ES395080A1 - Un metodo de inhibicion de la hidrolisis de acido acetilsa-licilico. - Google Patents
Un metodo de inhibicion de la hidrolisis de acido acetilsa-licilico.Info
- Publication number
- ES395080A1 ES395080A1 ES395080A ES395080A ES395080A1 ES 395080 A1 ES395080 A1 ES 395080A1 ES 395080 A ES395080 A ES 395080A ES 395080 A ES395080 A ES 395080A ES 395080 A1 ES395080 A1 ES 395080A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrochloride
- hydrolysis
- inhibiting
- propyxyphene
- carboxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 title abstract 2
- 230000007062 hydrolysis Effects 0.000 title abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 title abstract 2
- 230000002401 inhibitory effect Effects 0.000 title abstract 2
- -1 carboxyethyl Chemical group 0.000 abstract 9
- 229960001138 acetylsalicylic acid Drugs 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 125000004066 1-hydroxyethyl group Chemical group [H]OC([H])([*])C([H])([H])[H] 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229960004193 dextropropoxyphene Drugs 0.000 abstract 1
- XLMALTXPSGQGBX-GCJKJVERSA-N dextropropoxyphene Chemical compound C([C@](OC(=O)CC)([C@H](C)CN(C)C)C=1C=CC=CC=1)C1=CC=CC=C1 XLMALTXPSGQGBX-GCJKJVERSA-N 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 125000006301 indolyl methyl group Chemical group 0.000 abstract 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000004372 methylthioethyl group Chemical group [H]C([H])([H])SC([H])([H])C([H])([H])* 0.000 abstract 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/618—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
- A61K31/621—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate having the hydroxy group in position 2 esterified, e.g. benorylate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pyrrole Compounds (AREA)
- Specific Conveyance Elements (AREA)
- Meat, Egg Or Seafood Products (AREA)
- Processing Of Meat And Fish (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7250470A | 1970-09-15 | 1970-09-15 | |
| US17787071A | 1971-09-03 | 1971-09-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES395080A1 true ES395080A1 (es) | 1974-12-01 |
Family
ID=26753427
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES395080A Expired ES395080A1 (es) | 1970-09-15 | 1971-09-14 | Un metodo de inhibicion de la hidrolisis de acido acetilsa-licilico. |
Country Status (18)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5115094B2 (enrdf_load_stackoverflow) * | 1972-11-01 | 1976-05-14 | ||
| US6300362B1 (en) | 1990-07-25 | 2001-10-09 | Novartis Ag (Formerly Sandoz Ltd.) | Stabilized pharmaceutical compositions comprising acid donors |
-
1971
- 1971-09-10 PH PH12832A patent/PH10793A/en unknown
- 1971-09-13 EG EG401/71*UA patent/EG10517A/xx active
- 1971-09-14 DE DE2145947A patent/DE2145947C3/de not_active Expired
- 1971-09-14 ES ES395080A patent/ES395080A1/es not_active Expired
- 1971-09-14 DK DK449471AA patent/DK131368B/da not_active IP Right Cessation
- 1971-09-14 NL NLAANVRAGE7112647,A patent/NL174428C/xx not_active IP Right Cessation
- 1971-09-14 SE SE7111649A patent/SE388124B/xx unknown
- 1971-09-14 NO NO3410/71A patent/NO134931C/no unknown
- 1971-09-14 GB GB4275071A patent/GB1317234A/en not_active Expired
- 1971-09-14 OA OA54363A patent/OA03913A/xx unknown
- 1971-09-14 CA CA122,786A patent/CA997678A/en not_active Expired
- 1971-09-15 FR FR7133206A patent/FR2106539B1/fr not_active Expired
- 1971-09-15 BE BE772610A patent/BE772610A/xx not_active IP Right Cessation
- 1971-09-15 AR AR237956A patent/AR192893A1/es active
- 1971-09-15 RO RO68211A patent/RO61105A/ro unknown
- 1971-09-15 IE IE1169/71A patent/IE35644B1/xx unknown
- 1971-09-15 AT AT801871A patent/AT309668B/de not_active IP Right Cessation
-
1976
- 1976-09-08 HK HK547/76*UA patent/HK54776A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2145947B2 (de) | 1973-02-22 |
| SE388124B (sv) | 1976-09-27 |
| DE2145947A1 (de) | 1972-03-30 |
| FR2106539A1 (enrdf_load_stackoverflow) | 1972-05-05 |
| NO134931B (enrdf_load_stackoverflow) | 1976-10-04 |
| BE772610A (fr) | 1972-03-15 |
| NO134931C (enrdf_load_stackoverflow) | 1977-01-12 |
| IE35644B1 (en) | 1976-04-14 |
| PH10793A (en) | 1977-09-07 |
| DK131368C (enrdf_load_stackoverflow) | 1975-12-01 |
| FR2106539B1 (enrdf_load_stackoverflow) | 1974-11-15 |
| EG10517A (en) | 1976-01-31 |
| IE35644L (en) | 1972-03-15 |
| OA03913A (fr) | 1975-08-14 |
| RO61105A (enrdf_load_stackoverflow) | 1976-08-15 |
| GB1317234A (en) | 1973-05-16 |
| CA997678A (en) | 1976-09-28 |
| DK131368B (da) | 1975-07-07 |
| DE2145947C3 (de) | 1973-09-27 |
| AR192893A1 (es) | 1973-03-21 |
| HK54776A (en) | 1976-09-17 |
| NL174428C (nl) | 1984-06-18 |
| NL7112647A (enrdf_load_stackoverflow) | 1972-03-17 |
| NL174428B (nl) | 1984-01-16 |
| AT309668B (de) | 1973-08-27 |
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