ES422837A1 - Procedimiento para la preparacion de derivados ergolinicos. - Google Patents
Procedimiento para la preparacion de derivados ergolinicos.Info
- Publication number
- ES422837A1 ES422837A1 ES422837A ES422837A ES422837A1 ES 422837 A1 ES422837 A1 ES 422837A1 ES 422837 A ES422837 A ES 422837A ES 422837 A ES422837 A ES 422837A ES 422837 A1 ES422837 A1 ES 422837A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- carbon atoms
- hydrogen
- lower alkyl
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- AWFDCTXCTHGORH-HGHGUNKESA-N 6-[4-[(6ar,9r,10ar)-5-bromo-7-methyl-6,6a,8,9,10,10a-hexahydro-4h-indolo[4,3-fg]quinoline-9-carbonyl]piperazin-1-yl]-1-methylpyridin-2-one Chemical class O=C([C@H]1CN([C@H]2[C@@H](C=3C=CC=C4NC(Br)=C(C=34)C2)C1)C)N(CC1)CCN1C1=CC=CC(=O)N1C AWFDCTXCTHGORH-HGHGUNKESA-N 0.000 title abstract 2
- -1 alkyl radical Chemical class 0.000 abstract 7
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 229910052736 halogen Chemical group 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- KAESVJOAVNADME-UHFFFAOYSA-N 1H-pyrrole Natural products C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000003754 ethoxycarbonyl group Chemical group C(=O)(OCC)* 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical compound [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Substances C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1994173 | 1973-02-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES422837A1 true ES422837A1 (es) | 1976-09-16 |
Family
ID=11162515
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES422837A Expired ES422837A1 (es) | 1973-02-02 | 1974-02-01 | Procedimiento para la preparacion de derivados ergolinicos. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US3972883A (en, 2012) |
| JP (1) | JPS49102700A (en, 2012) |
| AT (1) | AT336201B (en, 2012) |
| BE (1) | BE810510A (en, 2012) |
| CA (1) | CA1022549A (en, 2012) |
| CH (1) | CH599956A5 (en, 2012) |
| DE (1) | DE2404924B2 (en, 2012) |
| ES (1) | ES422837A1 (en, 2012) |
| FR (1) | FR2215957B1 (en, 2012) |
| GB (1) | GB1430912A (en, 2012) |
| HU (1) | HU166851B (en, 2012) |
| IL (1) | IL44119A (en, 2012) |
| NL (1) | NL7400790A (en, 2012) |
| SU (1) | SU557757A3 (en, 2012) |
| YU (1) | YU19774A (en, 2012) |
| ZA (1) | ZA74675B (en, 2012) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CS177530B1 (en) * | 1974-07-19 | 1977-07-29 | Miroslav Semonsky | New nbeta-substituted derivatives of b-beta-aminoethyl-ergoline-i their salts and methods for the production thereof |
| CS195905B1 (en) * | 1976-12-06 | 1980-02-29 | Milos Beran | 6-substituted derivatives of d-8-ergolin-i-ylacetic acid amide and process for preparing thereof |
| IT1193467B (it) * | 1978-01-26 | 1988-07-08 | Simes | Carbammati di omolisergoli (8 beta-idrossietilergoline) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3228943A (en) * | 1962-06-11 | 1966-01-11 | Lumilysergol derivatives | |
| BE712054A (en, 2012) * | 1967-03-16 | 1968-07-15 | ||
| FR7775M (en, 2012) * | 1967-06-28 | 1970-03-23 | ||
| CH517762A (de) * | 1968-08-27 | 1972-01-15 | Spofa Vereinigte Pharma Werke | Verfahren zur Herstellung eines neuen D-6-Methylergolenderivates |
| NL7102982A (en, 2012) * | 1970-03-20 | 1971-09-22 | Farmaceutici Italia | |
| NL159384B (nl) * | 1971-03-13 | 1979-02-15 | Farmaceutici Italia | Werkwijze voor het bereiden van een geneesmiddel met een adrenolytische activiteit, alsmede werkwijze voor het bereiden van een ester van 1-methyl-10-methoxylumilysergol. |
-
1974
- 1974-01-21 NL NL7400790A patent/NL7400790A/xx not_active Application Discontinuation
- 1974-01-28 GB GB388774A patent/GB1430912A/en not_active Expired
- 1974-01-28 US US05/436,927 patent/US3972883A/en not_active Expired - Lifetime
- 1974-01-28 YU YU00197/74A patent/YU19774A/xx unknown
- 1974-01-29 JP JP49011529A patent/JPS49102700A/ja active Pending
- 1974-01-29 FR FR7402829A patent/FR2215957B1/fr not_active Expired
- 1974-01-29 CA CA191,132A patent/CA1022549A/en not_active Expired
- 1974-01-30 IL IL44119A patent/IL44119A/en unknown
- 1974-01-30 AT AT74574A patent/AT336201B/de not_active IP Right Cessation
- 1974-01-30 HU HUFA959A patent/HU166851B/hu unknown
- 1974-01-30 SU SU1990334A patent/SU557757A3/ru active
- 1974-02-01 ES ES422837A patent/ES422837A1/es not_active Expired
- 1974-02-01 BE BE140467A patent/BE810510A/xx unknown
- 1974-02-01 ZA ZA740675A patent/ZA74675B/xx unknown
- 1974-02-01 CH CH145674A patent/CH599956A5/xx not_active IP Right Cessation
- 1974-02-01 DE DE2404924A patent/DE2404924B2/de active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ATA74574A (de) | 1976-08-15 |
| NL7400790A (en, 2012) | 1974-08-06 |
| BE810510A (fr) | 1974-08-01 |
| FR2215957B1 (en, 2012) | 1978-01-06 |
| YU19774A (en) | 1982-05-31 |
| CH599956A5 (en, 2012) | 1978-06-15 |
| ZA74675B (en) | 1974-12-24 |
| DE2404924B2 (de) | 1978-08-03 |
| IL44119A (en) | 1977-01-31 |
| US3972883A (en) | 1976-08-03 |
| GB1430912A (en) | 1976-04-07 |
| FR2215957A1 (en, 2012) | 1974-08-30 |
| DE2404924C3 (en, 2012) | 1979-03-29 |
| JPS49102700A (en, 2012) | 1974-09-27 |
| AT336201B (de) | 1977-04-25 |
| IL44119A0 (en) | 1974-05-16 |
| SU557757A3 (ru) | 1977-05-05 |
| DE2404924A1 (de) | 1974-08-22 |
| HU166851B (en, 2012) | 1975-06-28 |
| CA1022549A (en) | 1977-12-13 |
| AU6498474A (en) | 1975-07-31 |
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