ES416221A1 - Procedimiento para la preparacion de nuevos derivados de difenilmetano farmacologicamente activos. - Google Patents
Procedimiento para la preparacion de nuevos derivados de difenilmetano farmacologicamente activos.Info
- Publication number
- ES416221A1 ES416221A1 ES416221A ES416221A ES416221A1 ES 416221 A1 ES416221 A1 ES 416221A1 ES 416221 A ES416221 A ES 416221A ES 416221 A ES416221 A ES 416221A ES 416221 A1 ES416221 A1 ES 416221A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- carbamyl
- lower alkyl
- formula
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- MEMNTOZRKPLXOJ-UHFFFAOYSA-N [5-chloro-2-(hydroxymethyl)phenyl]-phenylmethanol Chemical compound OCC1=CC=C(Cl)C=C1C(O)C1=CC=CC=C1 MEMNTOZRKPLXOJ-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000002252 acyl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- FGTYTUFKXYPTML-UHFFFAOYSA-N 2-benzoylbenzoic acid Chemical compound OC(=O)C1=CC=CC=C1C(=O)C1=CC=CC=C1 FGTYTUFKXYPTML-UHFFFAOYSA-N 0.000 abstract 1
- 229940054021 anxiolytics diphenylmethane derivative Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002009 diols Chemical class 0.000 abstract 1
- CZZYITDELCSZES-UHFFFAOYSA-N diphenylmethane Chemical class C=1C=CC=CC=1CC1=CC=CC=C1 CZZYITDELCSZES-UHFFFAOYSA-N 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
- C07C205/34—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups bound to carbon atoms of six-membered aromatic rings and etherified hydroxy groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
- C07C43/1782—Unsaturated ethers containing hydroxy or O-metal groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2611172 | 1972-06-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES416221A1 true ES416221A1 (es) | 1976-02-16 |
Family
ID=11218653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES416221A Expired ES416221A1 (es) | 1972-06-23 | 1973-06-23 | Procedimiento para la preparacion de nuevos derivados de difenilmetano farmacologicamente activos. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3985811A (OSRAM) |
| JP (1) | JPS4949942A (OSRAM) |
| AR (1) | AR200729A1 (OSRAM) |
| AT (1) | AT329549B (OSRAM) |
| AU (1) | AU5719473A (OSRAM) |
| BE (1) | BE801310A (OSRAM) |
| CH (1) | CH583155A5 (OSRAM) |
| DD (1) | DD104502A5 (OSRAM) |
| DE (1) | DE2331044A1 (OSRAM) |
| ES (1) | ES416221A1 (OSRAM) |
| FR (1) | FR2189070B1 (OSRAM) |
| GB (1) | GB1390487A (OSRAM) |
| HU (1) | HU166591B (OSRAM) |
| IL (1) | IL42303A0 (OSRAM) |
| LU (1) | LU67848A1 (OSRAM) |
| NL (1) | NL7308614A (OSRAM) |
| PH (1) | PH10171A (OSRAM) |
| ZA (1) | ZA733261B (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU189210B (en) * | 1982-12-28 | 1986-06-30 | Richter Gedeon Vegyeszeti Gyar Rt,Hu | Process for the production of new carbamates of antilipaemic effect, as well as therapeutic preparations containing them |
| US4822796A (en) * | 1987-06-01 | 1989-04-18 | Helsley Grover C | 1-((Phenothiazin-10-yl)alkyl)-alpha-phenyl-4-piperidinemethanols and pharmaceutical use |
| ITFI20030202A1 (it) * | 2003-07-28 | 2005-01-29 | Synteco Spa | Processo per la preparazione di derivati del |
| RU2614142C1 (ru) * | 2016-01-14 | 2017-03-23 | Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский Томский политехнический университет" | Способ получения мета-хлорбензгидриламина - полупродукта в синтезе противосудорожного препарата галодиф |
-
1973
- 1973-05-15 GB GB2306873A patent/GB1390487A/en not_active Expired
- 1973-05-15 ZA ZA733261A patent/ZA733261B/xx unknown
- 1973-05-18 IL IL42303A patent/IL42303A0/xx unknown
- 1973-05-23 US US05/363,226 patent/US3985811A/en not_active Expired - Lifetime
- 1973-06-15 CH CH872973A patent/CH583155A5/xx not_active IP Right Cessation
- 1973-06-19 DE DE2331044A patent/DE2331044A1/de active Pending
- 1973-06-20 AT AT541973A patent/AT329549B/de not_active IP Right Cessation
- 1973-06-20 PH PH14754*A patent/PH10171A/en unknown
- 1973-06-21 LU LU67848A patent/LU67848A1/xx unknown
- 1973-06-21 AU AU57194/73A patent/AU5719473A/en not_active Expired
- 1973-06-21 NL NL7308614A patent/NL7308614A/xx unknown
- 1973-06-22 BE BE132605A patent/BE801310A/xx unknown
- 1973-06-22 DD DD171813A patent/DD104502A5/xx unknown
- 1973-06-22 FR FR7322906A patent/FR2189070B1/fr not_active Expired
- 1973-06-22 JP JP48070678A patent/JPS4949942A/ja active Pending
- 1973-06-22 HU HULE711A patent/HU166591B/hu unknown
- 1973-06-22 AR AR248680A patent/AR200729A1/es active
- 1973-06-23 ES ES416221A patent/ES416221A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE801310A (fr) | 1973-10-15 |
| JPS4949942A (OSRAM) | 1974-05-15 |
| AR200729A1 (es) | 1974-12-13 |
| AT329549B (de) | 1976-05-10 |
| HU166591B (OSRAM) | 1975-04-28 |
| AU5719473A (en) | 1975-01-09 |
| IL42303A0 (en) | 1973-07-30 |
| DD104502A5 (OSRAM) | 1974-03-12 |
| FR2189070B1 (OSRAM) | 1976-12-31 |
| FR2189070A1 (OSRAM) | 1974-01-25 |
| DE2331044A1 (de) | 1974-01-10 |
| ATA541973A (de) | 1975-08-15 |
| CH583155A5 (OSRAM) | 1976-12-31 |
| LU67848A1 (OSRAM) | 1973-08-30 |
| ZA733261B (en) | 1974-04-24 |
| NL7308614A (OSRAM) | 1973-12-27 |
| PH10171A (en) | 1976-09-15 |
| US3985811A (en) | 1976-10-12 |
| GB1390487A (en) | 1975-04-16 |
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