ES422801A1 - Procedimiento para la preparacion de nuevos compuestos n- adamantil-2-carboxi-1-azaciclicos. - Google Patents
Procedimiento para la preparacion de nuevos compuestos n- adamantil-2-carboxi-1-azaciclicos.Info
- Publication number
- ES422801A1 ES422801A1 ES422801A ES422801A ES422801A1 ES 422801 A1 ES422801 A1 ES 422801A1 ES 422801 A ES422801 A ES 422801A ES 422801 A ES422801 A ES 422801A ES 422801 A1 ES422801 A1 ES 422801A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- carbon atoms
- formula
- alkyl
- hydrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000004432 carbon atom Chemical group C* 0.000 abstract 10
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- -1 1-adamantyl group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004069 aziridinyl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000002485 inorganic esters Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000002895 organic esters Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
- C07D203/14—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom with carbocyclic rings directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00090474A US3810884A (en) | 1970-11-17 | 1970-11-17 | 1-adamantyl-2-carboxy-azacyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES422801A1 true ES422801A1 (es) | 1976-05-01 |
Family
ID=22222925
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES397058A Expired ES397058A1 (es) | 1970-11-17 | 1971-11-16 | Procedimiento para preparar nuevos compuestos n-sustituidos- 2 - carboxi-1-azaciclicos. |
| ES422801A Expired ES422801A1 (es) | 1970-11-17 | 1974-01-01 | Procedimiento para la preparacion de nuevos compuestos n- adamantil-2-carboxi-1-azaciclicos. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES397058A Expired ES397058A1 (es) | 1970-11-17 | 1971-11-16 | Procedimiento para preparar nuevos compuestos n-sustituidos- 2 - carboxi-1-azaciclicos. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3810884A (es) |
| AT (3) | AT319261B (es) |
| BE (1) | BE775371A (es) |
| CA (1) | CA962267A (es) |
| DE (1) | DE2156499A1 (es) |
| ES (2) | ES397058A1 (es) |
| FR (1) | FR2114006B1 (es) |
| GB (1) | GB1373239A (es) |
| HU (1) | HU164333B (es) |
| IE (1) | IE35813B1 (es) |
| IL (1) | IL38157A0 (es) |
| NL (1) | NL7115752A (es) |
| ZA (1) | ZA717693B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3919254A (en) * | 1971-12-02 | 1975-11-11 | Hoffmann La Roche | Hydroxycitric acid derivatives |
| US3993668A (en) * | 1973-07-05 | 1976-11-23 | Hoffmann-La Roche Inc. | Hydroxycitric acid derivatives |
| US3993667A (en) * | 1973-07-05 | 1976-11-23 | Hoffmann-La Roche Inc. | Hydroxycitric acid derivatives |
| US3994927A (en) * | 1973-07-05 | 1976-11-30 | Hoffmann-La Roche Inc. | Hydroxycitric acid derivatives |
| US3879400A (en) * | 1973-11-16 | 1975-04-22 | Upjohn Co | 1-Lower alkyl-(1-adamantylmethyl)piperidines and process for their preparation |
| US4066833A (en) * | 1976-11-22 | 1978-01-03 | The United States Of America As Represented By The Secretary Of The Navy | 2,3,7,8-Tetraazaspiro [4.4]nonane, 2,3,7,8-tetraazaspiro-[4.4]nona-2,7-diene and derivatives |
| US4170707A (en) * | 1976-11-22 | 1979-10-09 | The United States Of America As Represented By The Secretary Of The Navy | Method for preparing 3,8-dicarbomethoxy-2,3,7,8-tetraazaspiro[4.4]nona-1,6-diene |
| US4946839A (en) * | 1987-07-17 | 1990-08-07 | Fidia-Georgetown Institute For The Neurosciences | Azetidine derivatives, compositions and methods of treating |
| US7056935B2 (en) * | 1995-06-07 | 2006-06-06 | Gpi Nil Holdings, Inc. | Rotamase enzyme activity inhibitors |
| US5859031A (en) * | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
-
1970
- 1970-11-17 US US00090474A patent/US3810884A/en not_active Expired - Lifetime
-
1971
- 1971-11-13 DE DE19712156499 patent/DE2156499A1/de active Pending
- 1971-11-16 AT AT1050473A patent/AT319261B/de not_active IP Right Cessation
- 1971-11-16 BE BE775371A patent/BE775371A/xx unknown
- 1971-11-16 HU HUSCHE363*1A patent/HU164333B/hu unknown
- 1971-11-16 CA CA127,837A patent/CA962267A/en not_active Expired
- 1971-11-16 IL IL38157A patent/IL38157A0/xx unknown
- 1971-11-16 AT AT989271A patent/AT318638B/de not_active IP Right Cessation
- 1971-11-16 ES ES397058A patent/ES397058A1/es not_active Expired
- 1971-11-16 FR FR7140984A patent/FR2114006B1/fr not_active Expired
- 1971-11-16 GB GB5317771A patent/GB1373239A/en not_active Expired
- 1971-11-16 ZA ZA717693A patent/ZA717693B/xx unknown
- 1971-11-16 AT AT1050573A patent/AT319262B/de not_active IP Right Cessation
- 1971-11-16 NL NL7115752A patent/NL7115752A/xx unknown
- 1971-11-16 IE IE1443/71A patent/IE35813B1/xx unknown
-
1974
- 1974-01-01 ES ES422801A patent/ES422801A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AT318638B (de) | 1974-11-11 |
| FR2114006A1 (es) | 1972-06-30 |
| IE35813B1 (en) | 1976-05-26 |
| DE2156499A1 (de) | 1972-05-18 |
| CA962267A (en) | 1975-02-04 |
| IL38157A0 (en) | 1972-01-27 |
| AT319262B (de) | 1974-12-10 |
| ES397058A1 (es) | 1975-03-16 |
| BE775371A (fr) | 1972-05-16 |
| HU164333B (es) | 1974-01-28 |
| US3810884A (en) | 1974-05-14 |
| FR2114006B1 (es) | 1974-11-15 |
| ZA717693B (en) | 1972-08-30 |
| IE35813L (en) | 1972-05-17 |
| NL7115752A (es) | 1972-05-19 |
| GB1373239A (en) | 1974-11-06 |
| AT319261B (de) | 1974-12-10 |
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