ES417791A1 - 4-Hydroxy-3,5-di-alkyl-phenyl-propionic acid composition suitable as lipid lowering and anti-diabetic agents - Google Patents

4-Hydroxy-3,5-di-alkyl-phenyl-propionic acid composition suitable as lipid lowering and anti-diabetic agents

Info

Publication number
ES417791A1
ES417791A1 ES417791A ES417791A ES417791A1 ES 417791 A1 ES417791 A1 ES 417791A1 ES 417791 A ES417791 A ES 417791A ES 417791 A ES417791 A ES 417791A ES 417791 A1 ES417791 A1 ES 417791A1
Authority
ES
Spain
Prior art keywords
carbon atoms
stands
hydroxy
alkyl
propionic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES417791A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Farbwerke Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG, Farbwerke Hoechst AG filed Critical Hoechst AG
Publication of ES417791A1 publication Critical patent/ES417791A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/08Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Pharmaceutical compositions acting on the metabolism which contain as active derivatives of the 4-hydroxy-3,5-di-akylphenyl-propionic acid corresponding to the formula I and II O PARALLEL -CH2-CH2-C-X (I) O PARALLEL -CH2-CH2-C-OR3 n (II) wherein R1 and R2 which may be identical or different, each stands for an alkylradical having 1 to 8 carbon atoms, R3 stands for an alkylene radical having 2 to 12 carbon atoms, X stands for hydroxy, alkoxy having 1 to 18 carbon atoms, phenalkoxy having 1 to 4 alkyl carbon atoms, cycloalkoxy having 5 to 8 carbon atoms, -NR4R5 in which R4 stands for an alkyl group having 1 to 18 carbon atoms, R5 stands for a hydrogen atom or R4 and R5 may form with the nitrogen atom a heterocyclic six-membered ring which may carry another hetero atom and n is an integer from 2 to 4 and process for preparing them.
ES417791A 1972-08-18 1973-08-11 4-Hydroxy-3,5-di-alkyl-phenyl-propionic acid composition suitable as lipid lowering and anti-diabetic agents Expired ES417791A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2240609A DE2240609A1 (en) 1972-08-18 1972-08-18 METABOLIZING DERIVATIVES OF 4-HYDROXY-3,5-DI-ALKYLPHENYL-PROPIONIC ACID

Publications (1)

Publication Number Publication Date
ES417791A1 true ES417791A1 (en) 1976-06-01

Family

ID=5853878

Family Applications (1)

Application Number Title Priority Date Filing Date
ES417791A Expired ES417791A1 (en) 1972-08-18 1973-08-11 4-Hydroxy-3,5-di-alkyl-phenyl-propionic acid composition suitable as lipid lowering and anti-diabetic agents

Country Status (15)

Country Link
US (1) US3969530A (en)
JP (1) JPS4956948A (en)
BE (1) BE803771A (en)
CA (1) CA1014475A (en)
CH (1) CH590197A5 (en)
DD (1) DD108457A5 (en)
DE (1) DE2240609A1 (en)
ES (1) ES417791A1 (en)
FR (1) FR2196164B1 (en)
GB (1) GB1446781A (en)
HU (1) HU175933B (en)
IE (1) IE38096B1 (en)
IL (1) IL42998A (en)
NL (1) NL7311148A (en)
ZA (1) ZA735640B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4153597A (en) * 1978-06-26 1979-05-08 Uniroyal, Inc. Hindered phenolic nitro compounds as antioxidants
US4405807A (en) * 1980-01-14 1983-09-20 Mitsui Petrochemical Industries, Ltd. Tetrakis[3-(3,5-di-t-butyl-4-hydroxyphenyl)propionyloxymethyl]methane having a novel crystal structure and process for production thereof
JPS57185234A (en) * 1981-05-07 1982-11-15 Ihara Chem Ind Co Ltd Preparation of hydroxyphenylacetic acid
JPS57203030A (en) * 1981-06-05 1982-12-13 Ihara Chem Ind Co Ltd Preparation of hydroxyphenyl-substituted fatty acid
FI842618A (en) * 1984-06-28 1985-12-29 Neste Oy FRUIT PROCEDURE FOR FRAMSTAELLNING AV STEARYL - - (3,5-DIBUTYL-4-HYDROXYPHENYL) PROPIONAT OCH BIS- (- (3,5-DIBUTYL-4-HYDROXIBENZYL) -METHYL CARBOXYETHYL) SULFID.
DE3920616A1 (en) * 1989-06-23 1991-01-03 Boehringer Mannheim Gmbh MEDICINAL PRODUCTS CONTAINING DI-TERT.-BUTYLHYDROXYPHENYL DERIVATIVES AND NEW DERIVATIVES
CA2049481A1 (en) * 1990-08-27 1992-02-28 Jill Ann Panetta Method of treating inflammatory bowel disease
US5281623A (en) * 1990-08-27 1994-01-25 Eli Lilly And Company Method for treating inflammation
US5280046A (en) * 1991-02-22 1994-01-18 The University Of Colorado Foundation, Inc. Method of treating type I diabetes
DE4344180A1 (en) 1993-12-23 1995-06-29 Bayer Ag Use of anticorrosive agents in the production of isocyanate-based foams
FR2714376A1 (en) * 1993-12-29 1995-06-30 Khimbio Di:methyl amino ethyl phenyl propionate(s)
US5917044A (en) * 1997-04-15 1999-06-29 Uniroyal Chemical Company, Inc. Phenolic amides and their use as stabilizers
EP1871339A1 (en) * 2005-04-19 2008-01-02 Merck Patent GmbH Uv protection

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3068148A (en) * 1959-12-07 1962-12-11 Us Vitamin Pharm Corp Cis-cinnamic acid anti-inflammatory compositions and process of treating inflammation and capillary fragility
NL284831A (en) * 1961-10-30
US3644482A (en) * 1961-10-30 1972-02-22 Geigy Ag J R (4-hydroxy-5-alkylphenyl) alkanoic acid esters of polyols
JPS5112505B2 (en) * 1971-10-07 1976-04-20

Also Published As

Publication number Publication date
DE2240609A1 (en) 1974-02-28
ZA735640B (en) 1974-07-31
IE38096B1 (en) 1977-12-21
FR2196164B1 (en) 1977-07-15
FR2196164A1 (en) 1974-03-15
IE38096L (en) 1974-02-18
JPS4956948A (en) 1974-06-03
CA1014475A (en) 1977-07-26
AU5928873A (en) 1975-02-20
GB1446781A (en) 1976-08-18
BE803771A (en) 1974-02-20
US3969530A (en) 1976-07-13
NL7311148A (en) 1974-02-20
IL42998A (en) 1978-07-31
HU175933B (en) 1980-11-28
IL42998A0 (en) 1973-11-28
DD108457A5 (en) 1974-09-20
CH590197A5 (en) 1977-07-29

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