ES441002A1 - Oxaprostaglandins - Google Patents
OxaprostaglandinsInfo
- Publication number
- ES441002A1 ES441002A1 ES441002A ES441002A ES441002A1 ES 441002 A1 ES441002 A1 ES 441002A1 ES 441002 A ES441002 A ES 441002A ES 441002 A ES441002 A ES 441002A ES 441002 A1 ES441002 A1 ES 441002A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compound
- ligation
- tie
- oxaprostaglandins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A procedure to prepare oxaprostaglandins of the following structure: ** (See formula) ** in which R is hydrogen or an alkyl of 1 to 3 carbon atoms; W is a single tie or a double cis tie; Z is a single ligation or a double trans ligation; n is an integer from 0 to 2 and m is an integer ranging from 1 to 5, provided that the sum of n and m does not exceed 6, and THP is 2-tetrahydropyranil; characterized by the fact that: a compound of the formula is reacted: ** (See formula) ** with an iluro of the formula (C6H5) 3P = CH-CH2CH2CH2-COOH and, when required, subsequently reduce the product thus formed to yield a compound in which: n, m R and Z represent what is indicated above and W is a single bond. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25921572A | 1972-06-02 | 1972-06-02 | |
| US05/355,644 US4094899A (en) | 1972-06-02 | 1973-04-30 | Oxaprostaglandins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES441002A1 true ES441002A1 (en) | 1977-03-01 |
Family
ID=26947161
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES441003A Expired ES441003A1 (en) | 1972-06-02 | 1975-09-16 | Oxaprostaglandins |
| ES441002A Expired ES441002A1 (en) | 1972-06-02 | 1975-09-16 | Oxaprostaglandins |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES441003A Expired ES441003A1 (en) | 1972-06-02 | 1975-09-16 | Oxaprostaglandins |
Country Status (19)
| Country | Link |
|---|---|
| JP (3) | JPS5314062B2 (en) |
| AR (2) | AR199300A1 (en) |
| CA (1) | CA1095034A (en) |
| CH (3) | CH586716A5 (en) |
| DD (2) | DD109859A5 (en) |
| DE (2) | DE2344838C3 (en) |
| DK (1) | DK143498C (en) |
| ES (2) | ES441003A1 (en) |
| FI (1) | FI55995C (en) |
| GB (3) | GB1440601A (en) |
| IE (1) | IE38568B1 (en) |
| IL (2) | IL42373A (en) |
| IN (1) | IN138739B (en) |
| LU (1) | LU67738A1 (en) |
| NL (1) | NL162902C (en) |
| NO (1) | NO145438C (en) |
| PH (3) | PH11300A (en) |
| SE (4) | SE415756B (en) |
| YU (1) | YU36497B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO143741C (en) * | 1972-07-13 | 1981-04-08 | Pfizer | ANALOGY PROCEDURE FOR THE PREPARATION OF PHYSIOLOGICALLY ACTIVE PROSTAGLAND CONNECTIONS OF THE E AND F SERIES |
| US11756356B2 (en) | 2019-08-28 | 2023-09-12 | Igloocompany Pte. Ltd. | System and method for controlling multiple locks |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3538120A (en) * | 1967-05-22 | 1970-11-03 | Ciba Geigy Corp | Cyclopentyl-alkanoic acids |
| ZA721159B (en) * | 1971-03-22 | 1972-12-27 | Ici Ltd | Process for the separation of the c-15 epimers of 20-ethyl-9a,11alpha,15-trihydroxy-5-cis-13-trans-prostadienoic acid |
-
1973
- 1973-05-28 IL IL42373A patent/IL42373A/en unknown
- 1973-05-28 SE SE7307521A patent/SE415756B/en unknown
- 1973-05-28 IL IL7350311A patent/IL50311A/en unknown
- 1973-05-29 FI FI1735/73A patent/FI55995C/en active
- 1973-05-30 GB GB2584673A patent/GB1440601A/en not_active Expired
- 1973-05-30 IN IN1265/CAL/73A patent/IN138739B/en unknown
- 1973-05-30 GB GB2306775A patent/GB1440603A/en not_active Expired
- 1973-05-30 GB GB2306575A patent/GB1440602A/en not_active Expired
- 1973-06-01 DE DE2344838A patent/DE2344838C3/en not_active Expired
- 1973-06-01 DK DK303973A patent/DK143498C/en not_active IP Right Cessation
- 1973-06-01 IE IE881/73A patent/IE38568B1/en unknown
- 1973-06-01 DE DE2327813A patent/DE2327813A1/en not_active Withdrawn
- 1973-06-01 CH CH415576A patent/CH586716A5/xx not_active IP Right Cessation
- 1973-06-01 CH CH797573A patent/CH590224A5/xx not_active IP Right Cessation
- 1973-06-01 CH CH415476A patent/CH589074A5/xx not_active IP Right Cessation
- 1973-06-01 CA CA173,035A patent/CA1095034A/en not_active Expired
- 1973-06-02 JP JP6244973A patent/JPS5314062B2/ja not_active Expired
- 1973-06-04 NL NL7307740.A patent/NL162902C/en not_active IP Right Cessation
- 1973-06-04 LU LU67738A patent/LU67738A1/xx unknown
- 1973-06-04 YU YU01469/73A patent/YU36497B/en unknown
- 1973-06-04 AR AR248400A patent/AR199300A1/en active
- 1973-06-04 DD DD171300A patent/DD109859A5/xx unknown
- 1973-06-04 DD DD182818A patent/DD124594A5/xx unknown
- 1973-06-04 PH PH14690A patent/PH11300A/en unknown
-
1974
- 1974-01-29 AR AR252103A patent/AR203386A1/en active
- 1974-03-11 NO NO740849A patent/NO145438C/en unknown
-
1975
- 1975-04-07 PH PH17029A patent/PH11931A/en unknown
- 1975-04-07 PH PH17030A patent/PH12035A/en unknown
- 1975-09-16 ES ES441003A patent/ES441003A1/en not_active Expired
- 1975-09-16 ES ES441002A patent/ES441002A1/en not_active Expired
-
1976
- 1976-07-19 SE SE7608221A patent/SE418857B/en unknown
- 1976-07-19 SE SE7608222A patent/SE7608222L/en unknown
- 1976-07-19 SE SE7608223A patent/SE7608223L/en not_active Application Discontinuation
- 1976-09-08 JP JP51107651A patent/JPS5231054A/en active Granted
- 1976-09-08 JP JP51107650A patent/JPS5239629A/en active Pending
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