ES406047A1 - Procedure for the production of coronary agents in breastfeed gelatin capsules (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the production of coronary agents in breastfeed gelatin capsules (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES406047A1
ES406047A1 ES406047A ES406047A ES406047A1 ES 406047 A1 ES406047 A1 ES 406047A1 ES 406047 A ES406047 A ES 406047A ES 406047 A ES406047 A ES 406047A ES 406047 A1 ES406047 A1 ES 406047A1
Authority
ES
Spain
Prior art keywords
weight
gelatin capsules
procedure
parts
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES406047A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25761638&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES406047(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE19722209526 external-priority patent/DE2209526C3/en
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES406047A1 publication Critical patent/ES406047A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S206/00—Special receptacle or package
    • Y10S206/828—Medicinal content

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Procedure for the production of coronary agents in gelatin capsules breakable by bite, containing 4- (2 "-nitrophenyl) -2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine and a polyalkylene glycol, of administration per you; characterized in that in a first step, a coronary agent with rapid perlingually resorbable action is prepared, mixing, under yellow sodium light, in arbitrary sequence, (a) 1 part by weight of 4- (2''nitro-phenyl) -2, 6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine, (b) 6 to 50, preferably 15 to 35, parts by weight of polyalkylene glycol with 2-3 carbon atoms in the alkylene radicals and with an average molecular weight from 200 to 600, 1 to 10 parts by weight of lower alcohols with 1 to 3 hydroxyl groups, especially glycerin; (d) 1 to 10 parts by weight of water, and, optionally, subsequent customary auxiliary agents, and in a second step, the solution thus obtained is filled into gelatin capsules containing a dye that absorbs light with wavelength from 280 to 420 nm, especially the food dye gelborange-s (color index 15 985) and opacifying agents, especially titanium dioxide, forming these two-gelatin gelatin capsules by the "rotary-die" procedure ", first in two half bowls that are then welded except for a small opening for the filling of the active substance solution and which, after filling with the solution, are completely sealed by welding. (Machine-translation by Google Translate, not legally binding)
ES406047A 1971-08-24 1972-08-23 Procedure for the production of coronary agents in breastfeed gelatin capsules (Machine-translation by Google Translate, not legally binding) Expired ES406047A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2142316 1971-08-24
DE19722209526 DE2209526C3 (en) 1972-02-29 1972-02-29 Coronary therapeutic agent in the form of gelatine capsules

Publications (1)

Publication Number Publication Date
ES406047A1 true ES406047A1 (en) 1981-08-16

Family

ID=25761638

Family Applications (1)

Application Number Title Priority Date Filing Date
ES406047A Expired ES406047A1 (en) 1971-08-24 1972-08-23 Procedure for the production of coronary agents in breastfeed gelatin capsules (Machine-translation by Google Translate, not legally binding)

Country Status (25)

Country Link
US (1) US3784684A (en)
JP (2) JPS5434048B2 (en)
KR (1) KR780000433B1 (en)
BE (1) BE787951A (en)
BG (1) BG27728A3 (en)
CA (1) CA981582A (en)
CY (1) CY918A (en)
DD (1) DD99729A5 (en)
DK (1) DK130628B (en)
EG (1) EG10633A (en)
ES (1) ES406047A1 (en)
FI (1) FI53922C (en)
FR (1) FR2150848B1 (en)
GB (1) GB1362627A (en)
HK (1) HK44877A (en)
IE (1) IE36891B1 (en)
IL (1) IL40165A (en)
KE (1) KE2756A (en)
LU (1) LU65929A1 (en)
MY (1) MY7800003A (en)
NL (1) NL176836C (en)
NO (1) NO138167C (en)
RO (1) RO88521B (en)
SG (1) SG34877G (en)
SU (1) SU432703A3 (en)

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US4002718A (en) * 1974-10-16 1977-01-11 Arnar-Stone Laboratories, Inc. Gelatin-encapsulated digoxin solutions and method of preparing the same
US4056610A (en) * 1975-04-09 1977-11-01 Minnesota Mining And Manufacturing Company Microcapsule insecticide composition
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SU432703A3 (en) * 1971-08-24 1974-06-15 Фридрих Боссерт, Вульф Фатер, Курт Бауер

Also Published As

Publication number Publication date
DK130628B (en) 1975-03-17
HK44877A (en) 1977-09-09
JPS4828621A (en) 1973-04-16
NO138167C (en) 1978-07-26
SU432703A3 (en) 1974-06-15
DD99729A5 (en) 1973-08-20
US3784684A (en) 1974-01-08
FR2150848A1 (en) 1973-04-13
BG27728A3 (en) 1979-12-12
CA981582A (en) 1976-01-13
JPS5434048B2 (en) 1979-10-24
JPS53121921A (en) 1978-10-24
KE2756A (en) 1977-10-14
RO88521B (en) 1987-05-01
BE787951A (en) 1973-02-26
IL40165A0 (en) 1972-10-29
IE36891L (en) 1973-02-24
IE36891B1 (en) 1977-03-16
RO88521A (en) 1987-04-30
FR2150848B1 (en) 1976-04-16
NL7211565A (en) 1973-02-27
FI53922C (en) 1979-09-07
DK130628C (en) 1975-08-25
NL176836B (en) 1985-01-16
FI53922B (en) 1978-05-31
GB1362627A (en) 1974-08-07
NL176836C (en) 1985-06-17
LU65929A1 (en) 1973-01-15
IL40165A (en) 1975-03-13
EG10633A (en) 1976-08-31
MY7800003A (en) 1978-12-31
NO138167B (en) 1978-04-10
CY918A (en) 1977-12-23
SG34877G (en) 1987-04-03
KR780000433B1 (en) 1978-10-14

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