ES425971A1 - Procedimiento para la preparacion de 1,3,4 - trimetil - 2- (3,4,5-trimetoxibencil)- 1,2,5,6-tetrahidropiridina. - Google Patents
Procedimiento para la preparacion de 1,3,4 - trimetil - 2- (3,4,5-trimetoxibencil)- 1,2,5,6-tetrahidropiridina.Info
- Publication number
- ES425971A1 ES425971A1 ES425971A ES425971A ES425971A1 ES 425971 A1 ES425971 A1 ES 425971A1 ES 425971 A ES425971 A ES 425971A ES 425971 A ES425971 A ES 425971A ES 425971 A1 ES425971 A1 ES 425971A1
- Authority
- ES
- Spain
- Prior art keywords
- trimethyl
- tetrahydropyridine
- trimethoxybenzyl
- analgesic composition
- analgesic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Abstract
PROCEDIMIENTO DE OBTENCION DE 1,3,4-TRIMETIL-2-(3,4,5-TRIMETOXIBENZIL)-1,2,5,6,-TETRAHIDROPIRIDINA. SE PARTE DEL CLORURO DE DE 1,3,4-TRIMETIL-(3,4,5,TRIMETOXIBENCIL)-1,2,5,6-TETRAHIDROPIRIDANIO QUE SE LE SOMETE A UNA REACCION DE TRANSPOSICION DE STEVENS, EN PRSENCIA DE UNA DISOLUCION ETEREA DE FENIL-LITIO, RECIENTEMENTE PREPARADO, A LA TEMPERATURA DE SULFURO DE LA MEZCLA Y BAJO ATMOSFERA INERTE. EL COMPUESTO ASI OBTENIDO SE TRANSFORMA EN UNA DE SUS SALES DE ADICION CON ACIDOS FARMACEUTICAMENTE ACEPTABLES, COMO EL CLORHIDRATO. ESTE COMPUESTO PUEDE EMPLEARSE COMO ANALGESICO.
Priority Applications (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES425971A ES425971A1 (es) | 1974-05-04 | 1974-05-04 | Procedimiento para la preparacion de 1,3,4 - trimetil - 2- (3,4,5-trimetoxibencil)- 1,2,5,6-tetrahidropiridina. |
BE155740A BE828349A (fr) | 1974-05-04 | 1975-04-24 | Procede pour la preparation de 1,3,4-trimethyl-2(3,4,5-trimethoxybenzyl) -1,2,5,6,-tetrahydropyridine |
DE19752518514 DE2518514A1 (de) | 1974-05-04 | 1975-04-25 | 1,3,4-trimethyl-2-(3,4,5-trimethoxybenzyl)-1,2,5,6-tetrahydropyridin, verfahren zu seiner herstellung sowie es enthaltende arzneimittel |
FR7513284A FR2269345B1 (es) | 1974-05-04 | 1975-04-28 | |
US05/572,863 US4001414A (en) | 1974-05-04 | 1975-04-29 | 1,3,4-trimethyl-2-(3,4,5-trimethoxybenzyl)-1,2,5,6-tetrahydropyridine and analgesic composition and method using it |
AR258544A AR202749A1 (es) | 1974-05-04 | 1975-04-29 | Procedimiento para la preparacion de 1,3,4-trimetil-2(3,4,5-trimetoxibencil)-1,25,6-tetrahidropiridina |
AT334475A AT342048B (de) | 1974-05-04 | 1975-04-30 | Verfahren zur herstellung des neuen 1,3,4-trimethyl-2- (3,4,5-trimethoxybenzyl)-1,2,5,6-tetrahydropyridins und seiner saureadditionssalze |
GB1791475A GB1476111A (en) | 1974-05-04 | 1975-04-30 | 1-substituted 3,4,5-trimethoxybenzenes |
SE7505050A SE7505050L (sv) | 1974-05-04 | 1975-04-30 | Sett att framstella 1,3,4-trimetyl-2-(3,4,5-trimetoxibensyl)-1,2,5,6-tetrahydropyridin. |
CA226,058A CA1041516A (en) | 1974-05-04 | 1975-05-01 | Process for the preparation of 1,3,4-trimethyl-2-(3,4,5-trimethoxybenzyl)-1,2,5,6-tetrahydropyridine |
CH568175A CH612938A5 (es) | 1974-05-04 | 1975-05-02 | |
JP50053799A JPS50151880A (es) | 1974-05-04 | 1975-05-02 | |
NL7505252A NL7505252A (nl) | 1974-05-04 | 1975-05-02 | Werkwijze voor het bereiden van geneesmiddelen en werkwijze voor het bereiden van een nieuw pyridinederivaat. |
AU80743/75A AU475157B2 (en) | 1974-05-04 | 1975-05-02 | l, 3, 4-TRIMETHYL-2-(3, 4, 5-TRIMETHOXYBENZYL)-l, 2 TETRAHYDRO-PYRIDINE, ITS ADDITION SALTS, 3, 4, 5 TRIMETHOXPHGNYL-(3, 4-DIMETHYL-2-PYRIDYL0-CARBINOL AND PROCESS FORTHE PREPARATION OFTHESE COMPOUNDS |
