ES440922A1 - Un procedimiento para la preparacion de un peptido con una estructura ciclica de disulfuro. - Google Patents

Un procedimiento para la preparacion de un peptido con una estructura ciclica de disulfuro.

Info

Publication number
ES440922A1
ES440922A1 ES440922A ES440922A ES440922A1 ES 440922 A1 ES440922 A1 ES 440922A1 ES 440922 A ES440922 A ES 440922A ES 440922 A ES440922 A ES 440922A ES 440922 A1 ES440922 A1 ES 440922A1
Authority
ES
Spain
Prior art keywords
peptide
cyclic
cysteine
amino acid
alkylthio group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES440922A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Armour Pharmaceutical Co
Original Assignee
Armour Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Armour Pharmaceutical Co filed Critical Armour Pharmaceutical Co
Publication of ES440922A1 publication Critical patent/ES440922A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/067General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/585Calcitonins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/15Oxytocin or vasopressin; related peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/16Somatostatin; related peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/26Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES440922A 1974-09-12 1975-09-12 Un procedimiento para la preparacion de un peptido con una estructura ciclica de disulfuro. Expired ES440922A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US505344A US3929758A (en) 1974-09-12 1974-09-12 Cyclization of cysteine-containing peptides

Publications (1)

Publication Number Publication Date
ES440922A1 true ES440922A1 (es) 1977-06-16

Family

ID=24009941

Family Applications (1)

Application Number Title Priority Date Filing Date
ES440922A Expired ES440922A1 (es) 1974-09-12 1975-09-12 Un procedimiento para la preparacion de un peptido con una estructura ciclica de disulfuro.

Country Status (16)

Country Link
US (1) US3929758A (es)
JP (1) JPS5833864B2 (es)
AU (1) AU498757B2 (es)
BE (1) BE833336A (es)
CA (1) CA1045117A (es)
DE (1) DE2540780A1 (es)
DK (1) DK409775A (es)
ES (1) ES440922A1 (es)
FR (1) FR2284591A1 (es)
GB (1) GB1527252A (es)
HU (1) HU175202B (es)
IT (1) IT1042496B (es)
LU (1) LU73386A1 (es)
NL (1) NL179909C (es)
SU (1) SU849998A3 (es)
YU (1) YU39747B (es)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4033940A (en) * 1975-11-12 1977-07-05 Armour Pharmaceutical Company Cyclization of peptides
US4066634A (en) * 1976-08-31 1978-01-03 American Home Products Corporation Purification of synthetic somatostatin
US4304692A (en) * 1978-07-24 1981-12-08 Armour Pharmaceutical Company Synthesis of biologically active peptides
US4212795A (en) * 1978-11-13 1980-07-15 Armour Pharmaceutical Company Cyclization of peptides
US4401593A (en) * 1982-02-12 1983-08-30 Armour Pharmaceutical Company Glycine - 8 calcitonin
US4391747A (en) * 1982-02-12 1983-07-05 Armour Pharmaceutical Company Des asparagine-3-calcitonin
US4397780A (en) * 1982-02-12 1983-08-09 Armour Pharmaceutical Company Leucine22 -calcitonin
US4388235A (en) * 1982-02-12 1983-06-14 Armour Pharmaceutical Company Synthesis of peptides
US4469632A (en) * 1982-09-24 1984-09-04 Armour Pharmaceutical Company D-Arginine24 calcitonin
US4444681A (en) * 1982-09-24 1984-04-24 Armour Pharmaceutical Company L-Tyrosine21 calcitonin
US4451395A (en) * 1982-11-08 1984-05-29 Armour Pharmaceutical Company Des-serine2 -des-tyrosine22 calcitonin
JPS60500054A (ja) * 1983-02-15 1985-01-17 ア−マ−・フア−マシユ−テイカル・カンパニ− デス−アスパラギン−3−カルシトニン
WO1984003280A1 (en) * 1983-02-15 1984-08-30 Armour Pharma Glycine-8 calcitonin
US4549986A (en) * 1983-12-23 1985-10-29 The Salk Institute For Biological Studies Human CGRP
US4623716A (en) 1984-11-01 1986-11-18 Usv Pharmaceutical Corp. Process for the preparation and purification of peptides
JPH0517511Y2 (es) * 1985-09-30 1993-05-11
US4644054A (en) * 1985-10-01 1987-02-17 Kempe Tomas G Calcitonin analogs with amino acid substituents at position 31
US4658014A (en) * 1985-12-20 1987-04-14 Kempe Tomas G Synthetic peptides with calcitonin-like activity
US4687839A (en) * 1985-12-23 1987-08-18 Kempe Tomas G Calcitonin gene related peptide analogs with C-terminal D-amino acid substituents
US4697002A (en) * 1985-12-23 1987-09-29 Kempe Tomas G Calcitonin gene related peptide analogs with amino acid subdstituents at the penultimate position 36
US4820804A (en) * 1987-04-21 1989-04-11 Rorer Pharmaceutical Corporation Analogs of [1,7-di-alanine, des-19-leucine]calcitonin
US4824936A (en) * 1987-05-06 1989-04-25 Rorer Pharmaceutical Corporation (19-Alanine) calcitonin
JP2682061B2 (ja) * 1988-10-07 1997-11-26 藤沢薬品工業株式会社 ペプチドの分子内ジスルフィド結合の形成法
ES2051647B1 (es) * 1992-12-10 1995-01-16 Lipotec Sa Procedimiento para la preparacion de calcitonina de salmon.
US5674850A (en) * 1993-12-23 1997-10-07 Ferring Ab High purity desmopressin produced in large single batches
NZ268442A (en) * 1993-06-29 1996-09-25 Ferring Bv Aqueous composition of desmopressin for nasal spray administration
WO1995001368A1 (en) * 1993-06-29 1995-01-12 Ferring B.V. Improved synthesis of cyclic peptides
US5482931A (en) * 1993-06-29 1996-01-09 Ferring Ab Stabilized pharmaceutical peptide compositions
US5500413A (en) * 1993-06-29 1996-03-19 Ferring Ab Process for manufacture of 1-deamino-8-D-arginine vasopressin
SE9400918L (sv) * 1994-03-18 1995-09-19 Anne Fjellstad Paulsen Stabiliserad komposition för oral administrering av peptider
US5763398A (en) * 1996-06-20 1998-06-09 Ferring B.V. Nasal administration of desmopressin
US5922680A (en) * 1996-10-23 1999-07-13 Ferring, B.V. Stabilized composition for oral administration of peptides
EP1452868A2 (en) 2003-02-27 2004-09-01 Pepscan Systems B.V. Method for selecting a candidate drug compound
US7723474B2 (en) * 2003-10-21 2010-05-25 The Regents Of The University Of California Molecules that selectively home to vasculature of pre-malignant dysplastic lesions or malignancies
WO2008077621A1 (de) * 2006-12-23 2008-07-03 Aplagen Gmbh Verfahren zur ausbildung von disulfidbrücken
US20140086895A1 (en) 2011-05-10 2014-03-27 Universite De Rouen Methods and pharmaceutical compositions for the treatment of autoimmune diseases
GB201313352D0 (en) 2013-07-26 2013-09-11 Isis Innovation Identification of peptide ligands
US9925233B2 (en) 2015-01-30 2018-03-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
WO2016184784A1 (en) 2015-05-15 2016-11-24 INSERM (Institut National de la Santé et de la Recherche Médicale) Peptides including binding domain of plasmodium falciparum proteins (cbp1 and cbp2) to chemokine cx3cl1

