ES401198A1 - Procedimiento para la obtencion de derivados de fenilalca- nol sustituidos. - Google Patents

Procedimiento para la obtencion de derivados de fenilalca- nol sustituidos.

Info

Publication number
ES401198A1
ES401198A1 ES401198A ES401198A ES401198A1 ES 401198 A1 ES401198 A1 ES 401198A1 ES 401198 A ES401198 A ES 401198A ES 401198 A ES401198 A ES 401198A ES 401198 A1 ES401198 A1 ES 401198A1
Authority
ES
Spain
Prior art keywords
carbon atoms
derivatives
formula
atoms
carbon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES401198A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of ES401198A1 publication Critical patent/ES401198A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/02Preparation by ring-closure or hydrogenation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/42Oxygen atoms attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Procedimiento para la obtención de derivados de fenialcanol sustituidos de fórmula I **fórmula** en la que R1 significa OH, alcoxi con hasta 6 átomos de carbono, cicloalcoxi con hasta 6 átomos de carbono, ariloxi con 6 a 12 átomos de carbono, aralcoxi con 7 a 12 átomos de carbono o aciloxi con hasta 18 átomos de carbono, preferentemente con hasta 6 átomos de carbono, R2 significa H, alquilo con hasta 6 átomos de carbono, cicloalquilo con hasta 6 átomos de carbono, arilo con 6 a 12 átomos de carbono, aralquilo con 7 a 12 átomos de carbono o acilo con hasta 18 átomos de carbono, preferentemente con hasta 6 átomos de carbono, R3 significa H o CH3, R4 significa Cl, Br o CH3 y n significa 2 o 3, así como sus sales de adición de ácido y sus sales amónicas cuaternarias.
ES401198A 1971-03-25 1972-03-25 Procedimiento para la obtencion de derivados de fenilalca- nol sustituidos. Expired ES401198A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19712114420 DE2114420A1 (de) 1971-03-25 1971-03-25 Substituierte Phenylalkanol-Derivate und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
ES401198A1 true ES401198A1 (es) 1975-10-01

Family

ID=5802691

Family Applications (1)

Application Number Title Priority Date Filing Date
ES401198A Expired ES401198A1 (es) 1971-03-25 1972-03-25 Procedimiento para la obtencion de derivados de fenilalca- nol sustituidos.

Country Status (19)

Country Link
US (1) US3770748A (es)
AT (1) AT344169B (es)
AU (1) AU465561B2 (es)
BE (1) BE781212A (es)
BR (1) BR7201760D0 (es)
CA (1) CA980353A (es)
CH (2) CH605739A5 (es)
CS (4) CS168694B2 (es)
DD (1) DD96946A5 (es)
DE (1) DE2114420A1 (es)
DK (1) DK137273C (es)
ES (1) ES401198A1 (es)
FR (1) FR2130659B1 (es)
GB (1) GB1359600A (es)
IL (1) IL38972A (es)
NL (1) NL7203986A (es)
PL (1) PL83328B1 (es)
SE (1) SE374918B (es)
ZA (1) ZA721653B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993763A (en) * 1969-03-18 1976-11-23 Ciba-Geigy Corporation Tertiary aminoacids as anti-inflammatory agents
US3936467A (en) * 1968-03-27 1976-02-03 Ciba-Geigy Corporation Hydroxyalkylenimino-phenyl-acetic acids
US4216326A (en) * 1975-01-20 1980-08-05 Sterling Drug Inc. Intermediates for preparing anti-inflammatory phenyl-lower-alkylamines
US4417052A (en) * 1980-02-15 1983-11-22 Sterling Drug Inc. Phenyl-lower-alkyl piperidines and pyrrolidines
US7064211B2 (en) * 2002-03-22 2006-06-20 Eisai Co., Ltd. Hemiasterlin derivatives and uses thereof
TWI350168B (en) * 2004-05-07 2011-10-11 Incyte Corp Amido compounds and their use as pharmaceuticals
US20060009471A1 (en) * 2004-06-24 2006-01-12 Wenqing Yao Amido compounds and their use as pharmaceuticals
US7687665B2 (en) * 2004-06-24 2010-03-30 Incyte Corporation 2-methylprop anamides and their use as pharmaceuticals
US20060009491A1 (en) * 2004-06-24 2006-01-12 Incyte Corporation Amido compounds and their use as pharmaceuticals
EP1758580A4 (en) * 2004-06-24 2008-01-16 Incyte Corp N-SUBSTITUTED PIPERIDINE AND ITS USE AS A MEDICAMENT
MX2007001540A (es) * 2004-08-10 2007-04-23 Incyte Corp Compuestos amido y sus usos como farmaceuticos.
US20070213311A1 (en) * 2006-03-02 2007-09-13 Yun-Long Li Modulators of 11-beta hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
WO2007103719A2 (en) * 2006-03-03 2007-09-13 Incyte Corporation MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME
JP2009535420A (ja) * 2006-05-01 2009-10-01 インサイト・コーポレイション 11−βヒドロキシルステロイドデヒドロゲナーゼタイプ1のモジュレーターとしてのテトラ置換ウレア
US7838544B2 (en) * 2006-05-17 2010-11-23 Incyte Corporation Heterocyclic inhibitors of 11-β hydroxyl steroid dehydrogenase type 1 and methods of using the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH501618A (de) * 1968-04-29 1971-01-15 Ciba Geigy Ag Verfahren zur Herstellung von einem neuen, substituierten Phenäthylalkohol
DE2013376A1 (de) * 1970-03-20 1971-10-07 Merck Patent Gmbh Substituierte Phenylessigsauren und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
CH588460A5 (es) 1977-06-15
IL38972A (en) 1976-01-30
AU4040472A (en) 1973-09-27
DK137273C (da) 1978-07-17
DE2114420A1 (de) 1972-10-05
BR7201760D0 (pt) 1974-01-08
CH605739A5 (es) 1978-10-13
ATA252572A (de) 1977-11-15
CS163796B2 (es) 1975-11-07
CA980353A (en) 1975-12-23
CS163797B2 (es) 1975-11-07
PL83328B1 (es) 1975-12-31
FR2130659B1 (es) 1975-03-14
FR2130659A1 (es) 1972-11-03
IL38972A0 (en) 1972-05-30
BE781212A (fr) 1972-09-25
DD96946A5 (es) 1973-04-12
CS168694B2 (es) 1976-06-29
US3770748A (en) 1973-11-06
ZA721653B (en) 1972-12-27
AT344169B (de) 1978-07-10
GB1359600A (en) 1974-07-10
SE374918B (es) 1975-03-24
DK137273B (da) 1978-02-13
CS163798B2 (es) 1975-11-07
NL7203986A (es) 1972-09-27
AU465561B2 (en) 1973-09-27

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