ES394979A1 - A procedure for the preparation of substitute benzopyranes. (Machine-translation by Google Translate, not legally binding)
- Google Patents
A procedure for the preparation of substitute benzopyranes. (Machine-translation by Google Translate, not legally binding)
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Beecham Group PLC
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Beecham Group PLC
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Publication of ES394979A1publicationCriticalpatent/ES394979A1/en
A procedure for the preparation of substituted benzopyrans of general formula (II) **(See formula)** (where R1 | is a non-aromatic hydrocarbon group of 1 to 6 carbon atoms; R2 is a cyclic heteroaromatic group containing 5 or 6 ring atoms; and R3 and R4, which may, be the same or different, represent hydrogen, a non-aromatic hydrocarbon group containing 1 to 20 carbon atoms or a hydroxyl group or derivative thereof) or salts thereof when appropriate, the method of which is to react a chromanone of general formula (III) **(See formula)** with an organometallic compound of general formula R2X, where X is an alkali metal or a magnesium-halogen group, treat with a source of protons to release a compound of general formula (IV) **(See formula)** and allowing or dehydrating this compound to give a compound of general formula (II). (Machine-translation by Google Translate, not legally binding)
ES394979A1970-09-101971-09-10A procedure for the preparation of substitute benzopyranes. (Machine-translation by Google Translate, not legally binding)
ExpiredES394979A1
(en)
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A procedure for the preparation of pharmacodyamically active derivatives of hydroxyalcohylpiperazine. (Machine-translation by Google Translate, not legally binding)