SU2130153A SU562195A3 (ru) | 1974-05-04 | 1975-05-04 | Способ получени 1,3,4-триметил2,(3,4,5-триметоксибензил)1,2,5,6-тетрагидропиридина или их солей |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES425971A ES425971A1 (es) | 1974-05-04 | 1974-05-04 | Procedimiento para la preparacion de 1,3,4 - trimetil - 2- (3,4,5-trimetoxibencil)- 1,2,5,6-tetrahidropiridina. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES425971A1 true ES425971A1 (es) | 1976-09-16 |
Family
ID=8466595
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES425971A Expired ES425971A1 (es) | 1974-05-04 | 1974-05-04 | Procedimiento para la preparacion de 1,3,4 - trimetil - 2- (3,4,5-trimetoxibencil)- 1,2,5,6-tetrahidropiridina. |
Country Status (14)
Country | Link |
---|---|
US (1) | US4001414A (es) |
JP (1) | JPS50151880A (es) |
AR (1) | AR202749A1 (es) |
AT (1) | AT342048B (es) |
AU (1) | AU475157B2 (es) |
BE (1) | BE828349A (es) |
CA (1) | CA1041516A (es) |
CH (1) | CH612938A5 (es) |
DE (1) | DE2518514A1 (es) |
ES (1) | ES425971A1 (es) |
FR (1) | FR2269345B1 (es) |
NL (1) | NL7505252A (es) |
SE (1) | SE7505050L (es) |
SU (1) | SU562195A3 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4175197A (en) * | 1974-09-06 | 1979-11-20 | Eli Lilly And Company | 1,3,4-Trisubstituted-4-aryl-1,4,5,6-tetra-hydropyridines |
EP0004727B1 (en) * | 1978-04-12 | 1981-08-12 | Imperial Chemical Industries Plc | Blood platelet aggregation inhibitory pyridine derivatives, pharmaceutical compositions thereof, and processes for their manufacture |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3553223A (en) * | 1968-01-05 | 1971-01-05 | Hoffmann La Roche | Acid catalyzed cyclization of tetrahydropyridines containing an electron withdrawing group on the nitrogen |
-
1974
- 1974-05-04 ES ES425971A patent/ES425971A1/es not_active Expired
-
1975
- 1975-04-24 BE BE155740A patent/BE828349A/xx unknown
- 1975-04-25 DE DE19752518514 patent/DE2518514A1/de active Pending
- 1975-04-28 FR FR7513284A patent/FR2269345B1/fr not_active Expired
- 1975-04-29 US US05/572,863 patent/US4001414A/en not_active Expired - Lifetime
- 1975-04-29 AR AR258544A patent/AR202749A1/es active
- 1975-04-30 AT AT334475A patent/AT342048B/de not_active IP Right Cessation
- 1975-04-30 SE SE7505050A patent/SE7505050L/xx unknown
- 1975-05-01 CA CA226,058A patent/CA1041516A/en not_active Expired
- 1975-05-02 NL NL7505252A patent/NL7505252A/xx not_active Application Discontinuation
- 1975-05-02 CH CH568175A patent/CH612938A5/xx not_active IP Right Cessation
- 1975-05-02 AU AU80743/75A patent/AU475157B2/en not_active Expired
- 1975-05-02 JP JP50053799A patent/JPS50151880A/ja active Pending
- 1975-05-04 SU SU2130153A patent/SU562195A3/ru active
Also Published As
Publication number | Publication date |
---|---|
FR2269345B1 (es) | 1978-11-10 |
AU8074375A (en) | 1976-08-12 |
JPS50151880A (es) | 1975-12-06 |
DE2518514A1 (de) | 1975-11-13 |
NL7505252A (nl) | 1975-11-06 |
US4001414A (en) | 1977-01-04 |
ATA334475A (de) | 1977-07-15 |
SU562195A3 (ru) | 1977-06-15 |
BE828349A (fr) | 1975-10-24 |
AU475157B2 (en) | 1976-08-12 |
AT342048B (de) | 1978-03-10 |
AR202749A1 (es) | 1975-07-15 |
SE7505050L (sv) | 1975-11-05 |
CH612938A5 (es) | 1979-08-31 |
CA1041516A (en) | 1978-10-31 |
FR2269345A1 (es) | 1975-11-28 |
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