ES412609A1 - Procedimiento para la obtencion de bis (3,4,5-trimetoxi- benzoato) de piridin-2,6-dimetanol. - Google Patents
Procedimiento para la obtencion de bis (3,4,5-trimetoxi- benzoato) de piridin-2,6-dimetanol.Info
- Publication number
- ES412609A1 ES412609A1 ES412609A ES412609A ES412609A1 ES 412609 A1 ES412609 A1 ES 412609A1 ES 412609 A ES412609 A ES 412609A ES 412609 A ES412609 A ES 412609A ES 412609 A1 ES412609 A1 ES 412609A1
- Authority
- ES
- Spain
- Prior art keywords
- dimethanol
- pyridine
- trimethoxybenzoate
- reaction
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WWFMINHWJYHXHF-UHFFFAOYSA-N [6-(hydroxymethyl)pyridin-2-yl]methanol Chemical compound OCC1=CC=CC(CO)=N1 WWFMINHWJYHXHF-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- SJSOFNCYXJUNBT-UHFFFAOYSA-N 3,4,5-trimethoxybenzoic acid Chemical compound COC1=CC(C(O)=O)=CC(OC)=C1OC SJSOFNCYXJUNBT-UHFFFAOYSA-N 0.000 abstract 1
- BUHYMJLFRZAFBF-UHFFFAOYSA-N 3,4,5-trimethoxybenzoyl chloride Chemical compound COC1=CC(C(Cl)=O)=CC(OC)=C1OC BUHYMJLFRZAFBF-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000012043 crude product Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 150000003512 tertiary amines Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES412609A ES412609A1 (es) | 1973-03-14 | 1973-03-14 | Procedimiento para la obtencion de bis (3,4,5-trimetoxi- benzoato) de piridin-2,6-dimetanol. |
| AT169174A AT332403B (de) | 1973-03-14 | 1974-03-01 | Verfahren zur herstellung des neuen bis- (3,4,5-trimethoxybenzoats) von pyridin -2,6-dimethanol |
| IE00473/74A IE38974B1 (en) | 1973-03-14 | 1974-03-07 | Method of preparing bis(3,4-5-trimethoxybenzoate) of pyridine-2,6-dimethanol |
| BE141864A BE812127A (fr) | 1973-03-14 | 1974-03-11 | Bis-(trimethoxy-3 |
| SE7403264A SE401828B (sv) | 1973-03-14 | 1974-03-12 | Forfarande for framstellning av bis(3,4,5-trimetoxibensoat)-estern av pyridin-2,6-dimetanol |
| DK137674A DK145857C (da) | 1973-03-14 | 1974-03-13 | Analogifremgangsmaade til fremstilling af di-3,4,5-trimethoxybenzoesyreesteren af pyridin-2,6-dimethanol |
| CH349374A CH581109A5 (enrdf_load_stackoverflow) | 1973-03-14 | 1974-03-13 | |
| CA194,937A CA972375A (en) | 1973-03-14 | 1974-03-13 | Process for obtaining bis(3,4,5-trimethoxybenzoate) of pyridine-2,6-dimethanol |
| NO740885A NO144148C (no) | 1973-03-14 | 1974-03-13 | Analogifremgangsmaate ved fremstilling av terapeutisk aktivt bis(3,4,5-trimethoxy-benzoat) av pyridin-2,6-dimethanol |
| DE2411902A DE2411902A1 (de) | 1973-03-14 | 1974-03-13 | Pyridin-2,6-dimethanol-bis-(3,4,5- trimethoxybenzoat) und verfahren zu seiner herstellung |
| JP2863974A JPS5716103B2 (enrdf_load_stackoverflow) | 1973-03-14 | 1974-03-14 | |
| NLAANVRAGE7403436,A NL183648C (nl) | 1973-03-14 | 1974-03-14 | Werkwijze voor de bereiding van een hydroxymethylpyridinederivaat bevattend geneesmiddel met cardiovasculaire werking, alsmede voor de daarvoor geschikte verbinding. |
