ES410863A1 - Un procedimiento para preparar un compuesto de 1,4-benzo- diazepina sustituido en la posicion 1. - Google Patents
Un procedimiento para preparar un compuesto de 1,4-benzo- diazepina sustituido en la posicion 1.Info
- Publication number
- ES410863A1 ES410863A1 ES410863A ES410863A ES410863A1 ES 410863 A1 ES410863 A1 ES 410863A1 ES 410863 A ES410863 A ES 410863A ES 410863 A ES410863 A ES 410863A ES 410863 A1 ES410863 A1 ES 410863A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- chlorine
- compound
- substituted
- defined above
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000003310 benzodiazepinyl group Chemical class N1N=C(C=CC2=C1C=CC=C2)* 0.000 title 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 4
- 239000000460 chlorine Chemical group 0.000 abstract 4
- 229910052801 chlorine Chemical group 0.000 abstract 4
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- -1 1-substituted 1,4-benzodiazepine compound Chemical class 0.000 abstract 2
- 239000002253 acid Chemical group 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 125000005544 phthalimido group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- NWZSZGALRFJKBT-KNIFDHDWSA-N (2s)-2,6-diaminohexanoic acid;(2s)-2-hydroxybutanedioic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O.NCCCC[C@H](N)C(O)=O NWZSZGALRFJKBT-KNIFDHDWSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000000219 ethylidene group Chemical group [H]C(=[*])C([H])([H])[H] 0.000 abstract 1
- IKDUDTNKRLTJSI-UHFFFAOYSA-N hydrazine monohydrate Substances O.NN IKDUDTNKRLTJSI-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1169472A JPS5629668B2 (enrdf_load_stackoverflow) | 1972-01-31 | 1972-01-31 | |
| JP2781972A JPS5634592B2 (enrdf_load_stackoverflow) | 1972-03-17 | 1972-03-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES410863A1 true ES410863A1 (es) | 1976-04-16 |
Family
ID=26347177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES410863A Expired ES410863A1 (es) | 1972-01-31 | 1973-01-22 | Un procedimiento para preparar un compuesto de 1,4-benzo- diazepina sustituido en la posicion 1. |
Country Status (10)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2450825A1 (fr) * | 1979-03-09 | 1980-10-03 | Synthelabo | Derives de benzodiazepine et leur application en therapeutique |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2141904B2 (de) * | 1970-08-31 | 1976-07-01 | Sumitomo Chemical Co., Ltd., Osaka (Japan) | L- eckige klammer auf beta- (alpha'-tetrahydropyranyloxy)-aethyl eckige klammer zu -1,3-dihydro-5- phenyl-2h-1,4-benzodiazepin-2-one |
-
0
- BE BE794536D patent/BE794536A/xx unknown
-
1973
- 1973-01-18 GB GB258973A patent/GB1412198A/en not_active Expired
- 1973-01-22 ES ES410863A patent/ES410863A1/es not_active Expired
- 1973-01-25 NL NL7301091A patent/NL7301091A/xx not_active Application Discontinuation
- 1973-01-27 DE DE19732303965 patent/DE2303965A1/de active Pending
- 1973-01-29 SE SE7301213A patent/SE402587B/xx unknown
- 1973-01-29 CA CA162,320A patent/CA1010034A/en not_active Expired
- 1973-01-29 FR FR7303069A patent/FR2181697B1/fr not_active Expired
- 1973-01-30 CH CH362176A patent/CH580606A5/xx not_active IP Right Cessation
- 1973-01-30 CH CH127473A patent/CH580089A5/xx not_active IP Right Cessation
- 1973-01-30 AR AR24635073A patent/AR195591A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| CH580606A5 (enrdf_load_stackoverflow) | 1976-10-15 |
| DE2303965A1 (de) | 1973-08-09 |
| SE402587B (sv) | 1978-07-10 |
| FR2181697B1 (enrdf_load_stackoverflow) | 1976-10-22 |
| NL7301091A (enrdf_load_stackoverflow) | 1973-08-02 |
| CH580089A5 (enrdf_load_stackoverflow) | 1976-09-30 |
| FR2181697A1 (enrdf_load_stackoverflow) | 1973-12-07 |
| GB1412198A (en) | 1975-10-29 |
| BE794536A (fr) | 1973-07-25 |
| AR195591A1 (es) | 1973-10-23 |
| CA1010034A (en) | 1977-05-10 |
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