ES408925A1 - A procedure for the preparation of new bencimidazolil-2-aminoimidazolines. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of new bencimidazolil-2-aminoimidazolines. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES408925A1
ES408925A1 ES408925A ES408925A ES408925A1 ES 408925 A1 ES408925 A1 ES 408925A1 ES 408925 A ES408925 A ES 408925A ES 408925 A ES408925 A ES 408925A ES 408925 A1 ES408925 A1 ES 408925A1
Authority
ES
Spain
Prior art keywords
amino
hydrogen
formula
aminoimidazolines
translation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES408925A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB5449871A external-priority patent/GB1410017A/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES408925A1 publication Critical patent/ES408925A1/en
Expired legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

A procedure for the preparation of new benzimidazolyl -2-aminoimidazolines of formula (I): **(See formula)** and salts and solvates thereof, where R is hydrogen or lower acyl; R1 and R2 are each hydrogen or lower alkyl; R3 is hydrogen or a lower hydrocarbon; R4, R5, R6 and R7, which may be the same or different, are each selected from halogen, hydrogen, nitro, nitrile, lower aliphatic hydrocarbon, halogenated lower aliphatic hydrocarbon, sulfonic acid, lower esterified carboxyl, carboxylic acid, hydroxyl, hydroxyl. lower acylated, amino, dialkyl (lower) amino, lower acylated amino, amino (lower) oxycarbonylated amino or a lower hydrocarbon hydroxyl group, the process of which comprises the reaction of a compound of formula (III): **(See formula)** where R11 is a nitrile group or an amidino group, with a diamine of formula (IV): NH2 - CHR2- CHR3-NH2 (IV) and then, if desired, variation of the groups R4, R5, R6 and R7 in a known manner or acylation of a nitrogen atom of the imidazoline ring. (Machine-translation by Google Translate, not legally binding)
ES408925A 1971-11-24 1972-11-23 A procedure for the preparation of new bencimidazolil-2-aminoimidazolines. (Machine-translation by Google Translate, not legally binding) Expired ES408925A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5449871A GB1410017A (en) 1971-11-24 1971-11-24 Benzimidazole derivatives

Publications (1)

Publication Number Publication Date
ES408925A1 true ES408925A1 (en) 1975-10-16

Family

ID=10471207

Family Applications (1)

Application Number Title Priority Date Filing Date
ES408925A Expired ES408925A1 (en) 1971-11-24 1972-11-23 A procedure for the preparation of new bencimidazolil-2-aminoimidazolines. (Machine-translation by Google Translate, not legally binding)

Country Status (4)

Country Link
DK (1) DK132432C (en)
ES (1) ES408925A1 (en)
IL (1) IL40755A0 (en)
ZA (1) ZA728349B (en)

Also Published As

Publication number Publication date
ZA728349B (en) 1973-08-29
DK132432B (en) 1975-12-08
IL40755A0 (en) 1973-01-30
DK132432C (en) 1976-05-10

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