ES409589A1 - A procedure for the preparation of cefalosporine compounds. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the preparation of cefalosporine compounds. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES409589A1 ES409589A1 ES409589A ES409589A ES409589A1 ES 409589 A1 ES409589 A1 ES 409589A1 ES 409589 A ES409589 A ES 409589A ES 409589 A ES409589 A ES 409589A ES 409589 A1 ES409589 A1 ES 409589A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compound
- defined above
- procedure
- see formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B21/00—Nitrogen; Compounds thereof
- C01B21/08—Hydrazoic acid; Azides; Halogen azides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Abstract
A procedure for the preparation of cephalosporin compounds of the formula: **(See formula)** where R is phenyl or a 5-membered ring containing 1 or 2 heteroatoms, the latter being sulfur, oxygen or nitrogen; A is hydrogen, lower alkanoyl oxy, carbamoyloxy, thiocarbamoyloxy, N-lower alkyl carbamoyloxy, N-lower alkyl thiocarbamoyloxy, N, N-dialkyl lower carbamoyloxy, N, N-dialkyl lower thiocarbamoyloxy, pyridinium, alkyl pyridinium, halopyridinium or aminopyridinium; and M is sodium, potassium or hydrogen; whose procedure consists of a) heating a compound of formula: **(See formula)** where R, M and A are those defined above, at a temperature between 60 and 100ºC or b) reacting a compound of formula: **(See formula)** where R, M and A are as defined above, with 2-nitroso-2-methylpropane, followed by heating at 80-90ºC for 1 or 2 hours in hydroquinone; or c) reducing a compound of formula: **(See formula)** where R, M and A are as defined above, with zinc powder in an aqueous solution of acetic acid at room temperature; or d) reacting a compound of formula: **(See formula)** where R, A or M are as defined above, with hydroquinone and then with sodium hydride and then heating. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20894171A | 1971-12-16 | 1971-12-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES409589A1 true ES409589A1 (en) | 1976-01-01 |
Family
ID=22776684
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES409589A Expired ES409589A1 (en) | 1971-12-16 | 1972-12-13 | A procedure for the preparation of cefalosporine compounds. (Machine-translation by Google Translate, not legally binding) |
Country Status (6)
Country | Link |
---|---|
JP (1) | JPS4867293A (en) |
CA (1) | CA992956A (en) |
CH (1) | CH581141A5 (en) |
DD (1) | DD101680A5 (en) |
ES (1) | ES409589A1 (en) |
NL (1) | NL7216268A (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4165429A (en) * | 1976-06-28 | 1979-08-21 | Yamanouchi Pharmaceutical Co., Ltd. | 7α-METHOXY-CEPHALOSPORANIC ACID DERIVATIVES |
ATE11540T1 (en) * | 1980-10-15 | 1985-02-15 | F. Hoffmann-La Roche & Co. Aktiengesellschaft | PROCESS FOR THE PREPARATION OF 6AMINOPENICILLANS|UREDERIVATIVES AND INTERMEDIATE PRODUCTS THEREOF. |
-
1972
- 1972-11-30 NL NL7216268A patent/NL7216268A/xx not_active Application Discontinuation
- 1972-12-07 DD DD16737372A patent/DD101680A5/xx unknown
- 1972-12-08 CA CA158,810A patent/CA992956A/en not_active Expired
- 1972-12-13 CH CH1813272A patent/CH581141A5/en not_active IP Right Cessation
- 1972-12-13 ES ES409589A patent/ES409589A1/en not_active Expired
- 1972-12-15 JP JP12533672A patent/JPS4867293A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CA992956A (en) | 1976-07-13 |
NL7216268A (en) | 1973-06-19 |
CH581141A5 (en) | 1976-10-29 |
JPS4867293A (en) | 1973-09-13 |
DD101680A5 (en) | 1973-11-12 |
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