ES410435A1 - Immunostimulant agent compositions thereof and methods for their preparation - Google Patents

Immunostimulant agent compositions thereof and methods for their preparation

Info

Publication number
ES410435A1
ES410435A1 ES410435A ES410435A ES410435A1 ES 410435 A1 ES410435 A1 ES 410435A1 ES 410435 A ES410435 A ES 410435A ES 410435 A ES410435 A ES 410435A ES 410435 A1 ES410435 A1 ES 410435A1
Authority
ES
Spain
Prior art keywords
cells
chloroform
preparation
bacteria
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES410435A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur de Lille
Original Assignee
Institut Pasteur de Lille
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur de Lille filed Critical Institut Pasteur de Lille
Publication of ES410435A1 publication Critical patent/ES410435A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/062—Ascomycota
    • A61K36/064—Saccharomycetales, e.g. baker's yeast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/13—Tumour cells, irrespective of tissue of origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/26—Lymph; Lymph nodes; Thymus; Spleen; Splenocytes; Thymocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588—Adjuvants of undefined constitution
    • A61K2039/55594—Adjuvants of undefined constitution from bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Developmental Biology & Embryology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Procedure for the preparation of immunostimulants and, more particularly, for the extraction of an immunostimulatory agent, from spleen cells of animal origin, Ehrlich ascite cells or bacteria or Bacillus subtilis and Saccharomyces cerevisiae cells, characterized in that make a suspension of these cells or these bacteria with a mixture of solvents that contains a halogenated hydrocarbon, such as chloroform, and an alcohol, such as methanol, in that insoluble fractions are separated, in particular by centrifugation, by that the liquid fraction is evaporated under reduced pressure and at a reduced temperature and that the solid residue is taken up again in chloroform and the chloroform solution containing the mentioned immunostimulatory agent is collected by filtration. (Machine-translation by Google Translate, not legally binding)
ES410435A 1971-12-24 1972-12-23 Immunostimulant agent compositions thereof and methods for their preparation Expired ES410435A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7146520A FR2164510B1 (en) 1971-12-24 1971-12-24

Publications (1)

Publication Number Publication Date
ES410435A1 true ES410435A1 (en) 1976-01-01

Family

ID=9088030

Family Applications (1)

Application Number Title Priority Date Filing Date
ES410435A Expired ES410435A1 (en) 1971-12-24 1972-12-23 Immunostimulant agent compositions thereof and methods for their preparation

Country Status (15)

Country Link
JP (1) JPS4868729A (en)
AR (1) AR195897A1 (en)
BE (1) BE793260A (en)
CA (1) CA991543A (en)
CS (1) CS190380B2 (en)
DE (1) DE2262427C3 (en)
DK (1) DK137887B (en)
ES (1) ES410435A1 (en)
FR (1) FR2164510B1 (en)
GB (1) GB1419969A (en)
IL (1) IL41120A (en)
NL (1) NL7217588A (en)
PL (1) PL89687B1 (en)
SU (1) SU592333A3 (en)
ZA (1) ZA728959B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2287901A1 (en) * 1974-10-14 1976-05-14 Pasteur Institut IMMUNOSTIMULANT MEDICINAL PRODUCT CONTAINING OSE DERIVATIVE OR PHOSPHORYL POLYOSE
JPS5835121A (en) * 1981-08-20 1983-03-01 ビラス・ヴィー・リクハイト Antigen consisting of immunostimulant aid and use in immunological therapy
CA1225592A (en) * 1983-08-26 1987-08-18 Ribi Immunochem Research Inc. Refined detoxified endotoxin
IT1186793B (en) * 1985-11-26 1987-12-16 Sibar Srl FRACTION OBTAINED FROM LISTERIA MONOCYTOGENES WITH THERAPEUTIC ACTIVITY, PROCEDURE FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT
JPH02131433A (en) * 1988-11-11 1990-05-21 Nisshin Flour Milling Co Ltd Preventive and therapeutic agent for nonspecific infectious diseases
EP3150323B1 (en) 2015-09-30 2020-11-18 Kabushiki Kaisha Toshiba Laser processing apparatus, laser processing method and distance measurement method
CN111642460B (en) * 2020-06-23 2022-06-28 山西省中医药研究院（山西省中医院） Construction method of pineal body injury rat model

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU57091A1 (en) * 1968-10-15 1970-04-16

Also Published As

Publication number Publication date
AR195897A1 (en) 1973-11-15
CS190380B2 (en) 1979-05-31
DE2262427A1 (en) 1973-07-12
FR2164510B1 (en) 1975-02-07
SU592333A3 (en) 1978-02-05
IL41120A0 (en) 1973-02-28
CA991543A (en) 1976-06-22
DK137887B (en) 1978-05-29
DE2262427B2 (en) 1979-08-09
GB1419969A (en) 1975-12-31
FR2164510A1 (en) 1973-08-03
PL89687B1 (en) 1976-12-31
IL41120A (en) 1975-12-31
NL7217588A (en) 1973-06-26
JPS4868729A (en) 1973-09-19
BE793260A (en) 1973-06-22
ZA728959B (en) 1973-09-26
DE2262427C3 (en) 1980-04-24
DK137887C (en) 1978-10-16

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