ES420179A1 - Un procedimiento para la preparacion de iminas triciclicas con actividad farmacodinamica. - Google Patents
Un procedimiento para la preparacion de iminas triciclicas con actividad farmacodinamica.Info
- Publication number
- ES420179A1 ES420179A1 ES420179A ES420179A ES420179A1 ES 420179 A1 ES420179 A1 ES 420179A1 ES 420179 A ES420179 A ES 420179A ES 420179 A ES420179 A ES 420179A ES 420179 A1 ES420179 A1 ES 420179A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- lower alkyl
- atom
- halogen
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002466 imines Chemical class 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000005843 halogen group Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000005278 alkyl sulfonyloxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002911 monocyclic heterocycle group Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 230000003285 pharmacodynamic effect Effects 0.000 abstract 1
- -1 phenylsulfonyloxy group Chemical group 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
- C07C65/34—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups polycyclic
- C07C65/36—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups polycyclic containing rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/12—[b,e]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D337/12—[b,e]-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1497270A CH541545A (de) | 1970-10-09 | 1970-10-09 | Verfahren zur Herstellung von tricyclischen Iminen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES420179A1 true ES420179A1 (es) | 1976-05-01 |
Family
ID=4405292
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES395844A Expired ES395844A1 (es) | 1970-10-09 | 1971-10-08 | Un procedimiento para la preparacion de iminas triciclicas,farmacodinamicante activas. |
| ES420179A Expired ES420179A1 (es) | 1970-10-09 | 1973-11-02 | Un procedimiento para la preparacion de iminas triciclicas con actividad farmacodinamica. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES395844A Expired ES395844A1 (es) | 1970-10-09 | 1971-10-08 | Un procedimiento para la preparacion de iminas triciclicas,farmacodinamicante activas. |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US3803234A (es) |
| KR (1) | KR780000028B1 (es) |
| AR (1) | AR194102A1 (es) |
| AT (2) | AT312575B (es) |
| AU (1) | AU458443B2 (es) |
| BE (1) | BE773649A (es) |
| BG (2) | BG20775A3 (es) |
| BR (1) | BR7106595D0 (es) |
| CA (1) | CA967150A (es) |
| CH (1) | CH541545A (es) |
| CS (1) | CS179960B2 (es) |
| DE (1) | DE2150079A1 (es) |
| DK (1) | DK138641B (es) |
| ES (2) | ES395844A1 (es) |
| FI (1) | FI54100C (es) |
| FR (1) | FR2110323B1 (es) |
| GB (1) | GB1334967A (es) |
| HU (1) | HU162983B (es) |
| IE (1) | IE35691B1 (es) |
| IL (1) | IL37705A (es) |
| NL (1) | NL7113295A (es) |
| NO (1) | NO135180C (es) |
| PH (1) | PH9973A (es) |
| PL (1) | PL83435B1 (es) |
| RO (1) | RO61541A (es) |
| SE (1) | SE374912B (es) |
| SU (2) | SU495830A3 (es) |
| ZA (1) | ZA716071B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4003915A (en) * | 1970-10-09 | 1977-01-18 | Hoffmann-La Roche Inc. | Tricyclic imines |
| US3954865A (en) * | 1972-04-27 | 1976-05-04 | E. I. Du Pont De Nemours And Company | N-cycloalkyl substituted-10,11-dihydro 5H-dibenzo[a,d] cyclohepten-5-imines |
