ES415034A1 - Water-soluble derivatives of tetracycline antibiotics - Google Patents

Water-soluble derivatives of tetracycline antibiotics

Info

Publication number
ES415034A1
ES415034A1 ES415034A ES415034A ES415034A1 ES 415034 A1 ES415034 A1 ES 415034A1 ES 415034 A ES415034 A ES 415034A ES 415034 A ES415034 A ES 415034A ES 415034 A1 ES415034 A1 ES 415034A1
Authority
ES
Spain
Prior art keywords
glycyrrhizic acid
water
tetracycline antibiotics
soluble derivatives
tetracycline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES415034A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHIMICO FARMACEUTICO DR BLASIN
Original Assignee
CHIMICO FARMACEUTICO DR BLASIN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CHIMICO FARMACEUTICO DR BLASIN filed Critical CHIMICO FARMACEUTICO DR BLASIN
Publication of ES415034A1 publication Critical patent/ES415034A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/256—Polyterpene radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

Procedure for preparing aqueous soluble salts of glycyrrhizic acid and complex derivatives of tetracycline antibiotics selected from the group consisting of metacycline, doxycycline, demitylchlorotetracycline, sancycline and minocycline, characterized in that the glycyrrhizic acid is reacted with the desired tetracycline antibiotic in a molar ratio glycyrrhizic acid: tetracycline antibiotic in the presence of an appropriate inorganic or organic base and the resulting salts or complex addition derivatives are recovered by lyophilization or by filtration. (Machine-translation by Google Translate, not legally binding)
ES415034A 1972-05-24 1973-05-23 Water-soluble derivatives of tetracycline antibiotics Expired ES415034A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25640672A 1972-05-24 1972-05-24

Publications (1)

Publication Number Publication Date
ES415034A1 true ES415034A1 (en) 1976-05-16

Family

ID=22972116

Family Applications (1)

Application Number Title Priority Date Filing Date
ES415034A Expired ES415034A1 (en) 1972-05-24 1973-05-23 Water-soluble derivatives of tetracycline antibiotics

Country Status (13)

Country Link
JP (1) JPS4941519A (en)
AT (1) AT326820B (en)
AU (1) AU5621973A (en)
BE (1) BE799914A (en)
CA (1) CA983023A (en)
DE (1) DE2326106A1 (en)
ES (1) ES415034A1 (en)
FR (1) FR2185393A1 (en)
GB (1) GB1403647A (en)
HU (1) HU167706B (en)
NL (1) NL7306746A (en)
SU (1) SU499803A3 (en)
ZA (1) ZA733521B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5215699A (en) * 1975-09-29 1977-02-05 Toray Industries Permanent sweat absorbing finish of polyester synthetic knitt fabric
US4806529A (en) * 1982-11-18 1989-02-21 Trustees Of Tufts College, Tufts University Tetracycline activity enhancement
JPS59228084A (en) * 1983-06-09 1984-12-21 日本合成化学工業株式会社 Warp yarn size agent for hydrophobic fiber

Also Published As

Publication number Publication date
SU499803A3 (en) 1976-01-15
CA983023A (en) 1976-02-03
HU167706B (en) 1975-12-25
FR2185393A1 (en) 1974-01-04
ZA733521B (en) 1974-04-24
AU5621973A (en) 1974-11-28
BE799914A (en) 1973-09-17
AT326820B (en) 1975-12-29
NL7306746A (en) 1973-11-27
JPS4941519A (en) 1974-04-18
GB1403647A (en) 1975-08-28
ATA431773A (en) 1975-03-15
DE2326106A1 (en) 1973-12-06

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