ES442994A1 - Un procedimiento para la obtencion de 7-cloro-1-(2-(dietila-mino)-etil) -5-(0-fluorofenil) -1,3-dihidro -2h -1,4-benzo- diazepin-2-ona. - Google Patents
Un procedimiento para la obtencion de 7-cloro-1-(2-(dietila-mino)-etil) -5-(0-fluorofenil) -1,3-dihidro -2h -1,4-benzo- diazepin-2-ona.Info
- Publication number
- ES442994A1 ES442994A1 ES442994A ES442994A ES442994A1 ES 442994 A1 ES442994 A1 ES 442994A1 ES 442994 A ES442994 A ES 442994A ES 442994 A ES442994 A ES 442994A ES 442994 A1 ES442994 A1 ES 442994A1
- Authority
- ES
- Spain
- Prior art keywords
- benzodiazepin
- diethylamino
- fluorophenyl
- chloro
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- PAAZPARNPHGIKF-UHFFFAOYSA-N 1,2-dibromoethane Chemical compound BrCCBr PAAZPARNPHGIKF-UHFFFAOYSA-N 0.000 abstract 1
- 125000004198 2-fluorophenyl group Chemical group [H]C1=C([H])C(F)=C(*)C([H])=C1[H] 0.000 abstract 1
- GWTNBENXABQHCR-UHFFFAOYSA-N 7-chloro-1-[2-(diethylamino)ethyl]-4-oxido-3H-1,4-benzodiazepin-4-ium-2-one Chemical compound ClC=1C=CC2=C(C=[N+](CC(N2CCN(CC)CC)=O)[O-])C1 GWTNBENXABQHCR-UHFFFAOYSA-N 0.000 abstract 1
- 238000003747 Grignard reaction Methods 0.000 abstract 1
- CCOALSBHGYNLLS-UHFFFAOYSA-M [Br-].FC1=CC=CC=C1[Mg+] Chemical compound [Br-].FC1=CC=CC=C1[Mg+] CCOALSBHGYNLLS-UHFFFAOYSA-M 0.000 abstract 1
- SAADBVWGJQAEFS-UHFFFAOYSA-N flurazepam Chemical compound N=1CC(=O)N(CCN(CC)CC)C2=CC=C(Cl)C=C2C=1C1=CC=CC=C1F SAADBVWGJQAEFS-UHFFFAOYSA-N 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- ZMANZCXQSJIPKH-UHFFFAOYSA-N triethylamine Natural products CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5171174A GB1455675A (en) | 1974-11-29 | 1974-11-29 | Production of 2-chloro-1-2-diethylamino-ethyl-5-o-fluorophenyl- 1,3-dihydro-2h-1,4-benzodiazepin-2-one |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES442994A1 true ES442994A1 (es) | 1977-04-16 |
Family
ID=10461085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES442994A Expired ES442994A1 (es) | 1974-11-29 | 1975-11-26 | Un procedimiento para la obtencion de 7-cloro-1-(2-(dietila-mino)-etil) -5-(0-fluorofenil) -1,3-dihidro -2h -1,4-benzo- diazepin-2-ona. |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS5176284A (en:Method) |
| AT (1) | AT350057B (en:Method) |
| CA (1) | CA1044232A (en:Method) |
| DK (1) | DK519775A (en:Method) |
| ES (1) | ES442994A1 (en:Method) |
| FI (1) | FI753334A7 (en:Method) |
| GB (1) | GB1455675A (en:Method) |
| NL (1) | NL7513754A (en:Method) |
| NO (1) | NO754025L (en:Method) |
| SE (1) | SE7513444L (en:Method) |
| YU (1) | YU298175A (en:Method) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4837038A (en:Method) * | 1971-09-14 | 1973-05-31 |
-
1974
- 1974-11-29 GB GB5171174A patent/GB1455675A/en not_active Expired
-
1975
- 1975-11-19 DK DK519775A patent/DK519775A/da unknown
- 1975-11-21 CA CA240,171A patent/CA1044232A/en not_active Expired
- 1975-11-25 YU YU02981/75A patent/YU298175A/xx unknown
- 1975-11-25 NL NL7513754A patent/NL7513754A/xx not_active Application Discontinuation
- 1975-11-26 ES ES442994A patent/ES442994A1/es not_active Expired
- 1975-11-26 FI FI753334A patent/FI753334A7/fi not_active Application Discontinuation
- 1975-11-27 JP JP50141230A patent/JPS5176284A/ja active Pending
- 1975-11-28 SE SE7513444A patent/SE7513444L/xx unknown
- 1975-11-28 NO NO754025A patent/NO754025L/no unknown
- 1975-11-28 AT AT905775A patent/AT350057B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5176284A (en) | 1976-07-01 |
| GB1455675A (en) | 1976-11-17 |
| SE7513444L (sv) | 1976-05-31 |
| NO754025L (en:Method) | 1976-06-01 |
| CA1044232A (en) | 1978-12-12 |
| ATA905775A (de) | 1978-10-15 |
| FI753334A7 (en:Method) | 1976-05-30 |
| AT350057B (de) | 1979-05-10 |
| NL7513754A (nl) | 1976-06-01 |
| DK519775A (da) | 1976-05-30 |
| YU298175A (en) | 1982-02-28 |
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