| US3901945A (en) * | 1972-09-28 | 1975-08-26 | Du Pont | 1,1a,6,10b-tetrahydrodibenzo (a,e) cyclopropa (c) cyclohepten-6-imines |
| US3985895A (en) * | 1974-03-20 | 1976-10-12 | Hoffmann-La Roche Inc. | N,N-diethyl-N'-{dibenzo[b,e]thiepin-11(6H)-ylidene}-1,3-propanediamine and derivatives thereof |
| US4035509A (en) * | 1974-04-22 | 1977-07-12 | Syntex (U.S.A.) Inc. | Methods and compositions for the use of 2-carboxy-5-oxo-5H-dibenzo[a,d]cycloheptenes, salts and esters thereof |
| US4020094A (en) * | 1974-04-22 | 1977-04-26 | Syntex (U.S.A.) Inc. | 2-Substituted-5-oxo-5H-dibenzo[a,d]cycloheptenes, the salts and esters thereof, having pharmaceutical activity |
| US4041173A (en) * | 1975-10-06 | 1977-08-09 | Syntex (U.S.A.) Inc. | 2-Carboxy-(7-,8- and 9-substituted)-5-oxo-5H-dibenzo (a,d) cycloheptenes and the corresponding 10,11-dihydro compounds |
| US4795822A (en) * | 1984-05-23 | 1989-01-03 | Syntex (U.S.A.) Inc. | Nortriptyline conjugates to antigenic proteins and enzymes |
| JPH10504324A (ja) * | 1995-06-07 | 1998-04-28 | デイド、ケミストリー、システムズ、インコーポレイテッド | 薬物の免疫原その他の接合体の製造 |
| HRP970649B1 (en) * | 1997-12-01 | 2004-12-31 | Belupo Lijekovi I Kozmetika D | Dibenzosuberone derivatives and processes for their preparation |
-
1970
- 1970-10-09 CH CH1497270A patent/CH541545A/de not_active IP Right Cessation
-
1971
- 1971-09-10 ZA ZA716071A patent/ZA716071B/xx unknown
- 1971-09-13 AU AU33403/71A patent/AU458443B2/en not_active Expired
- 1971-09-13 IL IL37705A patent/IL37705A/xx unknown
- 1971-09-16 PH PH12843A patent/PH9973A/en unknown
- 1971-09-22 FI FI2650/71A patent/FI54100C/fi active
- 1971-09-24 BG BG018627A patent/BG20775A3/xx unknown
- 1971-09-24 BG BG020940A patent/BG20559A3/xx unknown
- 1971-09-28 NL NL7113295A patent/NL7113295A/xx unknown
- 1971-09-29 US US00184901A patent/US3803234A/en not_active Expired - Lifetime
- 1971-10-04 IE IE1243/71A patent/IE35691B1/xx unknown
- 1971-10-05 BR BR006595/71A patent/BR7106595D0/pt unknown
- 1971-10-06 SE SE7112643A patent/SE374912B/xx unknown
- 1971-10-07 KR KR7301448A patent/KR780000028B1/ko active
- 1971-10-07 GB GB4675171A patent/GB1334967A/en not_active Expired
- 1971-10-07 DE DE19712150079 patent/DE2150079A1/de active Pending
- 1971-10-07 CS CS7100007092A patent/CS179960B2/cs unknown
- 1971-10-08 RO RO68410A patent/RO61541A/ro unknown
- 1971-10-08 HU HUHO1425A patent/HU162983B/hu unknown
- 1971-10-08 DK DK491271AA patent/DK138641B/da unknown
- 1971-10-08 AT AT871371A patent/AT312575B/de active
- 1971-10-08 SU SU1704970A patent/SU495830A3/ru active
- 1971-10-08 BE BE773649A patent/BE773649A/xx unknown
- 1971-10-08 CA CA124,752A patent/CA967150A/en not_active Expired
- 1971-10-08 ES ES395844A patent/ES395844A1/es not_active Expired
- 1971-10-08 FR FR7136264A patent/FR2110323B1/fr not_active Expired
- 1971-10-08 NO NO3704/71A patent/NO135180C/no unknown
- 1971-10-08 AT AT1098072A patent/AT313252B/de not_active IP Right Cessation
- 1971-10-09 PL PL1971150975A patent/PL83435B1/pl unknown
-
1972
- 1972-05-08 AR AR241872A patent/AR194102A1/es active
-
1973
- 1973-05-25 SU SU1923838A patent/SU519124A3/ru active
- 1973-11-02 ES ES420179A patent/ES420179A1/es not_active Expired
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