-02-15
NL164849B (en) 1980-09-15
NO754085L (en) 1976-06-22
NO146236C (en) 1982-08-25
FI753459A (en) 1976-06-20
AU8766875A (en) 1976-09-23
FR2295014A1 (en) 1976-07-16
ZA757902B (en) 1976-12-29
ATA937675A (en) 1977-11-15
YU39474B (en) 1984-12-31
PH13795A (en) 1980-10-01
SU799650A3 (en) 1981-01-23
DK576575A (en) 1976-06-20
SE7513091L (en) 1976-06-21
FI59395C (en) 1981-08-10
FI59395B (en) 1981-04-30
NL7514840A (en) 1976-06-22
JPS5186457A (en) 1976-07-29
HU173508B (en) 1979-05-28
CS203099B2 (en) 1981-02-27
FR2295014B1 (en) 1978-10-06
AT344320B (en) 1978-07-10
YU305075A (en) 1982-05-31
DK151224C (en) 1988-05-16
DE2554564A1 (en) 1976-07-01
LU74054A1 (en) 1976-11-11
IE42180L (en) 1976-06-19
NO146236B (en) 1982-05-18
AR208347A1 (en) 1976-12-20
PL105946B1 (en) 1979-11-30
JPS5324944B2 (en) 1978-07-24
DD123600A5 (en) 1977-01-05
SE426587B (en) 1983-01-31
IE42180B1 (en) 1980-06-18
BG24798A3 (en) 1978-05-12

Similar Documents

Publication Publication Date Title
ES382975A1 (en) Process for reactivating a reforming catalyst
ES402057A1 (en) Compounds tetracloroftalidos cromogenicos (Machine-translation by Google Translate, not legally binding)
ES443626A1 (en) Arufua 66 deokishitetorasaikurin no seiho
ES323287A1 (en) Procedure for preparing substituted pirrolindazol compounds. (Machine-translation by Google Translate, not legally binding)
ES404745A1 (en) Cephalosporin compounds
ES278356A1 (en) Procedure for the preparation of substitute hydrazine compounds (Machine-translation by Google Translate, not legally binding)
ES407059A1 (en) Tris-organotin sulfolenes and sulfolanes
ES389350A1 (en) Method of controlling weeds with organotin compounds
GB1367602A (en) Process for preparing amino-substituted phosphonates
ES415114A1 (en) Process for the production of organotin halides
ES380390A1 (en) Chemical products and processes
ES403446A1 (en) Oxadiazolone compounds
GB1343470A (en) Complex compounds of metals belonging to group viii of the periodic table and process for preparaing the same
ES425197A1 (en) Penicillanic acids their production and their medicinal use
ES432863A1 (en) Method of producing 1-n-l- - alpha-hydroxy-ypsilon-aminobutyryl -xk-62-2
ES419839A1 (en) Substituted methylene diamines
ES434355A1 (en) Device to vary the width of via, especially of agricultural vehicles. (Machine-translation by Google Translate, not legally binding)
ES337700A1 (en) Procedure for preparing molluscyced agents. (Machine-translation by Google Translate, not legally binding)
ES382794A1 (en) Nickel compounds
ES252263A1 (en) Process for preparing derivatives of 7-sulfamyl-6-trifluoromethyl-1, 2, 4-benzothiadazine-1, 1-dioxide
ES287028A1 (en) Procedure for the manufacture of new basic derivatives of fenoxazine and its salts (Machine-translation by Google Translate, not legally binding)
ES281441A1 (en) A procedure for the manufacture of pharmaceutical compounds (Machine-translation by Google Translate, not legally binding)
ES443438A1 (en) A method for the control of corrosión in an aqueous system. (Machine-translation by Google Translate, not legally binding)
ES411331A1 (en) Procedure for the obtaining of 4 and 5-nitroimidazoles. (Machine-translation by Google Translate, not legally binding)
ES355907A3 (en) Procedure for preparing 3-imino-benzisotiazolinas substituted in the atom of nitrogen. (Machine-translation by Google Translate, not legally binding)