ES413489A1 - Certain pyridine carboxylic acid esters - Google Patents

Certain pyridine carboxylic acid esters

Info

Publication number
ES413489A1
ES413489A1 ES413489A ES413489A ES413489A1 ES 413489 A1 ES413489 A1 ES 413489A1 ES 413489 A ES413489 A ES 413489A ES 413489 A ES413489 A ES 413489A ES 413489 A1 ES413489 A1 ES 413489A1
Authority
ES
Spain
Prior art keywords
formula
racemates
carboxylic acid
lower alkyl
separated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES413489A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH521372A external-priority patent/CH571497A5/en
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES413489A1 publication Critical patent/ES413489A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
    • C07C245/12—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom
    • C07C245/14—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom having diazo groups bound to acyclic carbon atoms of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/227—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
    • C07C49/237—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedure for obtaining new esters of pyridinecarboxylic acid of formula I **(See formula)** where R1 represents 1-cycloalkenyl, R2 represents hydrogen, lower alkyl, halogen or trifluoromethyl, R3 represents hydrogen, lower alkyl or cycloalkyl, A represents a direct bond or methylene or -AO- means -CO-CH2-O- and Py means pyridyl, characterized in that an alcohol, optionally functionally modified, capable of reaction, of formula II **(See formula)** in which R1, R2, R3 and A have the meanings indicated above, it is reacted with a carboxylic acid of formula III HO-CO-Py (III) or a functional acid derivative thereof, where Py has the meaning set forth above, and, if desired, within the scope of the final product definition, substituents, and/or mixtures of racemates obtained, are introduced, modified or dissociated. they are separated into the pure racemates and/or the racemates obtained are separated into the optical antipodes, and/or the salts obtained are transformed into the free compounds or the free compounds obtained in their salts. (Machine-translation by Google Translate, not legally binding)
ES413489A 1972-04-10 1973-04-09 Certain pyridine carboxylic acid esters Expired ES413489A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH521372A CH571497A5 (en) 1972-04-10 1972-04-10 Pyridine-carboxylic acid aralkyl esters - anti-inflammatories, anti-phlogistics and peripheral analgesics
CH292073 1973-02-28

Publications (1)

Publication Number Publication Date
ES413489A1 true ES413489A1 (en) 1976-05-01

Family

ID=25691731

Family Applications (1)

Application Number Title Priority Date Filing Date
ES413489A Expired ES413489A1 (en) 1972-04-10 1973-04-09 Certain pyridine carboxylic acid esters

Country Status (13)

Country Link
US (1) US3876648A (en)
JP (1) JPS497285A (en)
AR (1) AR197495A1 (en)
CA (1) CA998676A (en)
DD (1) DD105217A5 (en)
DE (1) DE2316851A1 (en)
ES (1) ES413489A1 (en)
FR (1) FR2182936B1 (en)
GB (1) GB1393515A (en)
IE (1) IE37506B1 (en)
IL (1) IL41932A (en)
NL (1) NL7305007A (en)
SE (1) SE385883B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2330838A1 (en) * 1973-06-16 1975-01-09 Thomae Gmbh Dr K NEW CARBONIC ACID ESTERS OF 3- (4-BIPHENYLYL) -1-BUTANOLS AND 3- (4-BIPHENYLYL) 2-BUTEN-1-OLEN
JPS5344572A (en) * 1976-09-30 1978-04-21 Meiji Seika Kaisha Ltd 5-alkoxy-picolic acid, its preparation and hypotensives containing the same
JPS5836660B2 (en) * 1978-12-13 1983-08-10 財団法人特殊無機材料研究所 Method for producing high-strength, heat-resistant, dispersion-strengthened metal materials with excellent ductility
FR2466458A1 (en) * 1979-09-27 1981-04-10 Mathieu Andre NEW EUGENOL-DERIVED MEDICINAL PRODUCTS
US4327218A (en) * 1979-10-01 1982-04-27 Stauffer Chemical Company N-Aryl, 2-phenoxy nicotinamide compounds and the herbicidal use thereof
ITMI20010395A1 (en) 2001-02-27 2002-08-27 Dompe Spa OMEGA-AMINO ALKYLAMIDS OF R-2-ARYL-PROPIONIC ACIDS AS INHIBITORS OF CHEMOTAXIS OF POLYMORPHONUCLEATED AND MONONUCLEATE CELLS
WO2004052830A1 (en) * 2002-12-10 2004-06-24 Dompe S.P.A. Chiral arylketones in the treatement of neutrophil-dependent inflammatory deseases
AR092355A1 (en) * 2012-07-24 2015-04-15 Dow Agrosciences Llc FLUOROPICOLINOYL FLUORURES AND PROCESSES FOR THEIR PREPARATION

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3557129A (en) * 1968-05-14 1971-01-19 Ortho Pharma Corp Certain pyridoyl and furoyl esters of 2-(lower alkyl) - 3 - (lower alkayl)-4-aryl-3 or 4-cyclohexene carbinols
DE2222791A1 (en) * 1971-05-19 1972-12-07 Ciba Geigy Ag New pyridine acid derivatives and processes for their preparation

Also Published As

Publication number Publication date
GB1393515A (en) 1975-05-07
AR197495A1 (en) 1974-04-15
CA998676A (en) 1976-10-19
FR2182936B1 (en) 1975-10-31
IE37506L (en) 1973-10-10
IL41932A (en) 1976-08-31
FR2182936A1 (en) 1973-12-14
DE2316851A1 (en) 1973-10-25
NL7305007A (en) 1973-10-12
JPS497285A (en) 1974-01-22
DD105217A5 (en) 1974-04-12
SE385883B (en) 1976-07-26
US3876648A (en) 1975-04-08
IE37506B1 (en) 1977-08-03

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