ES431009A1 - Process for the preparation of benzylidene derivatives - Google Patents

Process for the preparation of benzylidene derivatives

Info

Publication number
ES431009A1
ES431009A1 ES431009A ES431009A ES431009A1 ES 431009 A1 ES431009 A1 ES 431009A1 ES 431009 A ES431009 A ES 431009A ES 431009 A ES431009 A ES 431009A ES 431009 A1 ES431009 A1 ES 431009A1
Authority
ES
Spain
Prior art keywords
formula
preparation
reacted
see formula
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES431009A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ISF SpA
Original Assignee
ISF SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ISF SpA filed Critical ISF SpA
Publication of ES431009A1 publication Critical patent/ES431009A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedure for the preparation of derivatives of 3-benzylidenhydrazino-6-aminopyridazine, of the formula **(See formula)** in which R represents methyl, ethyl, propyl, hydroxyethyl or 2-hydroxypropyl, that constitute intermediate compounds in the synthesis of pharmacologically active substances, characterized in that a thiopyridazine of the formula is reacted **(See formula)** in which X represents Cl, Br or S-CH3 with an amino alcohol of the formula **(See formula)** and by which the thus obtained substituted dialkylamino thiomethylpyridazine is reacted with hydrazine, preferably in the presence of an aprotic solvent, and is then treated with benzaldehyde to obtain the desired compounds. (Machine-translation by Google Translate, not legally binding)
ES431009A 1974-05-09 1974-10-15 Process for the preparation of benzylidene derivatives Expired ES431009A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2248674 1974-05-09

Publications (1)

Publication Number Publication Date
ES431009A1 true ES431009A1 (en) 1976-10-16

Family

ID=11196911

Family Applications (1)

Application Number Title Priority Date Filing Date
ES431009A Expired ES431009A1 (en) 1974-05-09 1974-10-15 Process for the preparation of benzylidene derivatives

Country Status (8)

Country Link
JP (1) JPS50142579A (en)
AR (1) AR201706A1 (en)
BE (1) BE821389A (en)
DE (1) DE2450873A1 (en)
ES (1) ES431009A1 (en)
FR (1) FR2270248B1 (en)
GB (1) GB1424789A (en)
ZA (1) ZA746669B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU176972B (en) * 1977-06-13 1981-06-28 Gyogyszerkutato Intezet Process for producing new piridazinyl-hydrasone derivatives
DE2965377D1 (en) * 1978-10-02 1983-06-16 Lepetit Spa 6-amino substituted n-pyrrolyl-3-pyridazine amines, their preparation, and pharmaceutically antihypertensive compositions containing them
HU179191B (en) * 1979-05-07 1982-09-28 Gyogyszerkutato Intezet New process for preparing 6-/substituted amino/-3-pyridazinyl-hydrazines and salts thereof

Also Published As

Publication number Publication date
JPS50142579A (en) 1975-11-17
BE821389A (en) 1975-02-17
DE2450873A1 (en) 1975-11-13
FR2270248B1 (en) 1977-07-08
FR2270248A1 (en) 1975-12-05
AR201706A1 (en) 1975-04-08
GB1424789A (en) 1976-02-11
ZA746669B (en) 1975-11-26

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