ES435208A1 - 20-hydroxymethyl-prostadienoic acid derivatives - Google Patents

20-hydroxymethyl-prostadienoic acid derivatives

Info

Publication number
ES435208A1
ES435208A1 ES435208A ES435208A ES435208A1 ES 435208 A1 ES435208 A1 ES 435208A1 ES 435208 A ES435208 A ES 435208A ES 435208 A ES435208 A ES 435208A ES 435208 A1 ES435208 A1 ES 435208A1
Authority
ES
Spain
Prior art keywords
formula
see formula
heterocyclic group
acid
hydroxymethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES435208A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2397174A external-priority patent/JPS50116453A/ja
Priority claimed from JP11106174A external-priority patent/JPS5139648A/en
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of ES435208A1 publication Critical patent/ES435208A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A production process for derivatives of 20-hydroxymethylprostadienoic acid represented by the formula: **(See formula)** where A represents (see formula) or (see formula) and R1 and R2, which may be the same or different, each represent a hydrogen atom or a lower alkyl group and their non-toxic and pharmacologically acceptable salts, whose procedure consists in separating a heterocyclic group from a prostadiene acid derivative, represented by the formula: **(See formula)** where A, R1 and R2 have the meaning given above and R3, R4 and R5, which may be the same or different, each represent a hydrogen atom or a heterocyclic group, at least one of said radicals being R3, R4 and R5 a heterocyclic group, by treating said derivative with an acid in a solvent. (Machine-translation by Google Translate, not legally binding)
ES435208A 1974-02-28 1975-02-28 20-hydroxymethyl-prostadienoic acid derivatives Expired ES435208A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2397174A JPS50116453A (en) 1974-02-28 1974-02-28
JP11106174A JPS5139648A (en) 1974-09-27 1974-09-27 Shinkina 166 arukiru 200 hidorokishimechirupurosutajensanjudotai no seiho

Publications (1)

Publication Number Publication Date
ES435208A1 true ES435208A1 (en) 1977-05-01

Family

ID=26361422

Family Applications (1)

Application Number Title Priority Date Filing Date
ES435208A Expired ES435208A1 (en) 1974-02-28 1975-02-28 20-hydroxymethyl-prostadienoic acid derivatives

Country Status (4)

Country Link
DE (1) DE2508218A1 (en)
ES (1) ES435208A1 (en)
FR (1) FR2262516A1 (en)
GB (1) GB1483316A (en)

Also Published As

Publication number Publication date
GB1483316A (en) 1977-08-17
FR2262516A1 (en) 1975-09-26
DE2508218A1 (en) 1975-09-25

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