CH610322A5 - Process for the preparation of 1,4-benzodioxins - Google Patents

Process for the preparation of 1,4-benzodioxins

Info

Publication number
CH610322A5
CH610322A5 CH1522575A CH1522575A CH610322A5 CH 610322 A5 CH610322 A5 CH 610322A5 CH 1522575 A CH1522575 A CH 1522575A CH 1522575 A CH1522575 A CH 1522575A CH 610322 A5 CH610322 A5 CH 610322A5
Authority
CH
Switzerland
Prior art keywords
preparation
compounds
radical
benzodioxins
antibronchial
Prior art date
Application number
CH1522575A
Inventor
Claude Fauran
Guy Bourgery
Guy Raynaud
Yves Bailly
Original Assignee
Delalande Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande Sa filed Critical Delalande Sa
Publication of CH610322A5 publication Critical patent/CH610322A5/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Compounds of formula (I) <IMAGE> in which: - n is an integer equal to 2 or 3; and - R1 and R2 each denote a C1 to C4 alkyl radical or form, jointly with the nitrogen atom to which they are bonded, a pyrrolidino, piperidino or hexamethyleneimino radical, are prepared, as well as their pharmacologically acceptable salts. A corresponding acetyl-5-hydroxy-1,4-benzodioxin is condensed with a chloroalkylamine in acetone medium and in the presence of potassium carbonate. These new compounds can be used for the preparation of medicaments for the treatment of circulatory insufficiency and of asthma and have the following pharmacological activities: vasodilatory, antibronchial- constricting, hypotensive and spasmolytic properties.
CH1522575A 1975-11-05 1975-11-24 Process for the preparation of 1,4-benzodioxins CH610322A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7533783A FR2330390A2 (en) 1975-11-05 1975-11-05 NEW 1,4-BENZODIOXANES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION

Publications (1)

Publication Number Publication Date
CH610322A5 true CH610322A5 (en) 1979-04-12

Family

ID=9162052

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1522575A CH610322A5 (en) 1975-11-05 1975-11-24 Process for the preparation of 1,4-benzodioxins

Country Status (14)

Country Link
JP (2) JPS5259166A (en)
AU (1) AU499442B2 (en)
BE (1) BE835828A (en)
CA (1) CA1065321A (en)
CH (1) CH610322A5 (en)
DE (1) DE2552868A1 (en)
ES (1) ES443357A1 (en)
FR (1) FR2330390A2 (en)
GB (1) GB1486356A (en)
IT (1) IT1059875B (en)
LU (1) LU73931A1 (en)
NL (1) NL7514416A (en)
SE (1) SE7513235L (en)
SU (2) SU586840A3 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2449088A1 (en) * 1979-02-14 1980-09-12 Delalande Sa 5-Piperazinyl-propoxy-1,4-benzodioxan derivs. - useful as hypotensives and vasodilators
FR2537970B1 (en) * 1982-12-15 1986-08-14 Delalande Sa NOVEL AMINOALKOXY AROMATIC DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION IN THERAPEUTICS
US6514996B2 (en) 1995-05-19 2003-02-04 Kyowa Hakko Kogyo Co., Ltd. Derivatives of benzofuran or benzodioxole
CA2272327A1 (en) * 1996-11-19 1998-05-28 Kyowa Hakko Kogyo Co., Ltd. Oxygen-containing heterocyclic compounds

Also Published As

Publication number Publication date
FR2330390A2 (en) 1977-06-03
SU645576A3 (en) 1979-01-30
AU499442B2 (en) 1979-04-12
GB1486356A (en) 1977-09-21
CA1065321A (en) 1979-10-30
IT1059875B (en) 1982-06-21
ES443357A1 (en) 1977-05-01
AU8729875A (en) 1977-06-09
SE7513235L (en) 1977-05-06
JPS5259167A (en) 1977-05-16
LU73931A1 (en) 1976-11-11
BE835828A (en) 1976-05-21
NL7514416A (en) 1977-05-09
DE2552868A1 (en) 1977-05-18
JPS5259166A (en) 1977-05-16
SU586840A3 (en) 1977-12-30

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Legal Events

Date Code Title Description
PL Patent ceased