| FR7409586A FR2221149B1 (enrdf_load_stackoverflow) | 1973-03-14 | 1974-03-14 | |
| GB1142974A GB1401608A (en) | 1973-03-14 | 1974-03-14 | Method of preparing bis-3,4,5-trimethoxybenzoate of pyridine -2,6-dimethanol |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES412609A ES412609A1 (es) | 1973-03-14 | 1973-03-14 | Procedimiento para la obtencion de bis (3,4,5-trimetoxi- benzoato) de piridin-2,6-dimetanol. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES412609A1 true ES412609A1 (es) | 1976-01-01 |
Family
ID=8463660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES412609A Expired ES412609A1 (es) | 1973-03-14 | 1973-03-14 | Procedimiento para la obtencion de bis (3,4,5-trimetoxi- benzoato) de piridin-2,6-dimetanol. |
Country Status (14)
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE322214B (enrdf_load_stackoverflow) * | 1965-06-28 | 1970-04-06 | Bofors Ab | |
| US3432510A (en) * | 1966-07-18 | 1969-03-11 | Searle & Co | Pyridinecarboxylic acid esters of pyridinedimethanols |
-
1973
- 1973-03-14 ES ES412609A patent/ES412609A1/es not_active Expired
-
1974
- 1974-03-01 AT AT169174A patent/AT332403B/de not_active IP Right Cessation
- 1974-03-07 IE IE00473/74A patent/IE38974B1/xx unknown
- 1974-03-11 BE BE141864A patent/BE812127A/xx not_active IP Right Cessation
- 1974-03-12 SE SE7403264A patent/SE401828B/xx not_active IP Right Cessation
- 1974-03-13 DK DK137674A patent/DK145857C/da not_active IP Right Cessation
- 1974-03-13 CH CH349374A patent/CH581109A5/xx not_active IP Right Cessation
- 1974-03-13 NO NO740885A patent/NO144148C/no unknown
- 1974-03-13 CA CA194,937A patent/CA972375A/en not_active Expired
- 1974-03-13 DE DE2411902A patent/DE2411902A1/de active Granted
- 1974-03-14 GB GB1142974A patent/GB1401608A/en not_active Expired
- 1974-03-14 FR FR7409586A patent/FR2221149B1/fr not_active Expired
- 1974-03-14 JP JP2863974A patent/JPS5716103B2/ja not_active Expired
- 1974-03-14 NL NLAANVRAGE7403436,A patent/NL183648C/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BE812127A (fr) | 1974-07-01 |
| FR2221149B1 (enrdf_load_stackoverflow) | 1977-11-04 |
| NO144148B (no) | 1981-03-23 |
| IE38974B1 (en) | 1978-07-05 |
| NO740885L (no) | 1974-09-17 |
| DE2411902A1 (de) | 1974-09-19 |
| NL183648B (nl) | 1988-07-18 |
| CH581109A5 (enrdf_load_stackoverflow) | 1976-10-29 |
| ATA169174A (de) | 1976-01-15 |
| NL183648C (nl) | 1988-12-16 |
| SE401828B (sv) | 1978-05-29 |
| DK145857B (da) | 1983-03-21 |
| DE2411902C2 (enrdf_load_stackoverflow) | 1987-07-09 |
| DK145857C (da) | 1983-09-05 |
| NL7403436A (enrdf_load_stackoverflow) | 1974-09-17 |
| AT332403B (de) | 1976-09-27 |
| JPS5029569A (enrdf_load_stackoverflow) | 1975-03-25 |
| JPS5716103B2 (enrdf_load_stackoverflow) | 1982-04-02 |
| NO144148C (no) | 1981-07-01 |
| FR2221149A1 (enrdf_load_stackoverflow) | 1974-10-11 |
| CA972375A (en) | 1975-08-05 |
| GB1401608A (en) | 1975-07-16 |
| IE38974L (en) | 1974-09-14 |
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