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3560521A (en) * 1967-08-07 1971-02-02 Merck & Co Inc Blocking groups for cysteine containing peptides
US3679655A (en) * 1968-06-28 1972-07-25 Hoechst Ag N,n-disubstituted aminoethylcarbamyl protecting groups for cysteine
US3849388A (en) * 1968-10-15 1974-11-19 Ciba Geigy Corp Analogues of human thyrocalcitonin
DE1950711A1 (de) * 1968-10-15 1970-04-30 Ciba Geigy Neue Peptide und Verfahren zu ihrer Herstellung
GB1294771A (en) * 1969-01-31 1972-11-01 Sandoz Ltd Thyrocalcitonin derivative
CH523868A (de) * 1969-10-22 1972-06-15 Ciba Geigy Ag Verfahren zur Herstellung neuer Dotriacontapeptidamide und ihrer Derivate
US3801561A (en) * 1970-10-29 1974-04-02 Sandoz Ltd Derivatives of salmon thyrocalcitonin
ZA723287B (en) * 1971-06-18 1973-02-28 Hoffmann La Roche Nonapeptides and processes for the preparation thereof
BE785933A (fr) * 1971-07-07 1973-01-08 Ciba Geigy Procede de preparation de peptides contenant de la cystine

Also Published As

Publication number Publication date
JPS5833864B2 (ja) 1983-07-22
YU230075A (en) 1982-02-28
HU175202B (hu) 1980-06-28
LU73386A1 (es) 1976-04-13
DE2540780A1 (de) 1976-04-01
AU8473775A (en) 1977-03-17
AU498757B2 (en) 1979-03-22
US3929758A (en) 1975-12-30
FR2284591B1 (es) 1978-12-01
JPS5156448A (es) 1976-05-18
DK409775A (da) 1976-03-13
CA1045117A (en) 1978-12-26
YU39747B (en) 1985-04-30
DE2540780C2 (es) 1989-05-24
GB1527252A (en) 1978-10-04
FR2284591A1 (fr) 1976-04-09
IT1042496B (it) 1980-01-30
SU849998A3 (ru) 1981-07-23
NL179909C (nl) 1986-12-01
BE833336A (fr) 1975-12-31
NL7510761A (nl) 1976-03-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202