ES423368A1 - Procedimiento de preparacion del acido 4,8 - dimetoxi - fu-ro(3',2' - f) - benzoxazol - 2 - il - acetohidroxamico. - Google Patents
Procedimiento de preparacion del acido 4,8 - dimetoxi - fu-ro(3',2' - f) - benzoxazol - 2 - il - acetohidroxamico.Info
- Publication number
- ES423368A1 ES423368A1 ES423368A ES423368A ES423368A1 ES 423368 A1 ES423368 A1 ES 423368A1 ES 423368 A ES423368 A ES 423368A ES 423368 A ES423368 A ES 423368A ES 423368 A1 ES423368 A1 ES 423368A1
- Authority
- ES
- Spain
- Prior art keywords
- dimethoxy
- furo
- benzoxazol
- pharmacologically active
- acethydroxamic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- RRUDCFGSUDOHDG-UHFFFAOYSA-N acetohydroxamic acid Chemical compound CC(O)=NO RRUDCFGSUDOHDG-UHFFFAOYSA-N 0.000 title 1
- WTDHULULXKLSOZ-UHFFFAOYSA-N Hydroxylamine hydrochloride Chemical compound Cl.ON WTDHULULXKLSOZ-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000000304 vasodilatating effect Effects 0.000 abstract 2
- BCMCBBGGLRIHSE-UHFFFAOYSA-N 1,3-benzoxazole Chemical compound C1=CC=C2OC=NC2=C1 BCMCBBGGLRIHSE-UHFFFAOYSA-N 0.000 abstract 1
- YWKRFJSQRANHKQ-UHFFFAOYSA-N 3-ethoxy-2-imino-3-oxopropanoic acid hydrochloride Chemical compound Cl.N=C(C(=O)OCC)C(=O)O YWKRFJSQRANHKQ-UHFFFAOYSA-N 0.000 abstract 1
- MKFDYQKJCBJSAE-UHFFFAOYSA-N 4-amino-2,5-dimethoxy-1-benzofuran-3-ol Chemical compound NC1=C(C=CC2=C1C(=C(O2)OC)O)OC MKFDYQKJCBJSAE-UHFFFAOYSA-N 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 230000003555 analeptic effect Effects 0.000 abstract 1
- 230000001078 anti-cholinergic effect Effects 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 239000003420 antiserotonin agent Substances 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7305816A FR2218092B1 (es) | 1973-02-19 | 1973-02-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES423368A1 true ES423368A1 (es) | 1976-06-01 |
Family
ID=9115052
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES423368A Expired ES423368A1 (es) | 1973-02-19 | 1974-02-18 | Procedimiento de preparacion del acido 4,8 - dimetoxi - fu-ro(3',2' - f) - benzoxazol - 2 - il - acetohidroxamico. |
Country Status (15)
Country | Link |
---|---|
US (1) | US3922280A (es) |
JP (1) | JPS49110700A (es) |
AU (1) | AU476756B2 (es) |
BE (1) | BE810683A (es) |
CA (1) | CA1012542A (es) |
CH (1) | CH578570A5 (es) |
DE (1) | DE2404413A1 (es) |
ES (1) | ES423368A1 (es) |
FR (1) | FR2218092B1 (es) |
GB (1) | GB1417822A (es) |
LU (1) | LU69362A1 (es) |
NL (1) | NL7402222A (es) |
SE (1) | SE382815B (es) |
SU (1) | SU501672A3 (es) |
ZA (1) | ZA74404B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9911071D0 (en) * | 1999-05-12 | 1999-07-14 | Darwin Discovery Ltd | Hydroxamic and carboxylic acid derivatives |
JP4790594B2 (ja) | 2003-02-25 | 2011-10-12 | トポターゲット ユーケー リミテッド | Hdacインヒビターとしての、二環式ヘテロアリール基を含むヒドロキサム酸化合物 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1087779A (en) * | 1964-12-18 | 1967-10-18 | Monsanto Chem Australia Ltd | Preparation of 2-substituted benzoxazoles |
-
1973
- 1973-02-19 FR FR7305816A patent/FR2218092B1/fr not_active Expired
-
1974
- 1974-01-21 ZA ZA740404A patent/ZA74404B/xx unknown
- 1974-01-22 GB GB285874A patent/GB1417822A/en not_active Expired
- 1974-01-30 DE DE2404413A patent/DE2404413A1/de active Pending
- 1974-02-01 AU AU65110/74A patent/AU476756B2/en not_active Expired
- 1974-02-06 BE BE140614A patent/BE810683A/xx unknown
- 1974-02-08 LU LU69362A patent/LU69362A1/xx unknown
- 1974-02-14 US US442757A patent/US3922280A/en not_active Expired - Lifetime
- 1974-02-18 ES ES423368A patent/ES423368A1/es not_active Expired
- 1974-02-18 SU SU1999213A patent/SU501672A3/ru active
- 1974-02-18 CA CA192,851A patent/CA1012542A/fr not_active Expired
- 1974-02-18 SE SE7402117A patent/SE382815B/xx not_active IP Right Cessation
- 1974-02-18 NL NL7402222A patent/NL7402222A/xx not_active Application Discontinuation
- 1974-02-19 JP JP49019875A patent/JPS49110700A/ja active Pending
- 1974-02-19 CH CH229074A patent/CH578570A5/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FR2218092A1 (es) | 1974-09-13 |
BE810683A (fr) | 1974-08-06 |
DE2404413A1 (de) | 1974-08-29 |
CA1012542A (fr) | 1977-06-21 |
NL7402222A (es) | 1974-08-21 |
LU69362A1 (es) | 1974-10-01 |
AU6511074A (en) | 1975-08-07 |
ZA74404B (en) | 1974-11-27 |
SU501672A3 (ru) | 1976-01-30 |
JPS49110700A (es) | 1974-10-22 |
GB1417822A (en) | 1975-12-17 |
US3922280A (en) | 1975-11-25 |
AU476756B2 (en) | 1976-09-30 |
CH578570A5 (es) | 1976-08-13 |
FR2218092B1 (es) | 1976-03-05 |
SE382815B (sv) | 1976-02-16 |
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